Grunlan, Melissa
individual record
Professor
Positions:
- Professor, Biomedical Engineering, College of Engineering
- Professor, Chemistry, College of Arts and Sciences
- Professor, Materials Science and Engineering, College of Engineering
overview
Prof. Grunlan's research is focused on the development of polymeric biomaterials for medical devices having resistance to biological adhesion and for implantable scaffolds used in regenerative engineering. The unique properties of these biomaterials afford the opportunity to overcome barriers associated with treating various diseases and medical conditions. Specifically, her research has focused on materials for implanted glucose biosensor membranes [to extend sensor lifetime], hemodialysis catheters [to reduce clotting and infection rates], self-fitting tissue scaffolds [to heal bone defects due to injury, tumor resection or congenital birth defect] and cartilage resurfacing [as an alternative to total joint replacement].
education and training
- Ph.D. in Chemistry, University of Southern California - (Los Angeles, California, United States) 2004
- M.S. in Polymers & Coatings, North Dakota State University - (Fargo, North Dakota, United States) 1997
- B.S. in Chemistry, North Dakota State University - (Fargo, North Dakota, United States) 1995
selected publications
Academic Articles119
- Roberts, C. T., Beck, S. K., Prejean, C. M., Graul, L. M., Maitland, D. J., & Grunlan, M. A. (2024). Star-PCL shape memory polymer (SMP) scaffolds with tunable transition temperatures for enhanced utility.. Journal of Materials Chemistry B.
- Nitschke, B. M., Beltran, F. O., Hahn, M. S., & Grunlan, M. A. (2024). Trends in bioactivity: inducing and detecting mineralization of regenerative polymeric scaffolds.. Journal of Materials Chemistry B.
- Ganabady, K., Contessi Negrini, N., Scherba, J. C., Nitschke, B. M., Alexander, M. R., Vining, K. H., ... Celiz, A. D. (2023). High-Throughput Screening of Thiol-ene Click Chemistries for Bone Adhesive Polymers.. ACS Applied Materials & Interfaces. 15(44), 50908-50915.
- Beltran, F. O., Arabiyat, A. S., Culibrk, R. A., Yeisley, D. J., Houk, C. J., Hicks, A. J., ... Grunlan, M. A. (2023). Enhanced degradation and bioactivity in polysiloxane-based shape memory polymer (SMP) scaffolds. Polymer. 284, 126291-126291.
- Demott, C. J., Jones, M. R., Chesney, C. D., & Grunlan, M. A. (2023). Adhesive Hydrogel Building Blocks to Reconstruct Complex Cartilage Tissues.. ACS Biomaterial Science and Engineering. 9(4), 1952-1960.
Books1
- Grunlan, M. A., Xing, L. L., & Glass, J. E. (1997). Waterborne coatings with an emphasis on synthetic aspects: An overview. AMERICAN CHEMICAL SOCIETY.
Chapters1
- Rufin, M. A., & Grunlan, M. A. (2015). Surface-Grafted Polymer Coatings: Preparation, Characterization, and Antifouling Behavior. FUNCTIONAL POLYMER COATINGS: PRINCIPLES, METHODS AND APPLICATIONS. 218-238. Wiley.
Conference Papers46
- Stukel, J. M., Macaitis, J., Chen, W., Botts, E., Grunlan, M. A., Lien, W., & Burdette, A. J. (2019). EVALUATION OF MESENCHYMAL STROMAL CELL DIFFERENTIATION FOR HEALING OF LARGE TISSUE DEFECTS. Shock. 51(6), 162-163.
- Colvin, L. E., Dong, P., Means, A. K., Grunlan, M. A., & Cote, G. L. (2019). Assessment of wavelengths with skin tones for an implantable FRET-based glucose biosensor. Proceedings of SPIE, Optical Diagnostics and Sensing XIX: Toward Point-of-Care Diagnostics. 10885, 108850y-108850y-7.
- Pfau, M. R., McKinzey, K. G., Roth, A. A., & Grunlan, M. A. (2019). Biodegradable shape memory polymer (Smp) semi-interpenetrating networks (semi-ipns) with highly tunable properties for bone regeneration. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium. 40, 219.
- Beltran, F. O., Houk, C. J., & Grunlan, M. A. (2019). Silicon-containing shape memory polymer (Smp) scaffolds for cranial bone defect repair. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium. 40, 495.
- Dong, P., Means, A. K., Schott, B. J., Cot, G. L., & Grunlan, M. A. (2019). Thermoresponsive hydrogels with comb-type architecture for "self-cleaning" glucose biosensor membranes. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium. 40, 758.
Repository Documents / Preprints1
- Yang, F., Kazi, A., Marmo, A., Grunlan, M. A., & Tai, B. L. (2022). Characterizing the Separation Behavior of Photocurable Polydimethylsiloxane on a Hydrogel Film in Vat Photopolymerization: A Benchmark Study.
in the news
- Researchers give $3.6M grant to continuously monitor blood pressure during sleep EurekAlert! July 8, 2020
patents
Patents4
- Grunlan, M. A., Cote, G. L., Abraham, A. A., Fei, R., & Locke, A. K. (2023). Self-cleaning membrane for medical devices.
- Grunlan, M. A., Hahn, M. S., & Saunders, W. B. (2020). Implant-based repair of osteochondral defects.
- Grunlan, M., Zhang, D., Schoener, C., & Saunders, W. (2018). Shape memory polymer scaffolds for tissue defects.
researcher on
Principal Investigator9
Co-Principal Investigator2
Investigator2
Collaborator3
awards and honors
recent teaching activities
- BIOT685 Directed Studies Instructor
- BMEN285 Directed Studies Instructor
- BMEN291 Hnr-research Instructor
- BMEN291 Research Instructor
- BMEN343 Bmen Materials Instructor
chaired theses and dissertations
- Post, Allison Davis (2018-08). Development of a Multilayer Vascular Graft with Targeted Cellular Interactions and Improved Mechanical Properties. (Doctoral Dissertation)
- Woodard, Lindsay Nicole (2018-05). Degradable PCL-PLLA Semi-Interpenetrating Network (Semi-IPN) Shape Memory Polymer (SMP) Scaffolds for Cranial Bone Defect Repair. (Doctoral Dissertation)
- Rufin, Marc Albert (2015-10). PEO-Silane Amphiphiles as Surface-Modifying Additives to Improve the Protein Resistance of Silicone. (Doctoral Dissertation)
- Abraham, Alexander Anil (2015-05). Development of an Encapsulation Strategy for an Implantable Optical Glucose Sensing Technology Compatible with a Self-Cleaning Membrane. (Doctoral Dissertation)
- Hawkins, Melissa Leanne (2014-12). Antifouling Silicone Coatings Prepared with PEO-Silane Amphiphiles. (Doctoral Dissertation)
Email
mgrunlan@tamu.edu
First Name
Melissa
Last Name
Grunlan
mailing address
Texas A&M University; Biomedical Engineering; 3120 TAMU
College Station, TX 77843-3120
USA