overview

My laboratory is interested in the regulatory interfaces between novel lipid-mediated signal transduction pathways and important cellular functions. The focus of our work is the phosphatidylinositol/ phosphatidylcholine transfer proteins (PITPs), a ubiquitous but enigmatic class of proteins. Ongoing projects in the laboratory derive from a multidisciplinary approach that encompasses biochemical characterization of novel members of the metazoan PITP family, and the application of genetic, molecular and biophysical approaches to detailed structural and functional analyses of PITPs.

selected publications
Academic Articles150
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  • Wang, Y., Yuan, P., Grabon, A., Tripathi, A., Lee, D., Rodriguez, M., ... Bankaitis, V. A. (2020). Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase.. J Cell Biol. 219(5), e201907128.
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  • Bankaitis, V. A., & Wang, Y. (2020). Lipoprotein Lipase Sorting: Sphingomyelin and a Proteoglycan Show the Way.. Trends Cell Biol. 30(3), 170-172.
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  • McDermott, M. I., Wang, Y., Wakelam, M., & Bankaitis, V. A. (2020). Mammalian phospholipase D: Function, and therapeutics.. Prog Lipid Res. 78, 101018-101018.
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Books1
Chapters3
  • Davison, J. M., Bankaitis, V. A., & Ghosh, R. (2012). Devising powerful genetics, biochemical and structural tools in the functional analysis of phosphatidylinositol transfer proteins (PITPs) across diverse species.. METHODS IN CELL BIOLOGY, VOL 49. Methods in Cell Biology. 249-302. Elsevier.
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  • McGee, T. P., Fung, M., & Bankaitis, V. A. (1993). Chapter 7 Genetic studies on the functions of membrane-forming phospholipids. New Comprehensive Biochemistry. Protein-Lipid Interactions. 163-190. Elsevier.
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  • Bankaitis, V. A., Ryan, J. P., Rasmussen, B. A., & Bassford, P. J. (1985). Chapter 3 The Use of Genetic Techniques to Analyze Protein Export in Escherichia coli. Current Topics in Membranes and Transport. Current Topics in Membranes and Transport. 105-150. Elsevier.
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Conference Papers3
  • Koe, C. T., Tan, Y. S., Lonnfors, M., Hur, S. K., Yu, F., Bankaitis, V. A., & Wang, H. (2017). Vibrator regulates asymmetric division of Drosophila neuroblasts. Mechanisms of Development. 145, S62-S62.
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  • Lnnfors, M., Grabon, A., McGrath, K. R., Tripathi, A., Lete, M. G., Somerharju, P., & Bankaitis, V. A. (2017). The Use of Fluorescently Labeled Lipids to Determine Dynamics of Protein Mediated In Vitro Lipid Transfer. Biophysical Journal. 112(3), 326a-326a.
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  • Quinones, M. C., Bankaitis, V. A., & Smirnova, T. I. (2014). Structure, Dynamics, and Electrostatic Effects on Membrane Binding of Nod Peptides. Biophysical Journal. 106(2), 295a-295a.
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Internet Publications1
  • Bankaitis, V. A., & Xie, Z. (2016). New autism research: a nutrient called carnitine might counteract gene mutations linked with ASD risks. - An article submitted to The Conversation
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chaired theses and dissertations
Email
vytas_1023@tamu.edu
First Name
Vytas
Last Name
Bankaitis
mailing address
Texas A&M Health Science Center; Molecular And Cellular Medicine; 1114 TAMUS
College Station, TX 77845
USA