Wooley, Karen
individual record
Distinguished Professor
Positions:
- Distinguished Professor, Chemistry, College of Arts and Sciences
UN Sustainable Development Goals:
UN Sustainable Development Goals:
overview
Our research activities combine organic syntheses, polymerization strategies and polymer modification reactions in creative ways to afford unique macromolecular structures, which have been designed as functional nanostructures, polymer systems having unique macromolecular architectures, and/or degradable polymers. The emphasis is upon the incorporation of functions and functionalities into selective regions of polymer frameworks. In some cases, the function is added at the small molecule, monomer, stage, prior to polymerization, whereas, in other cases, chemical modifications are performed upon polymers or at the nanostructure level; each requires a strategic balance of chemical reactivity and the ultimate composition and structure.
education and training
- Ph.D. in Chemistry, Cornell University - (Ithaca, New York, United States) 1993
- B.S. in Chemistry, Oregon State University - (Corvallis, Oregon, United States) 1988
selected publications
Academic Articles405
- Pang, C., Wang, H., Zhang, F., Patel, A. K., Lee, H. P., & Wooley, K. L. (2023). Glucose-derived superabsorbent hydrogel materials based on mechanically-interlocked slide-ring and triblock copolymer topologies. JOURNAL OF POLYMER SCIENCE.
- Sayed, F., Eissa, N. G., Shen, Y., Hunstad, D. A., Wooley, K. L., & Elsabahy, M. (2022). Morphologic design of nanostructures for enhanced antimicrobial activity.. J Nanobiotechnology. 20(1), 536.
- Yang, J., Wang, X., Wang, B., Park, K., Wooley, K., & Zhang, S. (2022). Challenging the fundamental conjectures in nanoparticle drug delivery for chemotherapy treatment of solid cancers.. Adv Drug Deliv Rev. 190, 114525-114525.
- Singh, M., Dong, M., Wu, W., Nejat, R., Tran, D. K., Pradhan, N., ... Karim, A. (2022). Enhanced Dielectric Strength and Capacitive Energy Density of Cyclic Polystyrene Films.. ACS Polym Au. 2(5), 324-332.
- Su, L. u., Dalby, K. S., Luehmann, H., Elkassih, S. A., Cho, S., He, X., ... Wooley, K. L. (2022). Ultrasmall, elementary and highly translational nanoparticle X-ray contrast media from amphiphilic iodinated statistical copolymers. Acta Pharmaceutica Sinica B.
Books1
Chapters11
- Mohamed, N., Elsabahy, M., Wooley, K. L., & Eissa, N. G. (2022). Chapter 3 Nanomaterials and immune system* * Adapted from Elsabahy, M., & Wooley, K. L. (2013). Cytokines as biomarkers of nanoparticle immunotoxicity. Chemical Society Reviews, 42(12), 55525576. https://doi.org/10.1039/C3CS60064E.. Immunomodulatory Effects of Nanomaterials. 65-114. Elsevier.
- Elsabahy, M., & Wooley, K. L. (2022). Chapter 4 Methods for evaluation of the immunomodulatory effects of nanoparticles* * Adapted with permission from Elsabahy, M., Wooley, K. L., Hendricksen, A. & Oh, K. (2019). Multiplexing techniques for measurement of the immunomodulatory effects of particulate materials: Precautions when testing micro- and nano-particles. Methods, 158, 81-85. https://doi.org/10.1016/j.ymeth.2019.01.006.. Immunomodulatory Effects of Nanomaterials. 115-127. Elsevier.
- Elsabahy, M., & Wooley, K. L. (2022). Chapter 6 Precautions during evaluation of immunotoxicity of particulate materials*. Immunomodulatory Effects of Nanomaterials. 139-143. Elsevier.
- Elsabahy, M., & Wooley, K. L. (2022). Chapter 7 Data analysis and interpretation* * Adapted with permission from Elsabahy, M., Wooley, K. L., Hendricksen, A., & Oh, K. (2021). Multiple analyte profiling (MAP) index as a powerful diagnostic and therapeutic monitoring tool. Methods, 190, 2632. https://doi.org/10.1016/j.ymeth.2020.03.006.. Immunomodulatory Effects of Nanomaterials. 145-168. Elsevier.
- Elsabahy, M., & Wooley, K. L. (2014). Core-Shell Nanoparticles for Biomedical Applications. Handbook of Nanobiomedical Research. 475-517. World Scientific Publishing.
Conference Papers94
- Zhang, S., Langer, R., & Wooley, K. L. (2015). Simple, novel and applicable strategies for innovative medical solutions. Education Division 2015 - Core Programming Area at the 2015 AIChE Annual Meeting. 318.
- Heo, G. S., Cho, S., & Wooley, K. L. (2014). Aldehyde-functional polycarbonates as reactive platforms. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 248,
- Wooley, K. L. (2014). Award Address (ACS Award in Polymer Chemistry sponsored by ExxonMobil Chemical Company). Targeted applications as inspirations to develop strategies toward functionally-sophisticated nanoscopic macromolecules with diverse compositions, structures, and properties. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 247,
- Zhang, F., Smolen, J. A., Zhang, S., Raymond, J. E., Li, R., Shah, P. N., ... Wooley, K. L. (2014). Design and synthesis of degradable polyphosphoester-based nanoparticles carrying silver-based antimicrobials as therapeutics for lung infections. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 247,
- Seetho, K., Lynd, N. A., Raymond, J. E., Hawker, C. J., & Wooley, K. L. (2014). Determining the extent of interaction of zwitterionic vs. blended ionic polymers for use in supramolecular self-assembly via thermal and mechanical characterization. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 248,
in the news
- Texas A&M Announces Members And Charge Of Commission On Diversity, Equity, and Inclusion Texas A&M Today July 13, 2020
- Texas A&M Chemist Karen Wooley Elected To National Academy of Sciences Texas A&M Today April 29, 2020
patents
Patents10
- Wooley, K. L., Felder, S. E., Versaw, B. A., Jahnke, A. A., Link, L. A., Wooley, M. W., Hinton, C. A., & Howell, W. (2019). Degradable polycarbonate sport fishing materials.
- Neumann, W. L., Dorshow, R. B., Freskos, J. N., Wooley, K. L., Lee, N. S., Lin, Y., & Sun, G. (2017). Functional, cross-linked nanostructures for tandem optical imaging and therapy.
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- Cho, S., Sun, G., Wooley, K., Thackeray, J., & Trefonas III, P. (2016). Self-assembled structures, method of manufacture thereof and articles comprising the same.
- Cho, S., Sun, G., Wooley, K. L., Thackeray, J. W., & Trefonas, I. (2016). Self-assembled structures, method of manufacture thereof and articles comprising the same.
researcher on
Principal Investigator14
Investigator1
- REU Site: Sustainable Chemistry at Texas A&M University awarded by National Science Foundation 2019 - 2022
awards and honors
- Presidential Impact Fellows conferred by Texas A&M University - (College Station, Texas, United States) - Lifetime Entitlement, Inaugural Class 2017
- Association of Former Students University-Level Distinguished Achievement Award, The conferred by Texas A&M University - (College Station, Texas, United States) - University-Level Research 2016
recent teaching activities
- BIOT684 Directed Pro Internship: In-ab Instructor
- BIOT684 Directed Prof Internshp: In-ab Instructor
- CHEM228 Organic Chemistry Ii Instructor
- CHEM466 Polymer Chemistry Instructor
- CHEM470 Industrial Chemistry Instructor
chaired theses and dissertations
- Zigmond, Jennifer Summerhill (2016-12). Development and Testing of Intricate, Amphiphilic Crosslinked Hyperbranched Fluoropolymers with Integrated Liquid Crystalline Properties as Anti-Icing Coatings in Aerospace and Defense Applications. (Doctoral Dissertation)
- Link, Lauren A (2015-12). Degradable Polycarbonate Networks Derived from Quinic Acid and Designed for Biomedical Applications. (Doctoral Dissertation)
- Zhang, Fuwu (2015-08). Design and Development of Polymeric Nanoparticles for the Delivery of Therapeutics. (Doctoral Dissertation)
- Lim, Young (2015-08). Development of Polyphosphoester-Based Polymeric Nanoparticles as Delivery Carriers for Silver-Based Antimicrobial Agents for Treatment of Infectious Diseases. (Doctoral Dissertation)
- Cho, Sangho (2015-08). Advanced Photoresist Technologies by Intricate Molecular Brush Architectures. (Doctoral Dissertation)
Email
wooley@tamu.edu
First Name
Karen
Last Name
Wooley
mailing address
Texas A&M University; Chemistry Department; 3255 TAMU
College Station, TX 77842-3012
USA
UN Sustainable Development Goals:
UN Sustainable Development Goals: