Winzer-Serhan, Ursula
individual record
Associate Professor
Positions:
- Associate Professor, Neuroscience and Experimental Therapeutics, School of Medicine
overview
I am interested in studying how gene environmental interactions shape the brain during development. In particular, I am interested in how early life exposure to psychoactive drugs, like nicotine and alcohol, permanently shape the brain which could result in long-term cognitive impairments, anxiety, and anti-social behavior. My lab is currently focused on the effects of nicotine. Nicotine interacts with nicotinic acetylcholine receptors (nAChR) which are ligand-gated, pentameric cation channels.
education and training
- Virginia Commonwealth University Medical Center - (Richmond, Virginia, United States), Postdoctoral Training
- University of California, Irvine - (Irvine, California, United States), Postdoctoral Training
- Ph.D. in Cell Biology, University of Bremen - (Bremen, Germany) 1989
- M.S. in Biology, University of Bremen - (Bremen, Germany) 1986
- M.S. in Plant Physiology, University of Florida - (Gainesville, Florida, United States) 1986
selected publications
Academic Articles50
- McCamy, K. M., Rees, K. A., & Winzer-Serhan, U. H. (2022). Peripheral immune challenges elicit differential up-regulation of hippocampal cytokine and chemokine mRNA expression in a mouse model of the 15q13.3 microdeletion syndrome.. Cytokine. 159, 156005-156005.
- Rees, K. A., Halawa, A. A., Consuegra-Garcia, D., Golub, V. M., Clossen, B. L., Tan, A. M., ... Winzer-Serhan, U. H. (2020). Molecular, physiological and behavioral characterization of the heterozygous Df[h15q13]/+ mouse model associated with the human 15q13.3 microdeletion syndrome.. Brain Res. 1746, 147024-147024.
- Halawa, A. A., Rees, K. A., McCamy, K. M., & Winzer-Serhan, U. H. (2020). Central and peripheral immune responses to low-dose lipopolysaccharide in a mouse model of the 15q13.3 microdeletion.. Cytokine. 126, 154879-154879.
- Broide, R. S., Winzer-Serhan, U. H., Chen, Y., & Leslie, F. M. (2019). Distribution of 7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse.. Front Neuroanat. 13, 76.
- Halawa, A. A., Damborsky, J. C., Slaton, G. S., & Winzer-Serhan, U. H. (2018). Activation of immediate early genes by nicotine after chronic neonatal nicotine exposure in brain areas involved in stress and anxiety responses.. Brain Res. 1687, 32-40.
Chapters4
- Winzer-Serhan, U. H. (2023). Chapter 13 Nicotinic acetylcholine receptors in the autonomic nervous system. Primer on the Autonomic Nervous System. 77-80. Elsevier.
- Son, J., & Winzer-Serhan, U. H. (2015). Combined Radioactive and Nonradioactive Double In Situ Hybridization (DISH). In Situ Hybridization Methods. 109-126. Springer Nature.
- Winzer-Serhan, U. H., & Leslie, F. M. (2000). Quantitative Light Microscopic Autoradiography of 2-Adrenergic Radioligand Binding Sites. Adrenergic Receptor Protocols. 507-517. Springer Nature.
- Winzer-Serhan, U. H., & Leslie, F. M. (2000). Quantitative light microscopic autoradiography of alpha 2-adrenergic radioligand binding sites.. Adrenergic Receptor Protocols. 507-517. Humana Press.
Conference Papers3
- Balaraman, S., Tsai, P., Pappalardo, D., Winzer-Serhan, U., & Miranda, R. C. (2012). ETHANOL-RESPONSIVE FETAL NEURAL STEM CELL MIRNAS ARE COMMON TARGETS FOR FETAL TERATOGENS. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 36, 333A-333A.
- DuBois, D. W., Fincher, A. S., Winzer-Serhan, U. H., & Frye, G. D. (2012). VARENICLINE ENHANCES GABAERGIC SYNAPTIC TRANSMISSION AND AMELIORATES ETHANOL-INDUCED DEFICITS IN GABAERGIC SIGNALING IN BASAL FOREBRAIN NEURONS. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 36, 393A-393A.
- DuBois, D. W., Fincher, A. S., Winzer-Serhan, U. H., & Frye, G. D. (2012). VARENICLINE MODULATES GABAERGIC SYNAPTIC TRANSMISSION AND MITIGATES ETHANOL-INDUCED DEFICITS IN GABAERGIC SIGNALING IN BASAL FOREBRAIN NEURONS. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 36, 38A-38A.
in the news
researcher on
Investigator1
recent teaching activities
- BICH491 Hnr-research Instructor
- BICH491 Research Instructor
- GENE491 Hnr-research Instructor
- GENE491 Research Instructor
- GENE491 Research: In-ab Instructor
chaired theses and dissertations
- Huang, Pei-San (2012-05). Effects of Chronic Nicotine Exposure and Lack of High Affinity Nicotinic Receptors on Cortico-Hippocampal Areas in the Aging Mouse Brain. (Doctoral Dissertation)
Email
winzer-serhan@tamu.edu
First Name
Ursula
Last Name
Winzer-Serhan
mailing address
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS
Bryan, TX 77807-3260
USA