Scholars

Professor

Positions:

Professor, Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences

overview

The long-term goal of my laboratory is to understand the molecular basis of pathogenesis of Marek's disease virus (MDV), a potent oncogenic herpesvirus that causes T-cell tumors in chickens. MDV codes for a protein (Meq), which shares significant resemblance with the Jun/Fos family of transcriptional factors. We have shown that this gene plays a critical role in latency and transformation of T-lymphocytes. Understanding the basic mechanism of viral pathogenesis will aid in the development of improved vaccine. We are also interested in other important poultry disease like avian influenza.

education and training

Ph.D. in Molecular Virology, University of Maryland, College Park - (College Park, Maryland, United States) 1994
M.S. in Virology, University of Maryland, College Park - (College Park, Maryland, United States) 1989
D.V.M. in Veterinary Medicine, Andhra University - (Visakhapatnam, Andhra Pradesh, India) 1986

selected publications

Academic Articles85

Liao, Y., Lupiani, B., Ai-Mahmood, M., & Reddy, S. M. (2021). Marek's disease virus US3 protein kinase phosphorylates chicken HDAC 1 and 2 and regulates viral replication and pathogenesis.. PLoS Pathogens. 17(2), e1009307-e1009307.
Liao, Y., Bajwa, K., Al-Mahmood, M., Gimeno, I. M., Reddy, S. M., & Lupiani, B. (2021). The role of Meq-vIL8 in regulating Marek's disease virus pathogenesis.. JOURNAL OF GENERAL VIROLOGY. 102(2),
Liao, Y., Reddy, S. M., Khan, O. A., Sun, A., & Lupiani, B. (2021). A Novel Effective and Safe Vaccine for Prevention of Marek's Disease Caused by Infection with a Very Virulent Plus (vv+) Marek's Disease Virus.. Vaccines. 9(2), 159-159.
Liao, Y., Lupiani, B., & Reddy, S. M. (2021). Latest Insights into Unique Open Reading Frames Encoded by Unique Long (UL) and Short (US) Regions of Marek's Disease Virus.. Viruses. 13(6), 974-974.
Liao, Y., Lupiani, B., & Reddy, S. M. (2021). Manipulation of Promyelocytic Leukemia Protein Nuclear Bodies by Marek's Disease Virus Encoded US3 Protein Kinase.. Microorganisms. 9(4), 685-685.

Chapters3

Lupiani, B. M., Liao, Y., Jin, D. i., Izumiya, Y., & Reddy, S. M. (2019). Marek's Disease Virus. Avian Virology: Current Research and Future Trends. Caister Academic Press.
Schijns, V., van de Zande, S., Lupiani, B., & Reddy, S. M. (2014). Practical Aspects of Poultry Vaccination. Avian Immunology. 345-362. Elsevier.

SDG 3
Schijns, V., van de Zande, S., Lupiani, B., & Reddy, S. M. (2014). Chapter 20 Practical Aspects of Poultry Vaccination. Avian Immunology. 345-362. Elsevier.

SDG 3