Chakraborty, Sanjukta
individual record
Assistant Professor
Positions:
- Assistant Professor, Medical Physiology, College of Medicine
UN Sustainable Development Goals:
UN Sustainable Development Goals:
overview
My research program is primarily focused on the central theme of inflammation as a prime modulator of lymphatic associated pathologies. One primary area of interest in my laboratory is to determine how an inflammatory tumor-lymphatic microenvironment contributes to cancer metastasis and progression. Lymph node metastasis is a prime prognostic indicator of tumor aggressiveness. Studies in my lab focus on the molecular interactions between the tumor cells and the surrounding microenvironment that promote lymph node metastasis. Further we are also interested in delineating the role of the microbiota in cancer progression and metabolic disorders.
education and training
- Ph.D. in Cancer genetics, Indian Institute of Science Bangalore - (Bengaluru, India)
- Texas A&M Health Science Center - (College Station, Texas, United States), Postdoctoral Training
selected publications
Academic Articles44
- OBrien, A., Zhou, T., White, T., Medford, A., Chen, L., Kyritsi, K., ... Glaser, S (2022).
FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in theMdr2 / Mouse Model of Primary Sclerosing Cholangitis. Hepatology Communications.
- Ceci, L., Zhou, T., Lenci, I., Meadows, V., Kennedy, L., Li, P., ... Baiocchi, L (2022). Molecular Mechanisms Linking Risk Factors to Cholangiocarcinoma Development. Cancers. 14(6), 1442-1442.
- Pham, L., Kyritsi, K., Zhou, T., Ceci, L., Baiocchi, L., Kennedy, L., ... Sato, K (2022). The Functional Roles of Immune Cells in Primary Liver Cancer. The American Journal of Pathology.
- Selahi, A., Fernando, T., Chakraborty, S., Muthuchamy, M., Zawieja, D. C., & Jain, A. (2022). Lymphangion-chip: a microphysiological system which supports co-culture and bidirectional signaling of lymphatic endothelial and muscle cells. Lab on a Chip. 22(1), 121-135.
- Meadows, V., Baiocchi, L., Kundu, D., Sato, K., Fuentes, Y., Wu, C., ... Francis, H. (2021). Biliary Epithelial Senescence in Liver Disease: There Will Be SASP. Frontiers in Molecular Biosciences. 8, 803098.
Chapters2
- Zhang, X., Chakraborty, S., Muthuchamy, M., & Zawieja, D. C. (2021). Isolation of Lymphatic Muscle Cells (LMCs) from Rat Mesentery. Methods Mol Biol. Methods in Molecular Biology. 137-141. Springer US.
- Foskett, A. M., Chakraborty, S., & Muthuchamy, M. (2013). Lymphangiogenesis. Immunology of the Lymphatic System. 3-33. Springer New York.
Conference Papers20
- Chen, L., Kennedy, L., Kyritsi, K., Wu, C., Ceci, L., Ekser, B., ... Glaser, S. S. (2021). FREE FATTY ACIDS-INDUCED ACTIVATION OF THE ALPHA-CALCITONIN GENE-RELATED PEPTIDE (ACGRP)/CALCITONIN RECEPTOR-LIKE RECEPTOR (CRLR)/RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 (RAMP1) AXIS REGULATES MIR-125B EXPRESSION VIA TLR4 IN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD). HEPATOLOGY. 74, 1063A-1064A.
- Kyritsi, K., Kennedy, L., Carpino, G., Wu, N., Chen, L., Meyer, A. A., ... Glaser, S. S. (2021). INHIBITION OF THE SUBSTANCE P/NEUROKININ RECEPTOR (SP/NK1R) AXIS AMELIORATES LIVER PHENOTYPES IN A MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD). HEPATOLOGY. 74, 1073A-1073A.
- Wu, N., Zhou, T., Carpino, G., Meyer, A. A., Ceci, L., Zhang, W., ... Glaser, S. S. (2021). KNOCKOUT OF BILIARY NEUROKININ 1 RECEPTOR (NK1R) AMELIORATES LIVER PHENOTYPES IN ALCOHOL ASSOCIATED LIVER DISEASE (ALD). HEPATOLOGY. 74, 226A-226A.
- Wilcox, B. K., Navaneethabalakrishnan, S., Martinez, K. A., Pournouri, A., Henley, M. R., Goodlett, B. L., ... Mitchell, B. M. (2021). Abstract MP52: Hypertensive Stimuli Indirectly Stimulate Mouse Mesometrial Lymphangiogenesis Through Immune Cells. Hypertension. 78(Suppl_1),
- Seelig, C., Kumaravel, S., Roy, S., Singh, S., Glaser, S., & Chakraborty, S. (2021). Serotonin Induces Inflammatory Cytokine Production and Regulates Lymphatic Endothelial Cell Function. The FASEB Journal. 35(S1),
Repository Documents / Preprints2
- Johnson, S. C., Chakraborty, S., Drosou, A., Cunnea, P., Tzovaras, D., Nixon, K., ... Moore, J. E. (2020). Inflammatory state of lymphatic vessels and miRNA profiles associated with relapse in ovarian cancer patients.
- Lee, Y., Chakraborty, S., & Muthuchamy, M (2020). Roles of sarcoplasmic reticulum Ca2+ATPase pump in the impairments of lymphatic contractile activity in a metabolic syndrome rat model.
researcher on
Principal Investigator2
Co-Principal Investigator1
awards and honors
recent teaching activities
- BICH691 Research Instructor
- BIOT684 Direct Prof Internship: In-ab Instructor
- BIOT684 Directed Pro Internship: In-ab Instructor
- BIOT684 Directed Prof Internship Instructor
- BIOT684 Directed Prof Internship Instructor
Email
schakraborty@tamu.edu
First Name
Sanjukta
Last Name
Chakraborty
mailing address
Texas A&M Health Science Center; Medical Physiology; 2416 MREBII
Bryan, TX 77807
USA
UN Sustainable Development Goals:
UN Sustainable Development Goals: