Brandt, Paul
individual record
Associate Professor
Positions:
- Associate Professor, Neuroscience and Experimental Therapeutics, College of Medicine
- Associate Dean for Academic Technology and Curriculum Innovation, College of Medicine, Health Science Center
overview
Understanding how the target cells "interpret" hormonal signals is the primary focus of our laboratory.Most of our research centers on regulation of steroid hormone-transduced signals. One area of study is the calcium-dependent regulation of glucocorticoid and androgen receptor-mediated transcription. A second major area of interest concerns glucocorticoid and steroid sex hormone regulation of nitric oxide (NO) production. Other areas of interest in our laboratory are: development of androgen-independence in prostate cancer; stress responses in PMCA1(-) cell lines; and the involvement of NO in dry eye syndrome.
education and training
- University of California, Irvine - (Irvine, California, United States), Postdoctoral Training 1992
- Ph.D. in Biochemistry, University of Kentucky - (Lexington, Kentucky, United States) 1990
selected publications
Academic Articles21
- Wang, H., DuBois, D. W., Tobery, A. N., Griffith, W. H., Brandt, P., & Frye, G. D (2013). Long-lasting distortion of GABA signaling in MS/DB neurons after binge-like ethanol exposure during initial synaptogenesis.. Brain Res. 1520, 36-50.
- Browning, J. L., Patel, T., Brandt, P. C., Young, K. A., Holcomb, L. A., & Hicks, P. B (2005). Clozapine and the mitogen-activated protein kinase signal transduction pathway: implications for antipsychotic actions.. Biol Psychiatry. 57(6), 617-623.
- Beauregard, C., & Brandt, P (2004). Down regulation of interleukin-1beta-induced nitric oxide production in lacrimal gland acinar cells by sex steroids.. Curr Eye Res. 29(1), 59-66.
- Brandt, P. C., & Vanaman, T. C (2004). Studies of calmodulin-dependent regulation.. Methods Mol Biol. 284, 111-127.
- Beauregard, C., & Brandt, P. C (2003). Peroxisome proliferator-activated receptor agonists inhibit interleukin-1beta-mediated nitric oxide production in cultured lacrimal gland acinar cells.. J Ocul Pharmacol Ther. 19(6), 579-587.
Chapters2
- BRANDT, P. C., & VANAMAN, T. C (2012). Calmodulin and Ion Flux Regulation. Calmodulin and Signal Transduction. 397-471. Elsevier.
- Brandt, P. C (1998). Calmodulin Regulated Ion Transport Systems". Van Eldik, L. J., & Watterson, D. M. (Eds.), Calmodulin and Signal Transduction. 397-471. Academic Press.
Conference Papers1
- Franks, J. J., Wamil, A. W., Janicki, P. K., Horn, J. L., Franks, W. T., Janson, V. E., Vanaman, T. C., & Brandt, P. C (1998). Anesthetic-induced alteration of Ca2+ homeostasis in neural cells: a temperature-sensitive process that is enhanced by blockade of plasma membrane Ca2+-ATPase isoforms.. Anesthesiology. 89(1), 149-164.
recent teaching activities
- MEID707 Endo/repro Sci, Hum Sexuality Instructor
- MEID708 Integument/musculoskeletal Instructor
Email
paul-c-brandt@tamu.edu
First Name
Paul
Last Name
Brandt
mailing address
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1114 TAMUS
Bryan, TX 77807
USA