Case, Adam individual record
Associate Professor
overview

Redox signaling is vital for proper immune system function, yet this area of research is understudied. My graduate career focused on the role of mitochondrial superoxide in T-lymphocyte development. I transitioned this expertise into my postdoctoral training where I examined the role of redox signaling in T-lymphocytes during the pathogenesis of cardiovascular disease. As an independent investigator, I have extended this work to identify the contribution of the immune system and redox signaling to different pathological states of psychological trauma and stress. With this, I am investigating the redox, metabolic, and epigenetic mechanisms that may affect immune cell function and potentiate psychological trauma-mediated inflammatory diseases.

selected publications
Academic Articles84
  • Moore, T. A., & Case, A. J. (2022). Cytokine levels throughout the perinatal period.. J Matern Fetal Neonatal Med. 35(25), 5513-5519.
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  • Reed, E., Lauten, T., Clopp, A., Moshfegh, C., Elkhatib, S., & Case, A. (2022). Mitochondrial Regulation of Inflammation after Psychological Trauma. Free Radical Biology and Medicine. 192, 33-34.
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  • Costanzo-Garvey, D. L., Case, A. J., Watson, G. F., Alsamraae, M., Chatterjee, A., Oberley-Deegan, R. E., ... Cook, L. M. (2022). Prostate cancer addiction to oxidative stress defines sensitivity to anti-tumor neutrophils.. Clin Exp Metastasis. 39(4), 641-659.
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  • Rana, S., Kour, S., Kizhake, S., King, H. M., Mallareddy, J. R., Case, A. J., Huxford, T., & Natarajan, A. (2022). Dimers of isatin derived -methylene--butyrolactone as potent anti-cancer agents.. Bioorg Med Chem Lett. 65, 128713-128713.
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  • Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J. (2022). T-lymphocyte tyrosine hydroxylase regulates TH17 T-lymphocytes during repeated social defeat stress.. Brain Behav Immun. 104, 18-28.
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Chapters1
  • Case, A. J., & Domann, F. E. (2009). HypoxiaInduced Gene Regulation through Hypoxia Inducible Factor1. Redox Signaling and Regulation in Biology and Medicine. 207-227. Wiley.
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Conference Papers2
  • Moshfegh, C., Elkhatib, S., Watson, G., & Case, A. (2022). Calprotectin is Protective during Psychological Trauma. FREE RADICAL BIOLOGY AND MEDICINE. 180, 85-85.
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  • Elkhatib, S., Moshfegh, C., Watson, G., & Case, A. (2022). T-Lymphocyte Tyrosine Hydroxylase Regulates IL-17A Downstream of Mitochondrial Superoxide. FREE RADICAL BIOLOGY AND MEDICINE. 180, 81-82.
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Repository Documents / Preprints4
  • Moshfegh, C. M., Elkhatib, S. K., Watson, G. F., Drake, J., Taylor, Z. N., Reed, E. C., ... Case, A. J. (2022). S100a9 Attenuates Inflammation during Repeated Social Defeat Stress.
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  • Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J. (2022). T-lymphocyte Tyrosine Hydroxylase Regulates TH17 T-lymphocytes during Repeated Social Defeat Stress.
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  • Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., Schwab, A. D., Katsurada, K., Patel, K. P., & Case, A. J. (2021). Splenic denervation attenuates repeated social defeat stress-induced T-lymphocyte inflammation.
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Email
acase@tamu.edu
First Name
Adam
Last Name
Case
mailing address
8447 Riverside Pkwy; 3414 MREB2; C/O Adam Case
Bryan, TX 77807
USA