Glaser, Shannon individual record
Professor
overview

The long-term goal of my research program is to understand how activated (proliferating) cholangiocytes participate in the progression of cholestatic liver diseases and eventual development of cholangiocarcinoma. My research is focused on elucidating the factors (such as, mechanical stress) and intracellular signaling mechanisms that regulate cholangiocyte proliferation and biliary fibrosis during extrahepatic cholestasis.

selected publications
Academic Articles222
  • Ceci, L., Chen, L., Baiocchi, L., Wu, N., Kennedy, L., Carpino, G., ... Glaser, S. (2022). Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model.. Cell Mol Gastroenterol Hepatol. S2352-345X(22)00165-5.
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  • Raggi, C., Fiaccadori, K., Pastore, M., Correnti, M., Piombanti, B., Forti, E., ... Invernizzi, P. (2019). Antitumor Activity of a Novel Fibroblast Growth Factor Receptor Inhibitor for Intrahepatic Cholangiocarcinoma.. Am J Pathol. 189(10), 2090-2101.
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  • Kennedy, L., Francis, H., Invernizzi, P., Venter, J., Wu, N., Carbone, M., ... Alpini, G. (2019). Secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early-stage primary biliary cholangitis.. FASEB J. 33(9), 10269-10279.
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  • McDaniel, K., Wu, N., Zhou, T., Huang, L. i., Sato, K., Venter, J., ... Meng, F. (2019). Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 Knockout Mice via Lethal-7 microRNA.. Hepatology. 69(6), 2562-2578.
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  • Navas, M., Glaser, S., Dhruv, H., Celinski, S., Alpini, G., & Meng, F. (2019). Hepatitis C Virus Infection and Cholangiocarcinoma: An Insight into Epidemiologic Evidences and Hypothetical Mechanisms of Oncogenesis.. Am J Pathol. 189(6), 1122-1132.
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Chapters5
  • Ray, D., Han, Y., Maroni, L., Marzioni, M., Meng, F., Alpini, G., & Glaser, S. (2015). Liver Regeneration. Liver Regeneration. 229-241. Elsevier.
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  • H. Afroze, S., Jensen, K., Rahal, K., Meng, F., Alpini, G., & Glaser, S. S. (2014). Liver Regeneration. Regenerative Medicine Applications in Organ Transplantation. 375-390. Elsevier.
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  • Feng, H., Gerilechaogetu, F., Golden, H. B., Nizamutdinov, D., Foster, D. M., Glaser, S., & Dostal, D. E. (2013). Paracrine communication between mechanically stretched myocytes and fibroblasts. Baudino, T. A. (Eds.), Cell-Cell Interactions: Methods and Protocols. 57-66. Humana Press.
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  • Gerilechaogetu, F., Feng, H., Golden, H. B., Nizamutdinov, D., Foster, D. M., Glaser, S., & Dostal, D. E. (2013). Production of spontaneously beating neonatal rat heart tissue for calcium and contractile studies. Baudino, T. A. (Eds.), Cell-Cell Interactions: Methods and Protocols. 45-56. Humana Press.
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  • LeSage, G. D., Glaser, S. S., Francis, H., Phinizy, J. L., & Alpini, G. (2004). 2. FUNCTIONAL HETEROGENEITY OF INTRAHEPATIC CHOLANGIOCYTES. Principles of Medical Biology. The Liver in Biology and Disease. 21-48. Elsevier.
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Conference Papers2
  • Fava, G., Marzioni, M., Francis, H., Glaser, S., Demorrrow, S., Ueno, Y., Benedetti, A., & Alpini, G. (2007). Novel interaction of bile acid and neural signaling in the regulation of cholangiocyte function.. Hepatol Res. 37 Suppl 3(s3), S420-S429.
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  • Alvaro, D., Alpini, G., Onori, P., Franchitto, A., Glaser, S. S., Le Sage, G., ... Gaudio, E. (2002). Alfa and beta estrogen receptors and the biliary tree.. Mol Cell Endocrinol. 193(1-2), 105-108.
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recent teaching activities
Email
sglaser@tamu.edu
First Name
Shannon
Last Name
Glaser
mailing address
Texas A&M Health Science Center; Internal Medicine - Scott And White; 1114 TAMUS
Temple, TX 76504
USA