Wooley, Karen individual record
Distinguished Professor

Our research activities combine organic syntheses, polymerization strategies and polymer modification reactions in creative ways to afford unique macromolecular structures, which have been designed as functional nanostructures, polymer systems having unique macromolecular architectures, and/or degradable polymers. The emphasis is upon the incorporation of functions and functionalities into selective regions of polymer frameworks. In some cases, the function is added at the small molecule, monomer, stage, prior to polymerization, whereas, in other cases, chemical modifications are performed upon polymers or at the nanostructure level; each requires a strategic balance of chemical reactivity and the ultimate composition and structure.

selected publications
Academic Articles369
  • Tran, D. K., Rashad, A. Z., Darensbourg, D. J., & Wooley, K. L. (2021). Sustainable synthesis of CO2-derived polycarbonates from d-xylose. Polymer Chemistry. 12(37), 5271-5278.
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  • Song, Y., Elsabahy, M., Collins, C. A., Khan, S., Li, R., Hreha, T. N., ... Wooley, K. L. (2021). Morphologic Design of Silver-Bearing Sugar-Based Polymer Nanoparticles for Uroepithelial Cell Binding and Antimicrobial Delivery.. Nano Lett. 21(12), 4990-4998.
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  • Elsabahy, M., Song, Y., Eissa, N. G., Khan, S., Hamad, M. A., & Wooley, K. L. (2021). Morphologic design of sugar-based polymer nanoparticles for delivery of antidiabetic peptides.. J Control Release. 334, 1-10.
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  • Elsabahy, M., Wooley, K. L., Hendricksen, A., & Oh, K. (2021). Multiple analyte profiling (MAP) index as a powerful diagnostic and therapeutic monitoring tool.. Methods. 190, 26-32.
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  • Nguyen, T. P., Easley, A. D., Kang, N., Khan, S., Lim, S., Rezenom, Y. H., ... Wooley, K. L. (2021). Polypeptide organic radical batteries.. Nature. 593(7857), 61-66.
  • Mller, A., & Wooley, K. L. (2012). Introduction. Elsevier.
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  • Caut, S. I., Lee, N. S., Lin, L. Y., & Wooley, K. L. (2012). Individual Nano-Objects Obtained via Hierarchical Assembly of Polymer Building Blocks. Polymer Science: A Comprehensive Reference. 775-820. Elsevier.
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  • Chen, Z., Cheng, C., Germack, D. S., Gopalan, P., van Horn, B. A., Venkataraman, S., & Wooley, K. L. (2007). Complex Functional Macromolecules. Macromolecular Engineering. 1341-1385. Wiley.
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Conference Papers90
  • Zhang, S., Langer, R., & Wooley, K. L. (2015). Simple, novel and applicable strategies for innovative medical solutions. Education Division 2015 - Core Programming Area at the 2015 AIChE Annual Meeting. 318.
  • Heo, G. S., Cho, S., & Wooley, K. L. (2014). Aldehyde-functional polycarbonates as reactive platforms. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 248,
  • Seetho, K., Lynd, N. A., Raymond, J. E., Hawker, C. J., & Wooley, K. L. (2014). Determining the extent of interaction of zwitterionic vs. blended ionic polymers for use in supramolecular self-assembly via thermal and mechanical characterization. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 248,
  • Borguet, Y. P., Noel, A. C., Lim, Y. H., Gunsten, S. P., Brody, S. L., Parameswar, A. R., Taylor, J., & Wooley, K. L. (2014). Development of phosphonium-based shell-crosslinked knedel-like nanoparticles for gene delivery. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 248,
  • Noel, A., Borguet, Y. P., Raymond, J. E., & Wooley, K. L. (2014). Poly(ferulic acid-co-tyrosine), a poly(carbonate-amide) derived from bio-based resources: Synthesis and characterization. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 248,
chaired theses and dissertations
First Name
Last Name
mailing address
Texas A&M University; Chemistry Department; 3255 TAMU
College Station, TX 77842-3012