Wu, Xin individual record
Research Assistant Professor
- Research Assistant Professor, Neuroscience and Experimental Therapeutics, School of Medicine
Mechanical forces are known to stimulate a number of cell signaling pathways, including those initiated by or resulting in ion channel activation. My recent research in cardiovascular and neuronal systems focuses on: (1) Which ion channels are activated by mechanical stress; (2) Which ion channels are modulated by integrins; (3) How integrin-mediated signaling pathways modulate ion channel function and mechanotransduction in physiological and pathological conditions; (4) Epilepsy study, Neurosteroids and New Drug Development.
education and training
- Texas A&M Health Science Center - (College Station, Texas, United States), Postdoctoral Training
- M.S. in Cardiovascular Physiology, Soochow University - (Suzhou, China) 1993
- M.D. in Medicine, Nantong University - (Nantong, China) 1985
- Wu, S. X., & Wu, X. (2022). Stay-at-home and face mask policy intentions inconsistent with incidence and fatality during the US COVID-19 pandemic.. Front Public Health. 10, 990400.
- Reddy, D. S., Golub, V. M., Ramakrishnan, S., Abeygunaratne, H., Dowell, S., & Wu, X. (2022). A Comprehensive and Advanced Mouse Model of Post-Traumatic Epilepsy with Robust Spontaneous Recurrent Seizures.. Curr Protoc. 2(6), e447.
- Reddy, D. S., Zaayman, M., Kuruba, R., & Wu, X. (2021). Comparative profile of refractory status epilepticus models following exposure of cholinergic agents pilocarpine, DFP, and soman.. Neuropharmacology. 191, 108571-108571.
- Wu, X., Shetty, A. K., & Reddy, D. S. (2021). Long-term changes in neuroimaging markers, cognitive function and psychiatric symptoms in an experimental model of Gulf War Illness.. Life Sci. 285, 119971-119971.
- Reddy, S. D., Wu, X., Kuruba, R., Sridhar, V., & Reddy, D. S. (2020). Magnetic resonance imaging analysis of long-term neuropathology after exposure to the nerve agent soman: correlation with histopathology and neurological dysfunction.. Ann N Y Acad Sci. 1480(1), 116-135.
- Wu, X., Sun, Z., Meininger, G. A., & Muthuchamy, M. (2012). Application of Atomic Force Microscopy Measurements on Cardiovascular Cells. Peng, X., & Antonyak, M. (Eds.), Cardiovascular Development Methods and Protocols. 229-244. Humana Press.
- Gui, P., Chao, J., Wu, X., Yang, Y., Davis, G. E., & Davis, M. J. (2010). Coordinated regulation of vascular Ca2+ and K+ channels by integrin signaling.. Becchetti, A., & Arcangeli, A. (Eds.), Integrins and Ion Channels. 69-79. Springer Nature.
- Muthuchamy, M., Chakraborty, S., Wu, X., Sarin, V., & Heaps, C. L. (2012). Exercise-Induced Changes in Mechanotransduction Improve Myocardial Function in a Porcine Model of Chronic Occlusion. CIRCULATION. 126(21),
- Wu, X., Sun, Z., Ross, R. S., Meininger, G. A., & Muthuchamy, M. (2010). Fibronectin-Induced Mechanotransduction Mediated by alpha (5) beta (1) Integrin Requires Calcium and Vinculin in Mouse Cardiomyocytes. CIRCULATION. 122(21),
- Tong, C. W., Wu, X., Sadayappan, S., Hudmon, A., Muthuchamy, M., Ralphe, J. C., Valdivia, H. H., & Moss, R. L. (2010). Frequency Dependent Phosphorylation of Cardiac Myosin Binding Protein-C Mediates Acceleration of Myocardial Relaxation to Support Normal Diastolic Function. CIRCULATION. 122(21),
- Tong, C. W., Wu, X., Scherman, J. A., Ralphe, J. C., Muthuchamy, M., Valdivia, H. H., & Moss, R. L. (2009). Cardiac Myosin Binding Protein C Regulates Cross-bridge Kinetics to Affect Diastolic Function. CIRCULATION. 120(18), S871-S871.
- Wu, X., Meininger, G. A., & Muthuchamy, M. (2009). Fibronectin Increases Mouse Cardiac Contractility via Alpha (5) Beta (1) Integrin. CIRCULATION. 120(18), S872-S872.
Repository Documents / Preprints2
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS
Bryan, TX 77807-3260