Guo, Shaodong
individual record
Associate Professor
Positions:
- Associate Professor, Nutrition and Food Science, College of Agriculture and Life Sciences
overview
The long-term goal of our research is to study the molecular mechanisms of insulin signal transduction, insulin resistance and associated cardiovascular dysfunction, aiming at nutritional and therapeutic intervention for control of metabolic and cardiovascular disorders. My laboratory is focused on the study of cellular signaling and gene transcriptional regulation of metabolic homeostasis that are governed by the PI3K->Akt->FoxO pathway, with the hope of understanding how dysregulation of this pathway in insulin/IGF-1 action causes liver damage, cardiovascular dysfunction, and pancreatic beta cell failure, resulting in diabetes, obesity, and organ failure.
education and training
- Ph.D. in Physiology, Peking University - (Beijing, Beijing, China) 1995
- B.S. in Agronomy, Huazhong Agricultural University - (Wuhan, China) 1989
selected publications
Academic Articles63
- Villarreal, D., Pradhan, G., Wu, C., Allred, C. D., Guo, S., & Sun, Y. (2019). A Simple High Efficiency Protocol for Pancreatic Islet Isolation from Mice.. Journal of visualized experiments : JoVE. (150),
- Liao, X., Song, L., Zeng, B., Liu, B., Qiu, Y., Qu, H., ... Zheng, H. (2019). Alteration of gut microbiota induced by DPP-4i treatment improves glucose homeostasis. EBioMedicine. 44, 665-674.
- Li, X., Chen, Y., Shen, J. Z., Pan, Q., Yang, W., Yan, H., ... Guo, S. (2019). Epigallocatechin Gallate Inhibits Hepatic Glucose Production in Primary Hepatocytes via Downregulating PKA Signaling Pathways and Transcriptional Factor FoxO1. Journal of Agricultural and Food Chemistry. 67(13), 3651-3661.
- Yan, H., Yang, W., Zhou, F., Li, X., Pan, Q., Shen, Z., ... Guo, S. (2019). Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1. DIABETES. 68(2), db180638-304.
- Liu, H., Liu, M., Jin, Z., Yaqoob, S., Zheng, M., Cai, D., Liu, J., & Guo, S. (2019). Ginsenoside Rg2 inhibits adipogenesis in 3T3-L1 preadipocytes and suppresses obesity in high-fat-diet-induced obese mice through the AMPK pathway.. FOOD & FUNCTION. 10(6), 3603-3614.
awards and honors
- Thomas R Lee Awards conferred by American Diabetes Association conferred by American Diabetes Association - (Alexandria, Virginia, United States) 2015
teaching activities
- NFSC475 Nutr & Physiolog Chem Instructor
- NFSC481 Seminar Instructor
- NFSC491 Hnr-research Instructor
- NFSC491 Research Instructor
- NFSC632 Nutrition In Disease Instructor
Email
shaodong.guo@tamu.edu
First Name
Shaodong
Last Name
Guo
mailing address
Texas A&M University; Nutrition & Food Science; 2253 TAMU
College Station, TX 77843-2253
USA