Giles, Erin individual record
Assistant Professor
Positions:
overview

I am currently building a research program that uses an integrative, translational approach to understand the mechanisms by which obesity promotes postmenopausal breast cancers. My work focuses on understanding how the obese microenvironment, when combined with the metabolic and hormonal changes associated with menopause, promote tumor development, survival, and growth. In parallel, I am investigating the role of adipose tissue inflammation in the development of metabolic disease after menopause. My hope is that the knowledge gained from studying the 'normal' adipose and breast environments during menopause will also help us understand the changes that occur to create a tumor-promoting environment in the breast of obese women during this same window of time.

selected publications
Academic Articles23
  • Glenny, E. M., Coleman, M. F., Giles, E. D., Wellberg, E. A., & Hursting, S. D. (2021). Designing Relevant Preclinical Rodent Models for Studying Links Between Nutrition, Obesity, Metabolism, and Cancer. Annual Review of Nutrition. 41(1), 253-282.
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  • Wellberg, E. A., Corleto, K. A., Checkley, L. A., Jindal, S., Johnson, G., Higgins, J. A., ... Giles, E. D. (2021). Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer. bioRxiv. 2021.10.18.464856.
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  • Fabian, C. J., Klemp, J. R., Marchello, N. J., Vidoni, E. D., Sullivan, D. K., Nydegger, J. L., ... Kimler, B. F. (2021). Rapid Escalation of High-Volume Exercise during Caloric Restriction; Change in Visceral Adipose Tissue and Adipocytokines in Obese Sedentary Breast Cancer Survivors. Cancers. 13(19), 4871-4871.
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  • Fabian, C. J., Befort, C. A., Phillips, T. A., Nydegger, J. L., Kreutzjans, A. L., Powers, K. R., ... Kimler, B. F. (2021). Change in Blood and Benign Breast Biomarkers in Women Undergoing a Weight Loss Intervention Randomized to High Dose ω-3 Fatty Acids vs Placebo.. Cancer Prev Res (Phila). 14(9), 893-904.
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  • Giles, E. D., & Wellberg, E. A. (2020). Preclinical Models to Study Obesity and Breast Cancer in Females: Considerations, Caveats, and Tools.. J Mammary Gland Biol Neoplasia. 25(4), 237-253.
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Chapters1
  • Giles, E., & Singh, G. (2005). Role of TGF- and IGF in Tumor Progression and Bone Metastases. Singh, G., & Rabbani, S. A. (Eds.), Bone Metastasis. 59-74. Humana Press.
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Conference Papers15
  • Corleto, K. A., Mahmood, T. N., Landrock, D., Hursting, S. D., Fabian, C. J., Kimler, B. F., & Giles, E. D. (2021). Abstract 2567: Duavee® improves metabolic health without increasing cancer risk: findings from a preclinical model of obesity and postmenopausal breast cancer. Prevention Research, Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. 2567-2567.
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  • Corleto, K. A., Mahmood, T. N., Landrock, D., Hursting, S. D., Fabian, C. J., Kimler, B. F., & Giles, E. D. (2021). Duavee (R) improves metabolic health without increasing cancer risk: findings from a preclinical model of obesity and postmenopausal breast cancer.. CANCER RESEARCH. 81(13),
  • Fabian, C. J., Befort, C. A., Sullivan, D. K., Carlson, S. E., Nydegger, J. L., Kreutzjans, A. L., ... Kimler, B. F. (2021). Abstract PD11-02: Randomized trial of 12 months of omega-3 fatty acids vs placebo during a weight loss intervention in post-menopausal women at increased risk for breast cancer. Poster Spotlight Session Abstracts, Abstracts: 2020 San Antonio Breast Cancer Virtual Symposium; December 8-11, 2020; San Antonio, Texas. pd11-02-pd11-02.
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  • Fabian, C. J., Befort, C. A., Sullivan, D. K., Carlson, S. E., Nydegger, J. L., Kreutzjans, A. L., ... Kimler, B. F. (2021). Randomized trial of 12 months of omega-3 fatty acids vs placebo during a weight loss intervention in post-menopausal women at increased risk for breast cancer. CANCER RESEARCH. 81(4),
  • Sherk, V. D., Dana Carpenter, R., Giles, E. D., Oljira, R., Mills, S., Johnson, G. C., Higgins, J. A., & MacLean, P. S. (2016). Ibuprofen Before Exercise Does Not Alter Cortical Bone Adaptations to Treadmill Running in Female Rats. Medicine & Science in Sports & Exercise. 48(5S), 490-490.
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Email
egiles@tamu.edu
First Name
Erin
Last Name
Giles
mailing address
Texas A&M University; Nutrition; 2253 TAMU
College Station, TX 77843-2253
USA