My recent research interests have focused on understanding the cellular and molecular mechanisms governing the interaction between a wide array of Neuropsychopharmacological agents and their respective receptors. My past research has focused on understanding 1.) the neuroteratogenic effects of ethanol on the GABAergic inhibitory neurotransmitter system, 2.) the chronic effects of ethanol on excitatory and inhibitory neurotransmitter systems in brain areas regulating anxiety-like behaviors, and 3) the effects of anesthetic agents on learning and memory mechanisms in the hippocampal region of the brain. My lab is also interested in understanding the impact of various pharmacological and environmental agents such as ethanol, benzodiazepines, pesticides, and chemical pollutants on central nervous system development.
- University of Wisconsin - Madison - (Madison, Wisconsin, United States), Postdoctoral Training 2010
- Wake Forest University - (Winston-Salem, North Carolina, United States), Postdoctoral Training 2006
- Ph.D. in Biomedical Sciences and Pharmacology, Texas A&M Health Science Center - (College Station, Texas, United States) 2004
- B.A. in Biology, The University of Texas at Austin - (Austin, Texas, United States) 1998
Academic Articles11
- Montgomery, K. S., Bancroft, E. A., Fincher, A. S., Migut, E. A., Provasek, V., Murchison, D., & DuBois, D. W. (2018). Effects of ethanol and varenicline on female Sprague-Dawley rats in a third trimester model of fetal alcohol syndrome.. ALCOHOL. 71, 75-87.
- Shannonhouse, J. L., DuBois, D. W., Fincher, A. S., Vela, A. M., Henry, M. M., Wellman, P. J., Frye, G. D., & Morgan, C. (2016). Fluoxetine disrupts motivation and GABAergic signaling in adolescent female hamsters.. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 69, 19-30.
- Tsai, P., Bake, S., Balaraman, S., Rawlings, J., Holgate, R. R., Dubois, D., & Miranda, R. C. (2014). MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells.. Biology Open. 3(8), 741-758.
- Griffith, W. H., Dubois, D. W., Fincher, A., Peebles, K. A., Bizon, J. L., & Murchison, D. (2014). Characterization of age-related changes in synaptic transmission onto F344 rat basal forebrain cholinergic neurons using a reduced synaptic preparation.. Journal of Neurophysiology. 111(2), 273-286.
- Wang, H., DuBois, D. W., Tobery, A. N., Griffith, W. H., Brandt, P., & Frye, G. D. (2013). Long-lasting distortion of GABA signaling in MS/DB neurons after binge-like ethanol exposure during initial synaptogenesis.. BRAIN RESEARCH. 1520, 36-50.
Conference Papers1
- Hsiao, S. H., Acevedo, J. L., DuBois, D. W., Smith, K. R., West, J. R., & Frye, G. D. (2001). Early postnatal ethanol intubation blunts GABA(A) receptor up-regulation and modifies 3alpha-hydroxy-5alpha-pregnan-20-one sensitivity in rat MS/DB neurons.. Brain research. Developmental brain research. 130(1), 25-40.
Principal Investigator1
Co-Principal Investigator1
Investigator1
- Estrogens, Ovarian Aging and Calcium Channel Modulation awarded by DHHS-NIH-National Institute On Aging 2012 - 2017
- MEID608 Neuroscience Instructor
- NEXT605 Moleclr Mech. Of Drug Toxin I Instructor
