Guo, Shaodong
individual record
Associate Professor and Presidential Impact Fellow
Positions:
- Associate Professor, Nutrition, College of Agriculture and Life Sciences
UN Sustainable Development Goals:
UN Sustainable Development Goals:
overview
The long-term goal of our research is to study the molecular mechanisms of insulin signal transduction, insulin resistance and associated cardiovascular dysfunction, aiming at nutritional and therapeutic intervention for control of metabolic and cardiovascular disorders. My laboratory is focused on the study of cellular signaling and gene transcriptional regulation of metabolic homeostasis that are governed by the PI3K->Akt->FoxO pathway, with the hope of understanding how dysregulation of this pathway in insulin/IGF-1 action causes liver damage, cardiovascular dysfunction, and pancreatic beta cell failure, resulting in diabetes, obesity, and organ failure.
education and training
- Ph.D. in Physiology, Peking University - (Beijing, Beijing, China) 1995
- B.S. in Agronomy, Huazhong Agricultural University - (Wuhan, China) 1989
selected publications
Academic Articles57
- Yang, W., Yan, H., Pan, Q., Shen, J. Z., Zhou, F., Wu, C., Sun, Y., & Guo, S. (2019). Glucagon regulates hepatic mitochondrial function and biogenesis through FOXO1.. J Endocrinol. 241(3), 265-278.
- Villarreal, D., Pradhan, G., Wu, C., Allred, C. D., Guo, S., & Sun, Y. (2019). A Simple High Efficiency Protocol for Pancreatic Islet Isolation from Mice.. J Vis Exp. (150),
- Yan, H., Yang, W., Zhou, F., Li, X., Pan, Q., Shen, Z., ... Guo, S. (2019). Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1.. Diabetes. 68(2), 291-304.
- Zhang, K., Guo, X., Yan, H., Wu, Y., Pan, Q., Shen, J. Z., ... Guo, S. (2019). Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice.. Endocrinology. 160(5), 1333-1347.
- Xu, H., Li, X., Adams, H., Kubena, K., & Guo, S. (2018). Etiology of Metabolic Syndrome and Dietary Intervention.. Int J Mol Sci. 20(1), 128-128.
in the news
researcher on
Principal Investigator4
Co-Principal Investigator1
Investigator2
awards and honors
recent teaching activities
- NFSC475 Nutr & Physiolog Chem Instructor
- NFSC481 Seminar Instructor
- NFSC491 Research Instructor
- NFSC632 Nutrition In Disease Instructor
- NFSC691 Research Instructor
Email
shaodong.guo@tamu.edu
First Name
Shaodong
Last Name
Guo
mailing address
Texas A&M University; Department of Nutrition; 123A-Cater-Mattil Hall; 2253 TAMU
College Station, TX 77843-2253
USA
UN Sustainable Development Goals:
UN Sustainable Development Goals: