Chakraborty, Sanjukta
individual record
Assistant Professor
Positions:
- Assistant Professor, Medical Physiology, College of Medicine
overview
My research program is primarily focused on the central theme of inflammation as a prime modulator of lymphatic associated pathologies. One primary area of interest in my laboratory is to determine how an inflammatory tumor-lymphatic microenvironment contributes to cancer metastasis and progression. Lymph node metastasis is a prime prognostic indicator of tumor aggressiveness. Studies in my lab focus on the molecular interactions between the tumor cells and the surrounding microenvironment that promote lymph node metastasis. Further we are also interested in delineating the role of the microbiota in cancer progression and metabolic disorders.
education and training
- Ph.D. in Cancer genetics, Indian Institute of Science Bangalore - (Bengaluru, India)
- Texas A&M Health Science Center - (College Station, Texas, United States), Postdoctoral Training
selected publications
Academic Articles36
- Wu, N., Ceci, L., Zhou, T., Francis, H. L., Kennedy, L., Kyritsi, K., ... Alpini, G. (2021). 233 KNOCKDOWN OF THE MT1 MELATONIN RECEPTOR AMELIORATES THE PHENOTYPES OF THE MDR2-/- MOUSE MODEL OF PRIMARY SCLEROSING CHOLANGITIS (PSC) BY DOWNREGULATION OF ORPHAN GPR50 RECEPTOR-PROMOTED CONSTITUTIVE TGF-β1 RECEPTOR SIGNALING.. GASTROENTEROLOGY. 160(6), s-768.
- Roy, S., Kumaravel, S., White, T., O'Brien, A., Seelig, C., Chauhan, R., ... Chakraborty, S. (2021). Fr382 TUMOR-LYMPHATIC INTERACTIONS IN AN INFLAMED MICROENVIRONMENT ACTIVATES CXCR2-CXCL5-YAP SIGNALING AXIS AND ENHANCES LYMPHANGIOGENESIS AND TUMOR MIGRATION IN CHOLANGIOCARCINOMA. GASTROENTEROLOGY. 160(6), s-805.
- Baiocchi, L., Sato, K., Ekser, B., Kennedy, L., Francis, H., Ceci, L., ... Alpini, G. (2020). Cholangiocarcinoma: bridging the translational gap from preclinical to clinical development and implications for future therapy. Expert Opinion on Investigational Drugs. 30(4), 1-11.
- Kumaravel, S., Abbey, C. A., Bayless, K. J., & Chakraborty, S. (2020). The β1-integrin plays a key role in LEC invasion in an optimized 3-D collagen matrix model. American Journal of Physiology - Cell Physiology. 319(6), c1045-c1058.
- Kuchibhotla, A., Chakraborty, S., & Banerjee, D. (2020). Experimental validation of numerical predictions for “Deviant” density enhancement of protein emulsions in oil (Oleo-Nanofluids). SN Applied Sciences. 2(9), 1617.
Chapters1
- Foskett, A. M., Chakraborty, S., & Muthuchamy, M. (2013). Lymphangiogenesis. Immunology of the Lymphatic System. (pp. 3-33). Springer New York.
Conference Papers11
- Roy, S., Kumaravel, S., Mohanty, S., White, T., O'Brien, A., Ekser, B., ... Chakraborty, S. (2020). LYMPHATIC-CHOLANGIOCARCINOMA INTERACTIONS ALTER TUMOR METABOLISM AND CELLULAR SIGNALING PATHWAYS THAT CONTRIBUTE TO TUMOR PROGRESSION AND METASTASIS. Hepatology. 72, 669A-669A.
- O'Brien, A., White, T., Kyritsi, K., Francis, H. L., Zhou, T., Chakraborty, S., ... Glaser, S. S. (2020). MANIPULATION OF THE MIR-16/FGF-1 AXIS REDUCES PROFIBROTIC, PROLIFERATIVE, AND INFLAMMATORY PHENOTYPES IN THE MDR2-/- MOUSE MODEL OF PRIMARY SCLEROSING CHOLANGITIS (PSC). Hepatology. 72, 309A-310A.
- Muthuchamy, T., Lee, Y., Jayaraman, A., Alaniz, R. C., & Chakraborty, S. (2016). Bacterial Metabolite Indole Alters Inflammatory Signaling Cascades In Human Lymphatic Endothelial Cells. FASEB J. 30,
- Chakraborty, S., Zawieja, S. D., Wei, W., Lee, Y., Zawieja, D. C., & Muthuchamy, M. (2014). LPS induced changes in immune cell recruitment and impairment of lymphatic contractility during inflammation. ANGIOGENESIS. 17(4), 944-944.
- Hooks, J., Caulk, A. W., Gleason, R. L., Chakraborty, S., Muthuchamy, M., & Dixon, J. B. (2014). The effects of substrate stiffness of lymphatic muscle cell phenotype in vitro. ANGIOGENESIS. 17(4), 965-965.
researcher on
awards and honors
recent teaching activities
- BICH691 Research Instructor
- BIOT684 Direct Prof Internship: In-ab Instructor
- BIOT684 Directed Pro Internship: In-ab Instructor
- BIOT684 Directed Prof Internship Instructor
- BIOT684 Directed Prof Internship Instructor
Email
schakraborty@tamu.edu
First Name
Sanjukta
Last Name
Chakraborty
mailing address
Texas A&M Health Science Center; Medical Physiology; 2416 MREBII
Bryan, TX 77807
USA