Shetty, Ashok individual record

Our laboratory is interested in developing clinically applicable strategies that are efficacious for enhancing brain function after injury, disease or aging. The central areas of investigation include the following: (1) Elucidating mechanisms by which transplanted immature neuronal precursors and neural stem cells (NSCs) and/or GABA-ergic precursor cells derived from embryonic, postnatal and adult brain tissues or human induced pluripotent stem cells (hiPSCs) promote brain repair and ease spontaneous recurrent seizures and cognitive dysfunction in prototypes of status epilepticus, chronic temporal lobe epilepsy (TLE) and traumatic brain injury. (2) Studying mechanisms of brain dysfunction in prototypes of Gulf War Illness and developing treatment strategies to ease cognitive and mood impairments in Gulf War Illness. (3) Developing clinically feasible strategies for improving hippocampus neurogenesis, and memory and mood function in aging and neurological diseases via stimulation of endogenous neural stem/progenitor cells. (4) Analyzing promising neuroprotective compounds and drugs for their usefulness to block chronic epilepsy development after an initial precipitating injury such as status epilepticus or traumatic brain injury (TBI) including mild TBI induced by blast shock waves.

education and training
selected publications
Academic Articles151
Conference Papers24
in the news
recent teaching activities
First Name
Last Name
mailing address
Texas A&M Health Science Center; Regenerative Medicine; 1114 TAMUS
Temple, TX 76502-6954