- Clinical Assistant Professor, Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences
I am an anatomic veterinary pathologist from Bern, Switzerland with broad experience in macroscopical and histological evaluation of tissues from various animal species. I am specialized in Dermatopathology and I provide diagnostic service in the Dermatopathology Speciality Service as well as diagnostic service to the Veterinary Medical Teaching Hospital at TAMU. My research focuses on understanding the pathogenesis of non-inflammatory alopecia in dogs. I am investigating the molecular pathways involved in the activation of follicular stem cells and the regulation of the hair cycle. Our research group in Bern could establish a method to investigate the colony forming capacity of canine follicular stem cells and transit amplifying cells. In Utrecht, The Netherlands, I established the culturing of canine skin organoids (derived from interfollicular epidermis and hair follicles). This model system recapitulates in vitro skin stratification more faithfully than currently used 2D lines. These organoid lines provide the basis to explore epidermal function, to investigate culture conditions necessary for the development of organoids with a HF signature and to address cutaneous disorders in dogs and potentially human patients.
- Kochat, V., Raman, A. T., Landers, S. M., Tang, M., Schulz, J., Terranova, C., ... Torres, K. E. (2021). Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state. Acta Neuropathologica. 142(3), 565-590.
- Wiener, D. J. (2021). Histologic features of hair follicle neoplasms and cysts in dogs and cats: a diagnostic guide. Journal of Veterinary Diagnostic Investigation. 33(3), 479-497.
- Simpson, A. C., & Wiener, D. J. (2021). Positive effects of hyperbaric oxygen therapy in a cat with cutaneous nocardiosis. Veterinary Dermatology. 32(4), 392-e112.
- Wiener, D. J., Studer, I. C., Brunner, M., Hermann, A., Vincenti, S., Zhang, M., Groch, K. R., & Welle, M. M. (2020). Characterization of canine epidermal organoid cultures by immunohistochemical analysis and quantitative PCR. Veterinary Dermatology. 32(2), 179-e44.
- Milliron, S. M., Seyler, Z. G., Myers, A. N., Hoffmann, A. R., Hnot, M., & Wiener, D. J. (2020). Pyogranulomatous panniculitis in a domestic cat associated with Pseudomonas luteola infection. Veterinary Dermatology. 32(1), 83-e15.
- Veterinary Medical Teaching Hospital (VMTH) Clinical Service Award conferred by Texas A&M University - (College Station, Texas, United States) - Veterinary Medicine & Biomedical Sciences 2019
- Dechra Prize Award conferred by European Society of Veterinary Dermatology - (Maastricht, Netherlands) - Best Laboratory Research (Junior Investigator) 2014