Zhou, Yubin
individual record
Associate Professor
Positions:
- Associate Professor, Institute of Biosciences and Technology, Health Science Center
overview
The Zhou Lab at Texas A&M is exploring the fascinating frontiers of calcium signaling, optogenteics, epigenetics, immunoengieerning and molecular therapy research with a focus on elucidating the role of calcium channels and DNA modifications in health and diseases and designing better treatment and prevention strategies for cardivaslcuar disorders, autoimmune diseases and cancer. We are particularly interested in understanding how calcium ions are transported across membrane, how ion channels and human epigenome in cells of the immune system can be engineered to achieve tailored function, and how dysregulated ion homeostasis and DNA modifictaions lead to human diseases.
education and training
- Ph.D. in Chemistry, Georgia State University - (Atlanta, Georgia, United States) 2008
- M.S. in Chemistry, Georgia State University - (Atlanta, Georgia, United States) 2007
- M.D. in Internal Medicine, Zhejiang University - (Hangzhou, Zhejiang, China) 2003
selected publications
Academic Articles82
- Guo, L., Li, J., Zeng, H., Guzman, A. G., Li, T., Lee, M., ... Huang, Y. (2020). A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells.. Nature Communications. 11(1), 740.
- Jing, J. i., Liu, G., Huang, Y., & Zhou, Y. (2020). A molecular toolbox for interrogation of membrane contact sites.. Journal of Physiology. 598(9), 1725-1739.
- Yang, X., Ma, G., Zheng, S., Qin, X., Li, X., Du, L., ... Li, M. (2020). Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles.. Journal of the American Chemical Society.
- Ma, G., He, L., Liu, S., Xie, J., Huang, Z., Jing, J. i., ... Zhou, Y. (2020). Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling.. Nature Communications. 11(1), 1039.
- Haruehanroengra, P., Zheng, Y. Y., Zhou, Y., Huang, Y., & Sheng, J. (2020). RNA modifications and cancer. RNA biology. 1-16.
Chapters6
- Ma, G., He, L., Jing, J. i., Tan, P., Huang, Y., & Zhou, Y. (2018). Engineered Cross-Linking to Study the Pore Architecture of the CRAC Channel.. Methods in molecular biology (Clifton, N.J.). Methods in Molecular Biology. (pp. 147-166). Springer New York.
- Zhang, S., He, L., Zhou, Y., & Wang, Y. (2018). Fluorescence-Based Ratiometric Measurement of CRAC Channel Activity in STIM-Orai-Overexpressing HEK-293 Cells.. Methods in molecular biology (Clifton, N.J.). Methods in Molecular Biology. (pp. 17-39). Springer New York.
- Zhang, Y., Zheng, S., Zhou, Y., Gill, D. L., & Wang, Y. (2018). Patch-Clamp Recording of the CRAC Channel Current in STIM-Orai Overexpressing Cells.. Methods in molecular biology (Clifton, N.J.). Methods in Molecular Biology. (pp. 1-16). Springer New York.
- He, L., Zhang, Q., Zhou, Y., & Huang, Y. (2017). Optogenetic approaches to control calcium entry in non-excitable cells. Calcium Entry Channels in Non-Excitable Cells. (pp. 145-160). CRC Press.
- Ma, G., Wen, S., Huang, Y., & Zhou, Y. (2017). The STIM-Orai Pathway: Light-Operated Ca2+ Entry Through Engineered CRAC Channels. MATHEMATICAL MODELLING IN EXPERIMENTAL NUTRITION. STORE-OPERATED CA2+ ENTRY (SOCE) PATHWAYS: EMERGING SIGNALING CONCEPTS IN HUMAN (PATHO)PHYSIOLOGY, 2ND EDITION. (pp. 117-138). Springer International Publishing.
teaching activities
- IBST605 Biomed Rsrch Prfsnl Dvlpmnt Instructor
- IBST691 Research Credit: Medical Sci Instructor
Email
yubinzhou@tamu.edu
First Name
Yubin
Last Name
Zhou
mailing address
Texas A&M University -IBT; Ibt Center For Translational Cancer Research; 1201 TAMUS
Houston, TX 77030-3303
USA