Trache, Andreea individual record
Associate Professor

The research in my laboratory focuses on the study of cellular responses to mechano-chemical stresses from a biophysical perspective. Biophysics research represents an applied field of science at the interface of physics, biology, engineering, and medicine. Our lab uses live vascular cells as a model system because endothelial and smooth muscle cells reside 'in vivo' in a mechanically active environment that is continuously changing. Using real-time imaging of live cells is the only way to directly monitor cellular responses to mechano-chemical stimulation. Moreover, single-cell imaging experiments allow discrete measurements of transient microscopic events that may be masked by a macroscopic average behavior, and will aid in understanding such behavior.

selected publications
Academic Articles28
  • Trache, A., Massett, M. P., & Woodman, C. R. (2020). Vascular smooth muscle stiffness and its role in aging. STORE-OPERATED CALCIUM CHANNELS. Membrane Biomechanics. (pp. 217-253). Elsevier.
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  • Trache, A., Xie, L., Huang, H., Glinsky, V. V., & Meininger, G. A. (2018). Applications of Atomic Force Microscopy for Adhesion Force Measurements in Mechanotransduction. Methods in Molecular Biology. Nanoscale Imaging. (pp. 515-528). Springer New York.
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  • Sun, Z., Trache, A., Meissner, K., & Meininger, G. A. (2012). Integration of AFM with Optical Microscopy Techniques. Atomic Force Microscopy in Liquid. (pp. 211-229). Wiley-VCH Verlag GmbH & Co. KGaA.
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  • Trache, A., & Meininger, G. A. (2008). Total Internal Reflection Fluorescence (TIRF) Microscopy. Current Protocols in Microbiology. (pp. 2a.2.1-2a.2.22). Wiley.
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  • Trache, A., & Meininger, G. A. (2008). Atomic Force Microscopy (AFM). Current Protocols in Microbiology. (pp. 2c.2.1-2c.2.17). Wiley.
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Conference Papers32
recent teaching activities
chaired theses and dissertations
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mailing address
Texas A&M Health Science Center; Medical Physiology; 1114 TAMUS
College Station, TX 77843-1114