overview

Prof. Grunlan's research is focused on the development of polymeric biomaterials for medical devices having resistance to biological adhesion and for implantable scaffolds used in regenerative engineering. The unique properties of these biomaterials afford the opportunity to overcome barriers associated with treating various diseases and medical conditions. Specifically, her research has focused on materials for implanted glucose biosensor membranes [to extend sensor lifetime], hemodialysis catheters [to reduce clotting and infection rates], self-fitting tissue scaffolds [to heal bone defects due to injury, tumor resection or congenital birth defect] and cartilage resurfacing [as an alternative to total joint replacement].

selected publications
Academic Articles119
  • Roberts, C. T., Beck, S. K., Prejean, C. M., Graul, L. M., Maitland, D. J., & Grunlan, M. A. (2024). Star-PCL shape memory polymer (SMP) scaffolds with tunable transition temperatures for enhanced utility.. Journal of Materials Chemistry B.
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  • Nitschke, B. M., Beltran, F. O., Hahn, M. S., & Grunlan, M. A. (2024). Trends in bioactivity: inducing and detecting mineralization of regenerative polymeric scaffolds.. Journal of Materials Chemistry B.
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  • Ganabady, K., Contessi Negrini, N., Scherba, J. C., Nitschke, B. M., Alexander, M. R., Vining, K. H., ... Celiz, A. D. (2023). High-Throughput Screening of Thiol-ene Click Chemistries for Bone Adhesive Polymers.. ACS Applied Materials & Interfaces. 15(44), 50908-50915.
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  • Beltran, F. O., Arabiyat, A. S., Culibrk, R. A., Yeisley, D. J., Houk, C. J., Hicks, A. J., ... Grunlan, M. A. (2023). Enhanced degradation and bioactivity in polysiloxane-based shape memory polymer (SMP) scaffolds. Polymer. 284, 126291-126291.
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  • Demott, C. J., Jones, M. R., Chesney, C. D., & Grunlan, M. A. (2023). Adhesive Hydrogel Building Blocks to Reconstruct Complex Cartilage Tissues.. ACS Biomaterial Science and Engineering. 9(4), 1952-1960.
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Books1
  • Grunlan, M. A., Xing, L. L., & Glass, J. E. (1997). Waterborne coatings with an emphasis on synthetic aspects: An overview. AMERICAN CHEMICAL SOCIETY.
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Chapters1
  • Rufin, M. A., & Grunlan, M. A. (2015). Surface-Grafted Polymer Coatings: Preparation, Characterization, and Antifouling Behavior. FUNCTIONAL POLYMER COATINGS: PRINCIPLES, METHODS AND APPLICATIONS. 218-238. Wiley.
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Conference Papers46
  • Stukel, J. M., Macaitis, J., Chen, W., Botts, E., Grunlan, M. A., Lien, W., & Burdette, A. J. (2019). EVALUATION OF MESENCHYMAL STROMAL CELL DIFFERENTIATION FOR HEALING OF LARGE TISSUE DEFECTS. Shock. 51(6), 162-163.
  • Colvin, L. E., Dong, P., Means, A. K., Grunlan, M. A., & Cote, G. L. (2019). Assessment of wavelengths with skin tones for an implantable FRET-based glucose biosensor. Proceedings of SPIE, Optical Diagnostics and Sensing XIX: Toward Point-of-Care Diagnostics. 10885, 108850y-108850y-7.
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  • Pfau, M. R., McKinzey, K. G., Roth, A. A., & Grunlan, M. A. (2019). Biodegradable shape memory polymer (Smp) semi-interpenetrating networks (semi-ipns) with highly tunable properties for bone regeneration. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium. 40, 219.
  • Beltran, F. O., Houk, C. J., & Grunlan, M. A. (2019). Silicon-containing shape memory polymer (Smp) scaffolds for cranial bone defect repair. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium. 40, 495.
  • Dong, P., Means, A. K., Schott, B. J., Cot, G. L., & Grunlan, M. A. (2019). Thermoresponsive hydrogels with comb-type architecture for "self-cleaning" glucose biosensor membranes. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium. 40, 758.
Repository Documents / Preprints1
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patents
Patents4
  • Grunlan, M. A., & Neans, A. K. (2023). Cartilage mimetic gels.
  • Grunlan, M. A., Cote, G. L., Abraham, A. A., Fei, R., & Locke, A. K. (2023). Self-cleaning membrane for medical devices.
  • Grunlan, M. A., Hahn, M. S., & Saunders, W. B. (2020). Implant-based repair of osteochondral defects.
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  • Grunlan, M., Zhang, D., Schoener, C., & Saunders, W. (2018). Shape memory polymer scaffolds for tissue defects.
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researcher on
chaired theses and dissertations
Email
mgrunlan@tamu.edu
First Name
Melissa
Last Name
Grunlan
mailing address
Texas A&M University; Biomedical Engineering; 3120 TAMU
College Station, TX 77843-3120
USA