Hook, Michelle
individual record
Associate Professor
Positions:
- Associate Professor, Neuroscience and Experimental Therapeutics, School of Medicine
overview
The primary focus of my current research is examining the effects of morphine on recovery of function after spinal cord injury. This research includes examination of the potential for addiction after SCI as well as the behavioral and molecular changes associated with administration of morphine in a rodent model of spinal cord injury.
education and training
- Ph.D. in Physiology, University of New England - (Armidale, New South Wales, Australia) 1998
selected publications
Academic Articles64
- Rau, J., Weise, L., Moore, R., Terminel, M., Brakel, K., Cunningham, R., ... Hook, M. A. (2023). Intrathecal minocycline does not block the adverse effects of repeated, intravenous morphine administration on recovery of function after SCI.. Exp Neurol. 359, 114255-114255.
- Rau, J., Hemphill, A., Araguz, K., Cunningham, R., Stefanov, A., Weise, L., & Hook, M. A. (2022). Adverse Effects of Repeated, Intravenous Morphine on Recovery after Spinal Cord Injury in Young, Male Rats Are Blocked by a Kappa Opioid Receptor Antagonist.. J Neurotrauma. 39(23-24), 1741-1755.
- Terminel, M. N., Bassil, C., Rau, J., Trevino, A., Ruiz, C., Alaniz, R., & Hook, M. A. (2022). Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury.. BMC Neurosci. 23(1), 58.
- Stampas, A., Hook, M., Korupolu, R., Jethani, L., Kaner, M. T., Pemberton, E., Li, S., & Francisco, G. E. (2022). Evidence of treating spasticity before it develops: a systematic review of spasticity outcomes in acute spinal cord injury interventional trials.. Ther Adv Neurol Disord. 15, 17562864211070657-175628642110706.
- Metzger, C. E., Rau, J., Stefanov, A., Joseph, R. M., Allaway, H., Allen, M. R., & Hook, M. A. (2022). Inflammaging and Bone Loss in a Rat Model of Spinal Cord Injury.. J Neurotrauma.
Chapters3
- Hau, J., Schapiro, S., & Hook, M. (2013). Animal Models of Spinal Cord Injury. Handbook of Laboratory Animal Science, Volume III, Third Edition. 1-42. Taylor & Francis.
- Hook, M. A. (2013). Handbook of Laboratory Animal Science, Volume III. Hau, J., & Schapiro, S. J. (Eds.), Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models. 1-42. CRC Press.
- Hook, M. A. (2004). The Evolution of Lateralized Motor Functions. Comparative Vertebrate Cognition. 325-370. Springer Nature.
Conference Papers16
- Rau, J., Hemphill, A., Araguz, K., Cunningham, R., & Hook, M. (2021). BLOCKING KOR ACTIVATION PREVENTS MORPHINE-INDUCED ATTENUATION OF RECOVERY FOLLOWING SCI. JOURNAL OF NEUROTRAUMA. 38(14), A6-A6.
- Rau, J., Hemphill, A., Araguz, K., Cunningham, R., & Hook, M. (2021). BLOCKING KOR ACTIVATION PREVENTS MORPHINE-INDUCED ATTENUATION OF RECOVERY FOLLOWING SCI. JOURNAL OF NEUROTRAUMA. 38(14), A52-A53.
- Stefanov, A., Dundumulla, R., Hemphill, A., Joseph, R. M., Brakel, K., Rau, J., Montgomery, K. S., & Hook, M. A. (2021). DEPRESSIVE-LIKE BEHAVIOR IN SPINALLY INJURED MALE RATS IS ASSOCIATED WITH A DECLINE IN SPATIAL LEARNING. JOURNAL OF NEUROTRAUMA. 38(14), A79-A79.
- Terminel, M. N., Brakel, K., & Hook, M. (2018). OPIOID-IMMUNE INTERACTIONS AFTER SCI. JOURNAL OF NEUROTRAUMA. 35(16), A19-A19.
- Brakel, K., Aceves, A., Aceves, M., & Hook, M. (2017). ELEVATED BASELINE LEVELS OF INTERLEUKIN-6 ARE ASSOCIATED DEPRESSION AFTER SPINAL CORD INJURY. JOURNAL OF NEUROTRAUMA. 34(13), A116-A116.
Repository Documents / Preprints2
- Wang, W., Xie, X., Zhuang, X., Huang, Y., Tan, T., Gangal, H., ... Wang, J. (2022). Striatal -Opioid Receptor Activation Triggers Direct-Pathway GABAergic Plasticity to Induce Negative Affect.
- Terminel, M. N., Bassil, C., Rau, J., Trevino, A., Ruiz, C., Alaniz, R., & Hook, M. A. (2022). Morphine-induced changes in the function of microglia and macrophages after spinal cord injury.
researcher on
Principal Investigator6
Co-Principal Investigator1
Collaborator1
recent teaching activities
- BICH491 Hnr-research Instructor
- BICH491 Research Instructor
- MSCI691 Research Credit: Medical Sci Instructor
- NRSC485 Directed Studies Instructor
- NRSC485 Hnr-directed Studies Instructor
chaired theses and dissertations
- Maldonado, Sioui (2014-12). Psychological Well-Being and Spinal Cord Injury Recovery: A Two-Way Street?. (Doctoral Dissertation)
- Woller, Sarah Ann (2013-08). Characterization of Morphine Self-Administration Following Spinal Cord Injury. (Doctoral Dissertation)
- Woller, Sarah Ann (2010-05). Analgesia or Addiction: Implications for Morphine Use After Spinal Cord Injury. (Master's Thesis)
Email
michellehook@tamu.edu
First Name
Michelle
Last Name
Hook
mailing address
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS
Bryan, TX 77804
USA