Scholars

Zhu, Guan

Professor

Positions:

Professor, Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences

Single Page Bio

gzhu@tamu.edu

1 979 845 6981

Co-author Network

Map of Science

overview

Our laboratory conducts translational research with an ultimate goal to discover new anti-parasitic therapeutics by targeting metabolic enzymes and other molecules critical or essential to the parasite infection, survival and development, such as those involved in the lipid and energy metabolisms and interacting with host cells in Cryptosporidium and other protozoan parasites. Other research areas include functional genomics and molecular evolution of apicomplexan parasites, and parasitic diseases important to the conservation of wild animals.

education and training

Wadsworth Center - (Albany, New York, United States), Postdoctoral Training 1996
Ph.D. in Poultry/Parasitology, University of Georgia - (Athens, Georgia, United States) 1993
M.S. in Zoology/Parasitology, Zhejiang University - (Hangzhou, Zhejiang, China) 1986
B.S. in Biology, Zhejiang University - (Hangzhou, Zhejiang, China) 1983

selected publications

Academic Articles67

Yu, X., Hoyle, R. L., Guo, F., Ratliff, C. M., Cantu, V., Crow, J., ... Zhu, G. (2019). A Vavraia-like microsporidium as the cause of deadly infection in threatened and endangered Eurycea salamanders in the United States. Parasites and Vectors. 12(1), 108.
Jin, Z. i., Ma, J., Zhu, G., & Zhang, H. (2019). Discovery of Novel Anti-cryptosporidial Activities From Natural Products by in vitro High-Throughput Phenotypic Screening. Frontiers in Microbiology. 10(AUG), 1999.
Guo, F., Zhang, H., Eltahan, R., & Zhu, G. (2019). Molecular and Biochemical Characterization of a Type II Thioesterase From the Zoonotic Protozoan Parasite Cryptosporidium parvum. Front Cell Infect Microbiol. 9(JUN), 199.
Eltahan, R., Guo, F., Zhang, H., & Zhu, G. (2019). The Action of the Hexokinase Inhibitor 2-deoxy-d-glucose on Cryptosporidium parvum and the Discovery of Activities against the Parasite Hexokinase from Marketed Drugs. JOURNAL OF EUKARYOTIC MICROBIOLOGY. 66(3), 460-468.
Eltahan, R., Guo, F., Zhang, H., Xiang, L., & Zhu, G. (2018). Discovery of ebselen as an inhibitor of Cryptosporidium parvum glucose-6-phosphate isomerase (CpGPI) by high-throughput screening of existing drugs. International Journal for Parasitology: Drugs and Drug Resistance. 8(1), 43-49.

Chapters3

Zhang, H., & Zhu, G. (2020). High-Throughput Screening of Drugs Against the Growth of Cryptosporidium parvum In Vitro by qRT-PCR.. Methods in molecular biology (Clifton, N.J.). Methods in Molecular Biology. (pp. 319-334). Springer New York.
Zhu, G., & Guo, F. (2014). Cryptosporidium Metabolism. Cryptosporidium: Parasite and Disease. (pp. 361-379). Springer Vienna.
Zhu, G. (2009). Energy metabolism and carbon flow in Cryptosporidium parvum. Giardia and Cryptosporidium: From Molecules to Diseases. (pp. 360-368).