Wu, Chaodong
individual record
Professor and Presidential Impact Fellow
Positions:
- Professor, Nutrition, College of Agriculture and Life Sciences
- Professor, Texas A&M AgriLife Research, Texas A&M University
overview
The long-term goal of Dr. Wu's research program is to elucidate the mechanisms underlying the pathogenesis of obesity and overnutrition-associated metabolic diseases including insulin resistance, diabetes, and fatty liver disease so that novel dietary and/or pharmacological approaches can be developed for preventing and/or treating metabolic diseases. Using molecular, cellular, and integrative approaches, the Wu lab is focused on investigating the interaction between metabolism and inflammation.
education and training
- Ph.D. in Medical Science, Peking University - (Beijing, Beijing, China) 1998
- M.A.Sc. in Medical Science, Tongji Hospital - (Wuhan, China) 1992
selected publications
Academic Articles119
- Zhang, W., Guo, X., Chen, L., Chen, T., Yu, J., Wu, C., & Zheng, J. (2021). Ketogenic Diets and Cardio-Metabolic Diseases. Frontiers in Endocrinology. 12, 753039.
- Lin, S., Li, Y., Wang, D., Huang, C., Marino, D., Bollt, O., ... Yang, S. (2021). Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression. Cancer Letters. 518, 230-242.
- Matthews, D. R., Li, H., Zhou, J., Li, Q., Glaser, S., Francis, H., Alpini, G., & Wu, C. (2021). Methionine- and Choline-Deficient Diet–Induced Nonalcoholic Steatohepatitis Is Associated with Increased Intestinal Inflammation. The American Journal of Pathology. 191(10), 1743-1753.
- Lin, X., Zhang, Y., He, X., Chen, Y., Chen, N., Liu, J., ... Xiao, X. (2021). The Choline Metabolite TMAO Inhibits NETosis and Promotes Placental Development in GDM of Humans and Mice. Diabetes. 70(10), 2250-2263.
- Xu, H., Zhu, B., Li, H., Jiang, B., Wang, Y., Yin, Q., ... Wu, C. (2021). Adipocyte inducible 6-phosphofructo-2-kinase suppresses adipose tissue inflammation and promotes macrophage anti-inflammatory activation. The Journal of Nutritional Biochemistry. 95, 108764-108764.
Chapters1
- Woo, S., Guo, T., & Wu, C. (2016). Hepatic Lipogenesis: Nutritional Control and Pathophysiological Relevance. Hepatic De Novo Lipogenesis and Regulation of Metabolism. 211-234. Springer International Publishing.
Conference Papers32
- Chen, L., Kennedy, L., Kyritsi, K., Wu, C., Ceci, L., Ekser, B., ... Glaser, S. S. (2021). FREE FATTY ACIDS-INDUCED ACTIVATION OF THE ALPHA-CALCITONIN GENE-RELATED PEPTIDE (ACGRP)/CALCITONIN RECEPTOR-LIKE RECEPTOR (CRLR)/RECEPTOR ACTIVITY-MODIFYING PROTEIN 1 (RAMP1) AXIS REGULATES MIR-125B EXPRESSION VIA TLR4 IN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD). HEPATOLOGY. 74, 1063A-1064A.
- Kyritsi, K., Kennedy, L., Carpino, G., Wu, N., Chen, L., Meyer, A. A., ... Glaser, S. S. (2021). INHIBITION OF THE SUBSTANCE P/NEUROKININ RECEPTOR (SP/NK1R) AXIS AMELIORATES LIVER PHENOTYPES IN A MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD). HEPATOLOGY. 74, 1073A-1073A.
- Wu, N., Zhou, T., Carpino, G., Meyer, A. A., Ceci, L., Zhang, W., ... Glaser, S. S. (2021). KNOCKOUT OF BILIARY NEUROKININ 1 RECEPTOR (NK1R) AMELIORATES LIVER PHENOTYPES IN ALCOHOL ASSOCIATED LIVER DISEASE (ALD). HEPATOLOGY. 74, 226A-226A.
- Zhou, T., Wu, N., Carpino, G., Kennedy, L., Meyer, A. A., Ceci, L., ... Alpini, G. (2021). KNOCKOUT OF SECRETIN RECEPTOR (SR) AMELIORATES LIVER PHENOTYPES IN A MOUSE MODEL OF ALCOHOL ASSOCIATED LIVER DISEASE (ALD). HEPATOLOGY. 74, 226A-227A.
- Ceci, L., Carpino, G., Kennedy, L., Wu, N., Chen, L., Kyritsi, K., ... Alpini, G. (2021). MELATONIN BINDS MT1 TO IMPROVE THE PHENOTYPES OF PRIMARY SCLEROSING CHOLANGITIS (PSC) THROUGH CLOCK GENES/MIR-200B/MASPIN/GST SIGNALING. HEPATOLOGY. 74, 273A-274A.
in the news
researcher on
Principal Investigator5
- Protective role of adenosine 2A receptor in NAFLD awarded by National Institutes of Health 2013 - 2019
- Metabolic regulation of adipocyte-macrophage crosstalk in obesity awarded by National Institutes of Health 2013 - 2018
Co-Principal Investigator1
awards and honors
recent teaching activities
- NFSC475 Nutr & Physiolog Chem Instructor
- NFSC485 Directed Studies Instructor
- NFSC491 Research Instructor
- NFSC642 Nutritional Bich Ii Instructor
- NFSC681 Seminar Instructor
chaired theses and dissertations
- Woo, Shih Lung (2016-12). Beneficial Effects of Metformin in Diet-Induced Obesity Associated Non-Alcoholic Fatty Liver Disease. (Doctoral Dissertation)
- Botchlett, Rachel Erin (2015-12). Nutrient Regulation of PFKFB3/iPFK2 and Its Role in Regulating Diet-Induced Inflammation in Intestinal Epithelial Cells. (Doctoral Dissertation)
- Qi, Ting (2015-08). Involvement of PFKFB3/iPFK2 in Beneficial Effects of Metformin on 3T3-L1 Adipocytes and Temporal Effects of Pioglitazone on Adipocytes. (Master's Thesis)
- Guo, Ting (2015-05). Beneficial Effects of Berberine on Nonalcoholic Fatty Liver Disease (NAFLD). (Master's Thesis)
- Guo, Xin (2013-05). A Role for PFKFB3/IPFK2 in Overnutrition-Associated Adipose Tissue and Intestine Inflammatory Responses and Insulin Resistance. (Doctoral Dissertation)
Email
cdwu@tamu.edu
First Name
Chaodong
Last Name
Wu
mailing address
Texas A&M University; Nutrition; 2253 TAMU
College Station, TX 77843-2253
USA