Roy Sarkar, Tapasree individual record
Research Assistant Professor
Positions:
overview

Aberrant activation of the biological process, termed epithelial-mesenchymal transition (EMT) plays an important role

in the acquisition of malignant phenotypes as well as cancer stem (CSC) properties by epithelial cancer cells. EMT facilitates the metastatic dissemination which is the major cause of cancer related mortality. The main focus of my work is to identify the molecular mechanisms that induce EMT and to develop novel therapeutic strategies for preventing and treating metastasis.

education and training
selected publications
Academic Articles17
  • Maity, A. K., Lee, S. C., Hu, L., Bell-pederson, D., Mallick, B. K., & Sarkar, T. R. (2021). Circadian gene selection for time-to-event phenotype by integrating CNV and RNAseq data. Chemometrics and Intelligent Laboratory Systems. 212, 104276-104276.
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  • Maity, A. K., Lee, S. C., Mallick, B. K., & Sarkar, T. R. (2020). Bayesian structural equation modeling in multiple omics data with application to circadian genes.. Bioinformatics. 36(13), 3951-3958.
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  • Carrow, J. K., Singh, K. A., Jaiswal, M. K., Ramirez, A., Lokhande, G., Yeh, A. T., ... Gaharwar, A. K. (2020). Photothermal modulation of human stem cells using light-responsive 2D nanomaterials.. Proc Natl Acad Sci U S A. 117(24), 13329-13338.
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  • Pearson, S. J., Roy Sarkar, T., McQueen, C. M., Elswood, J., Schmitt, E. E., Wall, S. W., ... Porter, W. W. (2019). ATM-dependent activation of SIM2s regulates homologous recombination and epithelial-mesenchymal transition.. Oncogene. 38(14), 2611-2626.
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  • Vijay, G. V., Zhao, N. a., Den Hollander, P., Toneff, M. J., Joseph, R., Pietila, M., ... Mani, S. A. (2019). GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer.. Breast Cancer Res. 21(1), 37.
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Chapters1
  • Sarkar, T. R., McNeal, C. J., Meininger, C. J., Niu, Y., Mallick, B. K., Carroll, R. J., & Wu, G. (2021). Dietary Intakes of Amino Acids and Other Nutrients by Adult Humans. MATHEMATICAL MODELLING IN EXPERIMENTAL NUTRITION. Wu, G.. (Eds.), Amino Acids in Nutrition and Health. Advances in Experimental Medicine and Biology. 211-227. Springer International Publishing.
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Conference Papers4
  • Sarkar, T. R., Sphyris, N., Schmitt, E., Wyatt, G., Wall, S., & Porter, W (2018). The role of effective energy restriction on metastatic tumor growth. The FASEB Journal. 32(S1), 811.2-811.2.
  • Mendoza-Villanueva, D. Y., Kim, S., Ali, H. R., Sharan, S., Sarkar, T. R., Caldas, C., Landberg, G., & Sterneck, E (2013). Abstract 3464: CEBPD (C/EBP) acts as a tumor suppressor in hormone receptor positive breast cancer cells and may serve as biomarker to predict the need for adjuvant therapy.. Clinical Research, Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. 73(8), 3464-3464.
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  • Balamurugan, K., Sarkar, T. R., Wang, J. M., Sharan, S., Anver, M. M., Sterneck, E., & Leighty, R (2011). The tumor suppressor C/EBP delta (CEBPD) promotes metastasis of MMTV-Neu mouse mammary tumors and augments mTOR/AKT/HIF-1 activity through inhibition of FBXW7 expression. CLINICAL & EXPERIMENTAL METASTASIS. 28(2), 185-185.
  • Sarkar, T. R., Strong, C. L., Sibhatu, M. B., Pike, L. M., & McIntosh, C. A (2007). Cloning, Expression and Characterization of a Putative Flavonoid Glucosyltransferase from Grapefruit (Citrus Paradisi) Leaves. CONCEPTS IN PLANT METABOLOMICS. 247-257.
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Repository Documents / Preprints1
Email
tsarkar@bio.tamu.edu
First Name
Tapasree
Last Name
Roy Sarkar
mailing address
Texas A & M University; 525 Lubbock St; Butler Hall, 3258
College Station, TX 77843
USA