overview

Research in my laboratory focuses on better understanding the molecular mechanisms of pathogenesis of Marek's disease virus, a chicken oncogenic alphaherpesvirus. We study gene function using biochemical techniques and by introducing mutations into the viral genome. The knowledge obtained from these studies is used to develop vaccines to control this critical poultry pathogen. In addition, we are investigating the use of Marek's disease vaccines as viral vectors to control other viral diseases of poultry.

selected publications
Academic Articles89
  • Carter, R. G., Mundorff, K., Risien, J., Bouwma-Gearhart, J., Bratsch-Prince, D., Brown, S. A., ... Van Egeren, L. (2021). Innovation, entrepreneurship, promotion, and tenure. Science. 373(6561), 1312-1314.
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  • Liao, Y., Bajwa, K., Reddy, S. M., & Lupiani, B. (2021). Methods for the Manipulation of Herpesvirus Genome and the Application to Marek's Disease Virus Research.. Microorganisms. 9(6), 1260-1260.
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  • Liao, Y., Fang, X., Ai-Mahmood, M., Li, Q., Lupiani, B., & Reddy, S. M. (2021). US3 Serine/Threonine Protein Kinase from MDV-1, MDV-2, and HVT Differentially Regulate Viral Gene Expression and Replication.. Microorganisms. 9(4), 785-785.
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  • Liao, Y., Lupiani, B., & Reddy, S. M. (2021). Manipulation of Promyelocytic Leukemia Protein Nuclear Bodies by Marek's Disease Virus Encoded US3 Protein Kinase.. Microorganisms. 9(4), 685-685.
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Chapters3
  • Lupiani, B. M., Liao, Y., Jin, D. i., Izumiya, Y., & Reddy, S. M. (2019). Marek's Disease Virus. Avian Virology: Current Research and Future Trends. Caister Academic Press.
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  • Schijns, V., van de Zande, S., Lupiani, B., & Reddy, S. M. (2014). Chapter 20 Practical Aspects of Poultry Vaccination. Avian Immunology. 345-362. Elsevier.
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  • Schijns, V., van de Zande, S., Lupiani, B., & Reddy, S. M. (2014). Practical Aspects of Poultry Vaccination. Avian Immunology. 345-362. Elsevier.
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Conference Papers7
  • Reddy, S. M., Sun, A., Khan, O. A., Lee, L. F., & Lupiani, B. (2013). Cloning of a Very Virulent Plus, 686 Strain of Marek's Disease Virus as a Bacterial Artificial Chromosome. AVIAN DISEASES. 57(2), 469-473.
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  • Sun, A., Lee, L. F., Khan, O. A., Heidari, M., Zhang, H., Lupiani, B., & Reddy, S. M. (2013). Deletion of Marek's Disease Virus Large Subunit of Ribonucleotide Reductase Impairs Virus Growth In Vitro and In Vivo. AVIAN DISEASES. 57(2), 464-468.
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  • Lupiani, B., Lee, L. F., Kreager, K. S., Witter, R. L., & Reddy, S. M. (2013). Insertion of Reticuloendotheliosis Virus Long Terminal Repeat into the Genome of CVI988 Strain of Marek's Disease Virus Results in Enhanced Growth and Protection. AVIAN DISEASES. 57(2), 427-431.
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  • Echevarria, M., Ferro, P., Vuong, C., Metz, K., Hogan, M., & Lupiani, B. (2013). Investigation of the utility of the Simport‐Matrix Chaperones for Avian Influenza Virus sample storage and transportation. The FASEB Journal. 27(S1), 874.17-874.17.
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in the news
patents
Patents5
  • Reddy, S. M., & Lupiani, B. M. (2020). Recombinant turkey herpesvirus vaccines and uses thereof.
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  • Reddy, S. M., & Lupiani, B. M. (2020). Recombinant turkey herpesvirus vaccines and uses thereof.
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  • Reddy, S. M., & Lupiani, B. M. (2010). Marek's disease virus vaccine.
  • Reddy, S. M., & Lupiani, B. M. (2007). Marek's disease virus vaccine.
recent teaching activities
chaired theses and dissertations
Email
blupiani@tamu.edu
First Name
Blanca
Last Name
Lupiani
mailing address
Texas A&M University; Department of Veterinary Pathobiology; 4467 TAMU
College Station, TX 77843-4467
USA