- Professor and Director, Center For Biomedical Informatics, Texas A&M Clinical Science and Translational Research Institute
My research program focuses on brain-immune interactions regulated by estrogen and its implications for neuro-inflammatory diseases such as stroke in women. Additionally, I am also interested in estrogens interactions with other endogenous and environmental endocrine mediators, including Vitamin D hormone and the peptide hormone Insulin-like Growth Factor (IGF)-1. Our current studies use an animal model to examine age and sex differences in recovery from stroke, focusing at the cellular level on the endothelium and astrocytes, which are the principal components of the blood brain barrier. At the molecular level, we are examining sex and age differences in miRNA and epigenetic markers, with a view to developing biomarkers for diseases and uncovering new therapeutic targets.
- Ph.D. in Computer and Information Science, The Ohio State University - (Columbus, Ohio, United States) 1986
- The Ohio State University - (Columbus, Ohio, United States), Postdoctoral Training 1985
- The Ohio State University - (Columbus, Ohio, United States), Medical Residency 1981
- M.S. in Computer and Information Science, The Ohio State University - (Columbus, Ohio, United States) 1980
- M.D. in Medicine, West Virginia University - (Morgantown, West Virginia, United States) 1977
- B.S. in Physics, Virginia Tech - (Blacksburg, Virginia, United States) 1973
- Zozus, M. N., Pieper, C., Johnson, C. M., Johnson, T. R., Franklin, A., Smith, J., & Zhang, J. (2015). Factors affecting accuracy of data abstracted from medical records. PLoS ONE. 10(10), e0138649-e0138649.
- Sun, Y., O'Reilly, R. C., Bhattacharyya, R., Smith, J. W., Liu, X., & Wang, H. (2015). Latent structure in random sequences drives neural learning toward a rational bias. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES. 112(12), 3788-3792.
- Sun, Y., O'Reilly, R. C., Smith, J. W., & Wang, H. (2015). Reply to Aksentijevic: It is a matter of what is countable and how neurons learn. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES. 112(25), E3160-E3160.
- Kulikowski, C. A., Shortliffe, E. H., Currie, L. M., Elkin, P. L., Hunter, L. E., Johnson, T. R., ... Williamson, J. J. (2012). AMIA Board white paper: definition of biomedical informatics and specification of core competencies for graduate education in the discipline. Journal of the American Medical Informatics Association. 19(6), 931-938.
- Stead, W. W., Searle, J. R., Fessler, H. E., Smith, J. W., & Shortliffe, E. H. (2011). Biomedical Informatics: Changing What Physicians Need to Know and How They Learn. Acad Med. 86(4), 429-434.
- Guerlain, S., Smith, P. J., Smith, J. W., Rudmann, S., Obradovich, J. H., & Strohm, P. (2018). Decision support in medical systems. Automation and Human Performance: Theory and Applications. (pp. 385-406). Routledge.
- Iyengar, M. S., Svirbeiy, J. R., Rusu, M., & Smith, J. W. (2008). VITA - An interactive 3-D visualization system to enhance student understanding of mathematical concepts in medical decision-making. PROCEEDINGS OF THE 21ST IEEE INTERNATIONAL SYMPOSIUM ON COMPUTER-BASED MEDICAL SYSTEMS. 434- .
- Mirhaji, P., Zhang, J., Srinivasan, A., Richesson, R. L., & Smith, J. W. (2004). Knowledge based public health situation awareness. MATHEMATICAL MODELING AND ESTIMATION TECHNIQUES IN COMPUTER VISION. 5403(PART 1), 198-209.
- Mirhaji, P., Richesson, R. L., Turley, J. P., Zhang, J., & Smith, J. W. (2004). Public health situation awareness, towards a semantic approach. MATHEMATICAL MODELING AND ESTIMATION TECHNIQUES IN COMPUTER VISION. 5434, 339-350.
- Mirhaji, P., Zhang, J., Smith, J. W., Madjid, M., Casscells, S. W., & Lillibridge, S. R. (2003). Informatics Critical to Public Health Surveillance. MATHEMATICAL MODELING AND ESTIMATION TECHNIQUES IN COMPUTER VISION. 5071, 151-163.
- Kantor, G., Svirbely, J. R., Johnson, K., Sriram, M., Rodriguez, J. R., & Smith, J. (2001). MEDAL: The medical algorithm project. MEDINFO 2017: PRECISION HEALTHCARE THROUGH INFORMATICS. 84, 298.