Fungal pathogens of cereal crops can cause devastating disruption to the global food supply, and the economic loss due to crop diseases can add up to billions of dollars annually worldwide. The Shim lab at Texas A&M University focused on studying fungal pathogens of field crops, particularly Fusarium species. Notably, hazardous Fusarium mycotoxins pose a significant threat to global food safety and human health. Crop losses as well as the regulatory, testing, and management costs associated with mycotoxins in the US tops $1 billion annually.
The Genus Fusarium has had a great negative impact on agriculture and food safety but also presents a great opportunity for answering many fundamental questions. We are pursuing new discoveries that will ultimately lead to innovative tools for controlling crop diseases and mycotoxin contamination. To broaden the impact, we are actively collaborating with colleagues at Texas A&M as well as other prominent institutions worldwide. We are also very excited about our collaborations with colleagues in Texas A&M Engineering to spearhead multidisciplinary projects that can innovate plant pathology research.
- Yan, H., Huang, J., Zhang, H., & Shim, W. B. (2019). A Rab GTPase protein FvSec4 is necessary for fumonisin B1 biosynthesis and virulence in Fusarium verticillioides.. Curr Genet.
- Yun, Y., Zhou, X., Yang, S., Wen, Y. a., You, H., Zheng, Y., ... Wang, Z. (2019). Fusarium oxysporum f. sp. lycopersici C2H2 transcription factor FolCzf1 is required for conidiation, fusaric acid production, and early host infection.. Curr Genet. 65(3), 773-783.
- Fan, G., Zhang, K., Zhang, J., Yang, J., Yang, X., Hu, Y., ... Lu, G. (2019). The transcription factor FgMed1 is involved in early conidiogenesis and DON biosynthesis in the plant pathogenic fungus Fusarium graminearum. Appl Microbiol Biotechnol. 103(14), 5851-5865.
- Kim, M. S., Zhang, H., & Shim, W. B. (2018). Application of game theory to explore the dynamics of host−pathogen association in phytobiomes. Phytobiomes Journal. 2(3), 111-116.
- Kim, M. S., Zhang, H., Yan, H., Yoon, B., & Shim, W. B. (2018). Characterizing co-expression networks underpinning maize stalk rot virulence in Fusarium verticillioides through computational subnetwork module analyses. SCIENTIFIC REPORTS. 8(1), 8310.
- Sobahi, N., Dai, J., Shim, W. B., & Han, A. (2016). Discrimination of droplets containing single cultured filamentous fungal cell using impedance spectroscopy. 1168-1169.
- Woloshuk, C., Flaherty, J., & Shim, W. B. (2002). Understanding fumonisin biosynthesis through functional genomics studies in Fusarium verticillioides. Mycopathologia. 155(1-2 SPEC), 12.
- Kim, Mansuck (2016-05). Computational Identification of Functional Modules and Hub Genes Involved in Pathogenicity-Associated or Defense Response on Fusarium Verticillioides-Maize Interactions. (Doctoral Dissertation)
- Ortiz, Carlos S (2013-05). Molecular Characterization of MADS-BOX Transcription Factors and Analysis of Field Population Diversity in the Maize Pathogen Fusarium verticillioides. (Doctoral Dissertation)
- Malapi-Wight, Martha Maria (2013-05). The Role of Cys2-His2 Zinc Finger Transcription Factors in Polyol Metabolism, Asexual Development and Fumonisin Biosynthesis in Fusarium verticillioides. (Doctoral Dissertation)
- Shin, Joonhee (2010-05). Characterization of PP2A regulatory B subunits in Fusarium verticillioides. (Master's Thesis)
- Choi, Yoon E (2008-05). Characterizing the regulatory mechanisms in fusarium verticillioides secondary metabolism using functional genomics approaches. (Doctoral Dissertation)