overview

My research is focused on fetal brain development, stem cells, microRNAs, and teratology. Our laboratory is interested in understanding the biological steps that transform uncommitted stem cells into neurons or a glial cells, and identifying key microRNAs that control the transformation of stem cells into neurons. We are also currently investigating what role teratogen-sensitive microRNAs play in fetal brain growth, and the spatial patterning of the emerging forebrain.

education and training
selected publications
Academic Articles97
  • Strain, M. M., Johnston, D. T., Baine, R. E., Reynolds, J. A., Huang, Y., Henwood, M. K., ... Grau, J. W. (2021). Hemorrhage and Locomotor Deficits Induced by Pain Input after Spinal Cord Injury Are Partially Mediated by Changes in Hemodynamics. Journal of Neurotrauma. 38(24), 3406-3430.
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  • Bake, S., Pinson, M. R., Pandey, S., Chambers, J. P., Mota, R., Fairchild, A. E., Miranda, R. C., & Sohrabji, F. (2021). Prenatal alcohol-induced sex differences in immune, metabolic and neurobehavioral outcomes in adult rats. Brain, Behavior, and Immunity. 98, 86-100.
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  • Pinson, M. R., Chung, D. D., Adams, A. M., Scopice, C., Payne, E. A., Sivakumar, M., & Miranda, R. C. (2021). Extracellular Vesicles in Premature Aging and Diseases in Adulthood Due to Developmental Exposures. Aging and disease. 12(6), 1516-1516.
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  • Chung, D. D., Pinson, M. R., Bhenderu, L. S., Lai, M. S., Patel, R. A., & Miranda, R. C. (2021). Toxic and Teratogenic Effects of Prenatal Alcohol Exposure on Fetal Development, Adolescence, and Adulthood. International Journal of Molecular Sciences. 22(16), 8785-8785.
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  • Pinson, M. R., Holloway, K. N., Douglas, J. C., Kane, C., Miranda, R. C., & Drew, P. D. (2021). Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period.. Alcohol Clin Exp Res. 45(7), 1408-1423.
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Chapters10
  • Mahnke, A. H., Miranda, R. C., & Mooney, S. M. (2020). Fetal alcohol spectrum disorders. Neurodevelopmental Disorders. 159-178. Elsevier.
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  • Mahnke, A. H., Salem, N. A., Tseng, A. M., Fincher, A. S., Klopfer, A., & Miranda, R. C. (2018). Fetal Alcohol Spectrum Disorders: A Stem-Cellopathy?. Stem Cells in Birth Defects Research and Developmental Toxicology. 223-259. John Wiley & Sons, Inc.
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  • Tseng, A. M., Mahnke, A. H., Salem, N. A., & Miranda, R. C. (2018). Noncoding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation. Epigenetics in Human Disease. 903-933. Elsevier.
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  • Miranda, R. C., Salem, N. A., Fincher, A. S., Mahnke, A. H., & Burrowes, S. G. (2016). Epigenetic Mechanisms and Inheritance of Acquired Susceptibility to Disease. Medical Epigenetics. 531-552. Elsevier.
  • Miranda, R. C., Salem, N. A., Fincher, A. S., Mahnke, A. H., & Burrowes, S. G. (2016). Chapter 30 Epigenetic Mechanisms and Inheritance of Acquired Susceptibility to Disease. Medical Epigenetics. 531-552.
Conference Papers10
  • Salem, N. A., Mahnke, A. H., Konganti, K., Hillhouse, A. E., & Miranda, R. C. (2021). CELL-TYPE AND SEX-SPECIFIC TARGETS OF PRENATAL ALCOHOL EXPOSURE IN THE DEVELOPING MOUSE CEREBRAL CORTEX: IDENTIFICATION OF NOVEL MECHANISMS FOR TERATOGENESIS. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 45, 99A-99A.
  • Mahnke, A. H., Pinson, M. R., Tseng, A. M., Wells, A. B., Chambers, C. D., & Miranda, R. C. (2021). CIRCULATING MICRORNA BIOMARKERS FOR INFANT NEURODEVELOPMENTAL DEFICITS DUE TO PRENATAL ALCOHOL EXPOSURE. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 45, 29A-29A.
  • Raghunathan, R., Liu, C., Singh, M., Miranda, R. C., & Larin, K. V. (2021). A comparison of microvasculature changes in the fetal brain and maternal extremities due to prenatal alcohol exposure using optical coherence angiography. Dynamics and Fluctuations in Biomedical Photonics XVIII, Dynamics and Fluctuations in Biomedical Photonics XVIII. 11641, 1164109-1164109-5.
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  • Mahnke, A. H., Leeman, L., Luo, L., Abdelfattah, A., Shrestha, S., Miranda, R. C., & Bakhireva, L. N. (2019). Neonatal Cord Blood miRNAs As Biomarkers of Neonatal Opioid Withdrawal Syndrome. BIRTH DEFECTS RESEARCH. 111(9), 493-493.
  • Raghunathan, R., Liu, C., Kouka, A., Singh, M., Miranda, R. C., & Larin, K. V. (2019). In utero optical coherence tomography reveals changes in murine embryonic brain vasculature after prenatal cannabinoid exposure. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII. 10867, 108671x.
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Repository Documents / Preprints1
  • Tseng, A. M., Mahnke, A. H., Wells, A. B., Salem, N. A., Allan, A. M., Roberts, V., ... Miranda, R. C. (2018). Maternal Circulating MiRNAs That Predict Infant FASD Outcomes Influence Placental Maturation.
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researcher on
chaired theses and dissertations
Email
rmiranda@tamu.edu
First Name
Rajesh
Last Name
Miranda
mailing address
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS
College Station, TX 77843-1114
USA