Cruz-Reyes, Jorge individual record

We combine approaches in molecular genetics, structural biology, biochemistry, proteomics, and bioinformatics to study the amazing RNA biology of trypanosome parasites. One research line is on an RNA editing process by uridine insertion and deletion that creates amino acid coding triplets in most mRNAs. Yet a single error in the U-changes yields a frame-shift. Trypanosomes split from other eukaryotic lineages over a hundred million years ago, yet this editing has analogies with RNAi, CRISPR/Cas9, mRNA splicing and other systems directed by small non-coding RNAs (ncRNAs).

selected publications
Academic Articles38
  • Cruz‐Reyes, J., & Hernandez, A. (2008). Protein–Protein and RNA–Protein Interactions in U‐Insertion/Deletion RNA Editing Complexes. RNA and DNA Editing. (pp. 71-98). John Wiley & Sons, Inc..
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  • Spice, W. M., Cruz-Reyes, J. A., & Ackers, J. P. (1992). Entamoeba histolytica. Molecular and Cell Biology of Human Diseases Series. Molecular and Cell Biology of Opportunistic Infections in AIDS. (pp. 95-137). Springer Netherlands.
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chaired theses and dissertations
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Texas A&M University; Biochemistry & Biophysics; 2128 TAMU
College Station, TX 77843-2128