Scholars

Scott Exter Professor

Positions:

Scott Exter Professor, Medical Physiology, Texas A&M University Naresh K. Vashisht College of Medicine

overview

Our research interests are directed towards understanding the complex mechanisms which regulate the expression of specific gene sequences in development. We have focused our studies upon the factors that influence the smooth muscle component of the developing gastrointestinal (G.I.) tract. It has been shown that smooth muscle cells are predominantly derived from mesodermal precursor cells, however the factors regulating the selection of the smooth muscle myogenic pathway is not well defined.

education and training

Vanderbilt University - (Nashville, Tennessee, United States), Postdoctoral Training
Ph.D. in Cell Biology, Baylor College of Medicine - (Houston, Texas, United States) 1985
B.S. in Biology, University of Houston - (Houston, Texas, United States) 1977

selected publications

Academic Articles63

Hammerle, C. M., Sandovici, I., Brierley, G. V., Smith, N. M., Zimmer, W. E., Zvetkova, I., ... Constncia, M. (2020). Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function.. PLoS Genetics. 16(10), e1009069-e1009069.
Abbasgholizadeh, R., Zhang, H., Craft, J. W., Bryan, R. M., Bark, S. J., Briggs, J. M., ... Schwartz, R. J. (2019). Discovery of vascular Rho kinase (ROCK) inhibitory peptides.. Experimental Biology and Medicine. 244(11), 940-951.
Doersch, K. M., Moses, K. A., & Zimmer, W. E. (2016). Synergistic immunologic targets for the treatment of prostate cancer.. Experimental Biology and Medicine. 241(17), 1900-1910.

SDG 3
Goodman, S. R., Petrofes Chapa, R., & Zimmer, W. E. (2015). Spectrin's chimeric E2/E3 enzymatic activity.. Experimental Biology and Medicine. 240(8), 1039-1049.
Fillmore, R. A., Kojima, C., Johnson, C., Kolcun, G., Dangott, L. J., & Zimmer, W. E. (2014). New concepts concerning prostate cancer screening.. Experimental Biology and Medicine. 239(7), 793-804.

Chapters3

Goodman, S. R., & Zimmer, W. E. (2008). Cytoskeleton. Medical Cell Biology. 59-100. Elsevier.
Zimmer, W. E. (2008). Regulation of Gene Expression. Medical Cell Biology. 149-190. Elsevier.
Balczon, R., Bao, L., Zimmer, W. E., Brown, K., Zinkowski, R. P., & Brinkley, B. R. (1994). Analysis of Centrosome Replication Events in Mammalian Cells. The Cell Cycle. 229-235. Springer Nature.

Conference Papers5

Zimmer, W. E. (2006). Spectrin's key role in synaptic transmission. The FASEB Journal. 20(5), A868-A868.
Zimmer, W. E., Stanfel, M. N., Moses, K. A., Chi, X., Takamoto, N., Dean, D. A., & Schwartz, R. J. (2005). The bagpipe homolog Nkx3.2 is an important factor in the specification of bone and intestinal tract mesoderm. Mechanisms of Development. 122, S64-S64.
Van Eldik, L. J., Zimmer, W. E., Barger, S. W., & Watterson, D. M. (1990). Perturbation of the calmodulin system in transformed cells.. Advances in Experimental Medicine and Biology. 269, 111-120.
Lukas, T. J., Haiech, J., Lau, W., Craig, T. A., Zimmer, W. E., Shattuck, R. L., Shoemaker, M. O., & Watterson, D. M. (1988). Calmodulin and calmodulin-regulated protein kinases as transducers of intracellular calcium signals.. Cold Spring Harbor Symposia on Quantitative Biology. 53 Pt 1(0), 185-193.
ZIMMER, W. E., CHANG, K. S., BERGSMA, D., & SCHWARTZ, R. (1983). ORGANIZATION AND EXPRESSION OF THE CHICKEN ACTIN MULTIGENE FAMILY DURING MYOGENESIS. Journal of Cell Biology. 97(5), A330-A330.