overview

The overall goal of my laboratory is to understand mechanisms regulating inflammation and thereby develop strategies for modulating immune responses. One project focuses on the role of the cytokine thymic stromal lymphopoietin (TSLP) as the master switch in the pathobiology of allergic inflammation and asthma. The role of allergens and respiratory viruses on the induction of TSLP transcription by mast cells and epithelial cells is being studied in vitro and in human subjects.

selected publications
Academic Articles88
  • McElvaine, A. T., Hawkins-Salsbury, J. A., Arora, V. M., Gladwin, M. T., Goldenring, J. R., Huston, D. P., ... Gbadegesin, R. A (2021). Innovations in MD-only physician-scientist training: experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative.. J Clin Invest. 131(10), e149948.
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  • Huston, D. P (2019). Unneutral neutrophils in patients with late-phase allergic reactions.. J Allergy Clin Immunol. 144(1), 46-48.
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  • Huston, D. P., & Sabato, V (2018). Decoding the Enigma of Urticaria and Angioedema.. J Allergy Clin Immunol Pract. 6(4), 1171-1175.
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  • Huston, D. P., & Cox, L. S (2014). Evidence-based evaluation for allergies to avoid inappropriate testing, diagnosis, and treatment.. JAMA Intern Med. 174(8), 1223-1224.
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  • Cromheecke, J. L., Nguyen, K. T., & Huston, D. P (2014). Emerging role of human basophil biology in health and disease.. Curr Allergy Asthma Rep. 14(1), 408.
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Books3
  • Eissa, N. T., & Huston, D. P. (2015). Therapeutic targets in airway inflammation. CRC Press.
  • Beer, M. H., Robert S Porter, M. D., & Jones, T. V (2006). The Merck Manual of Diagnosis and Therapy. Merck.
  • Eissa, N. T., & Huston, D. P (2003). Preface.
Chapters5
  • Olmstead, S. M., Venzor, J., & Huston, D. P (1998). Systemic Lupus Erythematosus. Suki and Massry’s THERAPY OF RENAL DISEASES AND RELATED DISORDERS. 459-478. Springer US.
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  • Takatsu, K., Dickason, R. R., & Huston, D. P (1997). Interleukin-5. Growth Factors and Cytokines in Health and Disease. Cytokines. 143-200. Elsevier.
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  • HUSTON, D. P (1994). DIAGNOSTIC LABORATORY IMMUNOLOGY - PREFACE. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA. R13-R13.
  • SHEARER, W. T., PAUL, M. E., SMITH, C. W., & HUSTON, D. P (1994). LABORATORY ASSESSMENT OF IMMUNE-DEFICIENCY DISORDERS. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA. 265-299.
  • Huston, D. P., & Bressler, R. B (1992). Urticaria and angioedema.. Medical Clinics of North America. 805-840. Elsevier bv.
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Conference Papers42
  • Goldblatt, D. L., Fouts, A., Valverde-Ha, G., Martinez-Moczygemba, M., Huston, D., Tuvim, M. J., Dickey, B. F., & Evans, S. E. (2021). Aerosolized Toll-Like Receptor Agonists Modulate Type 2 Allergic Inflammation. TP6. TP006 CLINICAL STUDIES OF ALLERGIC AIRWAY DISEASES, LUPUS, AND EOSINOPHILIC DISEASES, American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. 204(1), a1347-a1347.
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  • Goldblatt, D. L., Valverde Ha, G., Fouts, A., Wali, S., Martinez-Moczygemba, M., Huston, D. P., ... Evans, S. E. (2020). Aerosolized Toll-Like Receptor Agonists Suppress Allergic Inflammation. B101. NEW BIOLOGICAL TREATMENTS FOR ASTHMA, American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. 201, a4271-a4271.
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  • Goldblatt, D. L., Valverde, G., Tkachman, S., Martinez-Mocygemba, M., Huston, D. P., Tuvim, M. J., Dickey, B. F., & Evans, S. E (2019). Aerosolized Toll-Like Receptor Agonists Suppress House Dust Mite Allergic Asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 199,
  • FARNAM, K., GALICIA, D., SINGH, S., & HUSTON, D (2008). Clinical Immunophenotypic Heterogeneity of Subclinical T cell Leukemia. Journal of Allergy and Clinical Immunology. 121(2), S15-S15.
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  • Berrios-Rivera, J. P., Johnson, M. L., Huston, D. P., & Suarez-Almazor, M. E (2006). Disparities in the use of biologic therapies for the treatment of rheumatoid arthritis.. ARTHRITIS AND RHEUMATISM. 54(9), S48-S49.
chaired theses and dissertations
Email
dhuston@tamu.edu
First Name
David
Last Name
Huston
mailing address
Texas A&M Health Science Center; Ctr For Clinical/Translational Med; 1201 TAMUS
Houston, TX 77030-3303
USA