Research in my lab focuses on male-female differences in normal cardiovascular function, and in the development of various diseases, including hypertension, coronary artery disease, and stroke, and the roles of the sex hormones in these male-female differences in cardiovascular disease. A major topic of study in my lab is the so-called \"estrogen paradox\" which reveals protective effects of this female sex hormone in younger women and animals, but deleterious effects in older females.
- University of Tennessee Health Science Center - (Memphis, Tennessee, United States), Postdoctoral Training 1988
- Ph.D. in Medical Physiology, University of Arizona - (Tucson, Arizona, United States) 1984
- M.S. in Comparative Physiology, San Diego State University - (San Diego, California, United States) 1974
- B.S. in Vertebrate Zoology, San Diego State University - (San Diego, California, United States) 1972
- Perusquia, M., Hanson, A. E., Meza, C. M., Kubli, C., Herrera, N., & Stallone, J. N. (2018). Antihypertensive responses of vasoactive androgens in an in vivo experimental model of preeclampsia. J Steroid Biochem Mol Biol. 178, 65-72.
- Yu, X., Stallone, J. N., Heaps, C. L., & Han, G. (2018). The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries. PLoS ONE. 13(1), e0191418-e0191418.
- Yu, X., Zhang, Q., Zhao, Y., Schwarz, B. J., Stallone, J. N., Heaps, C. L., & Han, G. (2017). Activation of G protein-coupled estrogen receptor 1 induces coronary artery relaxation via Epac/Rap1-mediated inhibition of RhoA/Rho kinase pathway in parallel with PKA. PLoS ONE. 12(3), e0173085-e0173085.
- Perusquia, M., Herrera, N., Ferrer, M., & Stallone, J. N. (2017). Antihypertensive effects of androgens in conscious, spontaneously hypertensive rats. J Steroid Biochem Mol Biol. 167, 106-114.
- Deer, R. R., & Stallone, J. N. (2016). Effects of estrogen on cerebrovascular function: age-dependent shifts from beneficial to detrimental in small cerebral arteries of the rat. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 310(10), H1285-H1294.
- Stallone, J. N., & White, R. E. (2005). Nongenomic androgen-induced vasorelaxation is structurally-specific and involves vascular smooth muscle K+ channel activation via nitric oxide-cyclic-gmp pathway. STEROIDS. 70(5-7), 481-482.
- Li, M., Kuo, L., & Stallone, J. N. (2002). Estrogen enhances contractile responses of rat aorta by upregulating expression of cyclooxygenase-2 and thromboxame synthase. CIRCULATION. 106(19), 211-211.
- Fulton, C. T., Freeman, E. J., & Stallone, J. N. (1999). Long-term tamoxifen (TMX)-treatment enhances endothelium-dependent nitric oxide (NO) and constrictor prostanoid (PG) function in female rat aorta. CIRCULATION. 100(18), 220-220.
- Osborn, Pamela (2014-05). The Relative Contributions of COX-1 and COX-2 to Vascular Biosynthesis of Prostacyclin and Thromboxane. (Master's Thesis)
- Deer, Rachel Renee (2013-08). Physiological Factors that Modulate Vascular Function: States of Endothelial Dysfunction and Therapeutic Interventions. (Doctoral Dissertation)
- Sellers, Minga Miown (2008-12). The role of estrogen receptors in the contribution of constrictor prostanoids to aortic coarctation-induced hypertension. (Doctoral Dissertation)
- Li, Min (2005-05). Constrictor prostanoid-potentiated vascular contraction: regulation of endothelial and vascular smooth muscle mechanism by estrogen. (Doctoral Dissertation)
- Baltzer, Wendy Irene (2003-12). The role of constrictor prostanoids in the development of aortic coarctation-induced hypertension in male and female rats. (Doctoral Dissertation)