overview

The long-term goal of my laboratory is to understand the molecular basis of pathogenesis of Marek's disease virus (MDV), a potent oncogenic herpesvirus that causes T-cell tumors in chickens. MDV codes for a protein (Meq), which shares significant resemblance with the Jun/Fos family of transcriptional factors. We have shown that this gene plays a critical role in latency and transformation of T-lymphocytes. Understanding the basic mechanism of viral pathogenesis will aid in the development of improved vaccine. We are also interested in other important poultry disease like avian influenza.

selected publications
Academic Articles82
  • Liao, Y., Bajwa, K., Reddy, S. M., & Lupiani, B. (2021). Methods for the Manipulation of Herpesvirus Genome and the Application to Marek's Disease Virus Research.. Microorganisms. 9(6), 1260-1260.
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  • Liao, Y., Fang, X., Ai-Mahmood, M., Li, Q., Lupiani, B., & Reddy, S. M. (2021). US3 Serine/Threonine Protein Kinase from MDV-1, MDV-2, and HVT Differentially Regulate Viral Gene Expression and Replication.. Microorganisms. 9(4), 785-785.
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  • Liao, Y., Lupiani, B., & Reddy, S. M. (2021). Manipulation of Promyelocytic Leukemia Protein Nuclear Bodies by Marek's Disease Virus Encoded US3 Protein Kinase.. Microorganisms. 9(4), 685-685.
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  • Liao, Y., Reddy, S. M., Khan, O. A., Sun, A., & Lupiani, B. (2021). A Novel Effective and Safe Vaccine for Prevention of Marek's Disease Caused by Infection with a Very Virulent Plus (vv+) Marek's Disease Virus.. Vaccines (Basel). 9(2), 159-159.
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Chapters3
  • Lupiani, B. M., Liao, Y., Jin, D. i., Izumiya, Y., & Reddy, S. M. (2019). Marek's Disease Virus. Avian Virology: Current Research and Future Trends. Caister Academic Press.
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  • Schijns, V., van de Zande, S., Lupiani, B., & Reddy, S. M. (2014). Practical Aspects of Poultry Vaccination. Avian Immunology. 345-362. Elsevier.
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  • Schijns, V., van de Zande, S., Lupiani, B., & Reddy, S. M. (2014). Chapter 20 Practical Aspects of Poultry Vaccination. Avian Immunology. 345-362.
Conference Papers6
  • Kayser, W. C., Carstens, G. E., Washbun, K. E., Lawhon, S. D., Reddy, S. M., Skidmore, A. L., Chevaux, E., & Pinchak, W. E. (2018). 101 Effects of Live Yeast Supplementation on Complete Blood Cell Count and Febrile Responses in Heifers after Viral-Bacterial Respiratory Challenge.. Journal of Animal Science. 96(suppl_1), 57-58.
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  • Reddy, S. M., Sun, A., Khan, O. A., Lee, L. F., & Lupiani, B. (2013). Cloning of a Very Virulent Plus, 686 Strain of Marek's Disease Virus as a Bacterial Artificial Chromosome. AVIAN DISEASES. 57(2), 469-473.
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  • Sun, A., Lee, L. F., Khan, O. A., Heidari, M., Zhang, H., Lupiani, B., & Reddy, S. M. (2013). Deletion of Marek's Disease Virus Large Subunit of Ribonucleotide Reductase Impairs Virus Growth In Vitro and In Vivo. AVIAN DISEASES. 57(2), 464-468.
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  • Lupiani, B., Lee, L. F., Kreager, K. S., Witter, R. L., & Reddy, S. M. (2013). Insertion of Reticuloendotheliosis Virus Long Terminal Repeat into the Genome of CVI988 Strain of Marek's Disease Virus Results in Enhanced Growth and Protection. AVIAN DISEASES. 57(2), 427-431.
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patents
Patents3
Email
sreddy@tamu.edu
First Name
Sanjay
Last Name
Reddy
mailing address
Texas A&M University; Vet Med Pathobiology; 4467 TAMU
College Station, TX 77843-4467
USA