overview

Research in the laboratory is focused on investigating mechanisms by which a variety of biological response modifiers ranging from mechanical signals, hormones and growth factors to environmental chemicals alter cellular signaling pathways and cellular homeostasis.

selected publications
Academic Articles299
  • Elmetwally, M. A., Li, X., Johnson, G. A., Burghardt, R. C., Herring, C. M., Kramer, A. C., ... Wu, G. (2022). Dietary supplementation with l-arginine between days 14 and 25 of gestation enhances NO and polyamine syntheses and the expression of angiogenic proteins in porcine placentae. Amino Acids. 54(2), 193-204.
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  • Li, X., Johnson, G. A., Zhou, H., Burghardt, R. C., Bazer, F. W., & Wu, G. (2022). Microarray analysis reveals an important role for dietary L-arginine in regulating global gene expression in porcine placentae during early gestation. Frontiers in Bioscience-Landmark. 27(1), 1-1.
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  • Shrestha, R., Mohankumar, K., Martin, G., Hailemariam, A., Lee, S., Jin, U., Burghardt, R., & Safe, S. (2021). Flavonoids kaempferol and quercetin are nuclear receptor 4A1 (NR4A1, Nur77) ligands and inhibit rhabdomyosarcoma cell and tumor growth. Journal of Experimental & Clinical Cancer Research. 40(1), 392.
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  • Zhu, C., Li, X., Bazer, F. W., Johnson, G. A., Burghardt, R. C., Jiang, Z., & Wu, G. (2021). Dietary L-arginine supplementation during days 14-25 of gestation enhances aquaporin expression in the placentae and endometria of gestating gilts.. Amino Acids. 53(8), 1287-1295.
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  • McLendon, B. A., Kramer, A. C., Seo, H., Bazer, F. W., Burghardt, R. C., & Johnson, G. A. (2021). Integrin Adhesion Complex Organization in Sheep Myometrium Reflects Changing Mechanical Forces during Pregnancy and Postpartum.. Biology (Basel). 10(6), 508-508.
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Chapters7
  • Zhu, C., Jiang, Z., Johnson, G. A., Burghardt, R. C., Bazer, F. W., & Wu, G. (2022). Nutritional and Physiological Regulation of Water Transport in the Conceptus. MATHEMATICAL MODELLING IN EXPERIMENTAL NUTRITION. Wu, G.. (Eds.), Advances in Experimental Medicine and Biology. 109-125. Springer International Publishing.
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  • Geisert, R. D., Johnson, G. A., & Burghardt, R. C. (2015). Implantation and Establishment of Pregnancy in the Pig.. Advances in anatomy, embryology, and cell biology. Regulation of Implantation and Establishment of Pregnancy in Mammals. 137-163. Springer International Publishing.
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  • Wu, G., Bazer, F. W., Burghardt, R. C., Johnson, G. A., Kim, S. W., Knabe, D. A., ... Spencer, T. E. (2010). Functional amino acids in swine nutrition and production. Dynamics in Animal Nutrition. 69-98.
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  • Burghardt, R. C., & Droleskey, R. (2005). Transmission Electron Microscopy. Current Protocols in Microbiology. John Wiley & Sons, Inc..
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  • Burghardt, R. C., Bowen, J. A., & Bazer, F. W. (1998). Endocrine Control of Trophoblast-Uterine Epithelial Cell Interactions. Bazer, F. W. (Eds.), Endocrinology of Pregnancy. 199-228. Humana Press.
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Conference Papers130
  • Johnson, G. A., Bazer, F. W., Burghardt, R. C., Wu, G., Seo, H., Kramer, A. C., & McLendon, B. A. (2018). Cellular events during ovine implantation and impact for gestation. Animal Reproduction. 15(Suppl. 1), 843-855.
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  • Seo, H., Bazer, F., Burghardt, R., & Johnson, G. (2016). A revised hypothesis for placental syncytialization in sheep. Placenta. 45, 117-117.
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  • Johnson, G., Seo, H., Bazer, F., Burghardt, R., & Bayless, K. (2016). Mechanotransduction drives morphogenesis to develop folding at the uterine-placental interface of Pigs. Placenta. 45, 79-79.
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  • Satterfield, M., Brown, J., Miller, A., Zamora, M., Dunlap, K., Burghardt, R., ... Zhang, R. (2016). Maternal exposure to sulfur based particulate matter alters postnatal growth and health in rats. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 252,
  • Johnson, G. A., Burghardt, J. R., II, T., Reeder, A. T., Nguyen, B. T., & Burghardt, R. C. (2015). Evidence for integrin activation (focal adhesion formation) at the conceptus-maternal interface of pregnant sheep.. BIOLOGY OF REPRODUCTION. 87-87.
Repository Documents / Preprints2
  • Shrestha, R., Mohankumar, K., Martin, G., Hailemariam, A., Lee, S., Jin, U., Burghardt, R., & Safe, S. (2021). Flavonoids Kaempferol and Quercetin are Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands and inhibit Rhabdomyosarcoma Cell and Tumor Growth.
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  • Martinez, J. G., Huang, J. Z., Burghardt, R. C., Barhoumi, R., & Carroll, R. J. (2010). Use of multiple singular value decompositions to analyze complex intracellular calcium ion signals.
patents
Patents1
researcher on
chaired theses and dissertations
Email
rburghardt@cvm.tamu.edu
First Name
Robert
Last Name
Burghardt
mailing address
Texas A&M University; Dean Of Veterinary Medicine; 4461 TAMU
College Station, TX 77843-4461
USA