Vemulapalli, Ramesh individual record
Professor and Head

Dr. Vemulapalli's research is primarily focused on the development of recombinant vaccines against infectious diseases. One of the targets of his vaccine research is brucellosis, a bacterial zoonotic disease caused by certain members of the genus Brucella. Brucellosis is a great concern to public health in developing countries due to widespread prevalence of Brucella infections in livestock. In the US, reservoirs of Brucella infections in wildlife, such as bison, elk, and feral swine, continue to pose a threat to livestock industries and human health. The currently available brucellosis veterinary vaccines are neither efficacious in wild animals nor safe for human use. Dr. Vemulapalli has developed novel recombinant vaccine strains that showed dramatically enhanced vaccine efficacy against brucellosis in murine models. Testing these vaccines in domestic and wild animals is a goal of his research program. Research projects in his laboratory are aimed at 1) understanding the pathogenic mechanisms of Brucella species, 2) developing attenuated Brucella strains as vectors to deliver protective proteins of other pathogens and tumors, 3) developing recombinant subunit vaccines to porcine reproductive and respiratory syndrome virus, and 4) development of molecular diagnostics assays for infectious disease investigations.

selected publications
Academic Articles63
  • Drolia, R., Amalaradjou, M., Ryan, V., Tenguria, S., Liu, D., Bai, X., ... Bhunia, A. K. (2020). Receptor-targeted engineered probiotics mitigate lethal Listeria infection.. Nat Commun. 11(1), 6344.
    doi badge pubmed badge
  • Sánchez-Jiménez, M. M., de la Cuesta Zuluaga, J. J., Garcia-Montoya, G. M., Dabral, N., Alzate, J. F., Vemulapalli, R., & Olivera-Angel, M. (2020). Diagnosis of human and canine Brucella canis infection: development and evaluation of indirect enzyme-linked immunosorbent assays using recombinant Brucella proteins.. Heliyon. 6(7), e04393-e04393.
    doi badge pubmed badge
  • doi badge pubmed badge
  • Dabral, N., Jain-Gupta, N., Seleem, M. N., Sriranganathan, N., & Vemulapalli, R. (2015). Overexpression of Brucella putative glycosyltransferase WbkA in B. abortus RB51 leads to production of exopolysaccharide.. Front Cell Infect Microbiol. 5(JUN), 54.
    doi badge pubmed badge
  • Fink, J. M., Moore, G. E., Landau, R., & Vemulapalli, R. (2015). Evaluation of three 5' exonuclease-based real-time polymerase chain reaction assays for detection of pathogenic Leptospira species in canine urine.. J Vet Diagn Invest. 27(2), 159-166.
    doi badge pubmed badge
  • Vemulapalli, R. (2016). Real-Time Reverse Transcription Polymerase Chain Reaction for Rapid Detection of Transmissible Gastroenteritis Virus. Springer Protocols Handbooks. Springer Protocols Handbooks. 115-119. Springer New York.
    doi badge
Conference Papers1
  • Sharma, A., Tandon, M., Ahi, Y. S., Bangari, D. S., Vemulapalli, R., & Mittal, S. K. (2009). Evaluation of Cross-Reactive Humoral and Cell-Mediated Immune Responses among Human, Bovine and Porcine Adenoviruses. MOLECULAR THERAPY. 17, S44-S44.
First Name
Last Name
mailing address
Texas A&M University; Department of Veterinary Pathobiology; 4467 TAMU
College Station, TX 77843-4467