Dr. Walzem's core research focus within the laboratory is directed towards understanding how the structure of triglyceride-rich lipoproteins influences their ability to carry out specific nutrient delivery tasks. Her studies include identification of mechanisms and regulatory processes that control the assembly of trigylceride-rich lipoproteins in issues, structural studies of lipoproteins themselves and physiological studies to determine substrate properties and metabolic fates of different types of lipoproteins. Diet can significantly alter lipoprotein physiology through multiple mechanisms, and studies of diet effects provides a significant sub-theme to the research program. A variety of species are used to address specific questions, however, avian and human lipoprotein metabolism as it relates to egg production and atherogenesis, respectively, are emphasized.
Academic Articles122
- Wu, X., Roussell, M. A., Hill, A. M., Kris-Etherton, P. M., & Walzem, R. L. (2021). Baseline Insulin Resistance Is a Determinant of the Small, Dense Low-Density Lipoprotein Response to Diets Differing in Saturated Fat, Protein, and Carbohydrate Contents. Nutrients. 13(12), 4328-4328.
- THOMSEN, M. N., SKYTTE, M. J., SAMKANI, A., ASTRUP, A., FRYSTYK, J., CHABANOVA, E., ... KRARUP, T. (2021). 38-LB: Reduced Carbohydrate and Increased Protein and Fat during Weight Loss Improve the Atherogenic Lipid Profile in Type 2 Diabetes. Diabetes. 70(Supplement_1),
- Chou, P., Lin, P., Wu, S., Wang, C., Chung, T., Walzem, R. L., Lai, L., & Chen, S. (2021). Differential Modulation of 25-hydroxycholecalciferol on Innate Immunity of Broiler Breeder Hens.. Animals (Basel). 11(6), 1742-1742.
- Beathard, K., Georghiades, N., Walzem, R., Talcott, S., Smith, S., & Riechman, S. (2021). The Impact of Egg Consumption on Visual Cognitive Performance in the Nutrition, Vision, and Cognition in Health: Egg (IONHealth-Egg) Study. Current Developments in Nutrition. 5(Supplement_2), 3-3.
- Price, T. R., Baskaran, S. A., Moncada, K. L., Minamoto, Y., Klemashevich, C., Jayuraman, A., ... Walzem, R. L. (2021). Whole and Isolated Protein Fractions Differentially Affect Gastrointestinal Integrity Markers in C57Bl/6 Mice Fed Diets with a Moderate-Fat Content.. Nutrients. 13(4), 1251-1251.
Chapters4
- O’Connor, A. J., Halpern, G. M., & Walzem, R. L. (2016). Nonalcoholic Components of Wine and Atherosclerotic Cardiovascular Disease. Beverage Impacts on Health and Nutrition. 83-99. Springer International Publishing.
- Kieffer, A. J., & Walzem, R. L. (2015). 14. Modulation of lipids, lipoproteins, and other biomarkers with egg consumption and exercise. Handbook of eggs in human function. 231-252. Wageningen Academic Publishers.
- Pacheco, L., Walzem, R., Noratto, G., & Mertens-Talcott, S. (2008). Health Benefits of Phytochemicals for Older Adults. Handbook of Nutrition in the Aged, Fourth Edition. 229-247. CRC Press.
- Walzem, R. L., & German, J. B. (2004). The French Paradox. Beverages in Nutrition and Health. 31-48. Humana Press.
Conference Papers46
- Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Chabanova, E., ... Haugaard, S. B. (2021). Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes. DIABETOLOGIA. 64(SUPPL 1), 60-60.
- Price, T. R., Moncada, K. L., Blake, A., Suchodolski, J., & Walzem, R. L. (2019). Dietary Matrix Alters Fecal Lipids and Lipoprotein Profiles in Healthy C57Bl/6 Mice. The FASEB Journal. 33(S1), 795.14-795.14.
- Haugaard, S. B., Anholm, C., Kumarathurai, P., Pedersen, L. R., Samkani, A., Walzem, R. L., ... Sajadieh, A. (2018). Liraglutide and metformin may rock and roll the most atherogenic LDL fraction in patients with diabetes and ischaemic heart disease on stable statin therapy: a randomised trial. DIABETOLOGIA. 61, S351-S352.
- Price, T. R., & Walzem, R. L. (2018). Degree of Dietary Refinement Alters Apparent Gut Permeability. The FASEB Journal. 32(S1), 762.1-762.1.
- Pedersen, L. R., Olsen, R. H., Walzem, R. L., Haugaard, S. B., & Prescott, E. (2017). A one-year intervention combining weight loss and exercise increases the proportion of lipoprotein constituted by HDL and HDL particle size. EUROPEAN HEART JOURNAL. 38, 310-311.
- De-extinction efforts are being directed at reviving lost bird species Genetic Literacy October 28, 2020
Principal Investigator3
Investigator1
- Nutrition, Biostatistics and Bioinformatics Training Grant awarded by DHHS-NIH-National Cancer Institute 2013 - 2021
- NFSC485 Directed Studies Instructor
- NFSC650 Nutr & Met Minerals Instructor
- NFSC691 Research Instructor
- NFSC691 Research: In-ab Instructor
- NUTR485 Directed Studies Instructor