Mabbott, Samuel individual record
Assistant Professor

Dr. Mabbott's research focuses on the development of metallic nanoparticles for use in biomedical devices and healthcare settings. Applications include: integration into point of care devices for sensitive detection of disease relevant biomolecules such as circulating miRNA; controlling the nanoparticles light-to-heat conversion (photothermal) efficiency for destruction of diseased tissues (eg. Tumors); localized delivery of miRNA for gene therapy; increasing the therapeutic effect of drugs; biological and chemical signal amplification.

education and training
selected publications
Academic Articles27
  • San Juan, A., Chavva, S. R., Tu, D., Tircuit, M., Coté, G., & Mabbott, S. (2021). Synthesis of SERS-active core–satellite nanoparticles using heterobifunctional PEG linkers. Nanoscale Advances. 4(1), 258-267.
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  • Girard, A., Cooper, A., Mabbott, S., Bradley, B., Asiala, S., Jamieson, L., ... Graham, D (2021). Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis. PLOS Pathogens. 17(11), e1010060-e1010060.
  • Tu, D., Holderby, A., Dean, J., Mabbott, S., & Coté, G. L. (2021). Paper Microfluidic Device with a Horizontal Motion Valve and a Localized Delay for Automatic Control of a Multistep Assay.. Anal Chem. 93(10), 4497-4505.
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  • Mabbott, S., Fernandes, S. C., Schechinger, M., Cote, G. L., Faulds, K., Mace, C. R., & Graham, D (2020). Detection of cardiovascular disease associated miR-29a using paper-based microfluidics and surface enhanced Raman scattering.. Analyst. 145(3), 983-991.
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  • Schechinger, M., Marks, H., Mabbott, S., Choudhury, M., & Cote', G (2019). A SERS approach for rapid detection of microRNA-17 in the picomolar range.. Analyst. 144(13), 4033-4044.
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  • Asiala, S., Barrett, L., Mabbott, S., & Graham, D (2016). Advances in Biofunctional SERS-Active Nanoparticles for Future Clinical Diagnostics and Therapeutics. PHYTOREMEDIATION OF SOIL AND WATER CONTAMINANTS. ACS Symposium Series. 131-161. AMERICAN CHEMICAL SOCIETY.
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Conference Papers8
  • Jaitpal, S., Chavva, S., & Mabbott, S (2021). Towards point-of-care detection of microRNAs using paper-based microfluidics. Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics, Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics. 11651, 116510c-116510c-6.
  • Sengupta, S., Bedics, M., Plakas, K., Bromley, L., Kearns, H., Mabbott, S., ... Velarde, L (2016). Orientation and binding of near infrared absorbing dyes at a gold surface. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 252,
  • Heydari, E., Mabbott, S., Thompson, D., Graham, D., Cooper, J. M., & Clark, A. W (2016). Engineering molecularly-active nanoplasmonic surfaces for DNA detection via colorimetry and Raman scattering. Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII, SPIE BiOS. 9721, 972105-972105-6.
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  • Marks, H., Mabbott, S., Huang, P., Jackson, G. W., Kameoka, J., Graham, D., & Cot, G. L. (2016). Comparison of Fe2O3and Fe2CoO4core-shell plasmonic nanoparticles for aptamer mediated SERS assays. SPIE Proceedings, SPIE BiOS. 9722, 97220n-97220n-8.
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  • Hayes, M., Graham, D., & Mabbott, S (2016). Investigation of surface enhanced Raman scattering activity in silver-coated magnetic nanoparticles. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 251,
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