overview

Research in my laboratory employs multidisciplinary approaches to study the cellular and molecular neurobiology of cell-autonomous circadian clocks and the signal transduction pathway responsible for circadian photoentrainment. The aims of current projects are to study: 1) the role of microRNAs (miRNAs) and other signaling molecules in the local temporal coordination of cell- and tissue-specific circadian clocks; 2) mutual interactions between the circadian clock mechanism, inflammatory signaling and metabolism; and 3) the mechanisms linking circadian rhythm disruption with metabolic disorders such as obesity and diabetes, and with pathological changes in neuroprotective responses to stroke.

selected publications
Academic Articles63
Chapters1
  • Earnest, D. J. (2010). Circadian Regulation by the Suprachiasmatic Nucleus. Encyclopedia of Neuroscience. (pp. 945-950). Elsevier.
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Conference Papers11
teaching activities
chaired theses and dissertations
Email
dearnest@tamu.edu
First Name
David
Last Name
Earnest
mailing address
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS
College Station, TX 77843-1114
USA