overview

My laboratory is interested in developing transgenic animal models of disease and novel platforms for the production of biopharmaceuticals. We are currently exploring methods to produce vaccines in the milk of transgenic animals.

selected publications
Academic Articles95
  • Williams, D. K., Pinzón, C., Huggins, S., Pryor, J. H., Falck, A., Herman, F., ... Gaddy, D. (2018). Genetic engineering a large animal model of human hypophosphatasia in sheep.. SCIENTIFIC REPORTS. 8(1), 16945.
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  • Skiles, W. M., Kester, A., Pryor, J. H., Westhusin, M. E., Golding, M. C., & Long, C. R. (2018). Oxygen-induced alterations in the expression of chromatin modifying enzymes and the transcriptional regulation of imprinted genes. Gene Expr Patterns. 28, 1-11.
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  • Golding, M. C., Snyder, M., Williamson, G. L., Veazey, K. J., Peoples, M., Pryor, J. H., Westhusin, M. E., & Long, C. R. (2015). Histone-lysine N-methyltransferase SETDB1 is required for development of the bovine blastocyst. Theriogenology. 84(8), 1411-1422.
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  • Long, C. R., Westhusin, M. E., & Golding, M. C. (2013). Reshaping the transcriptional frontier: Epigenetics and somatic cell nuclear transfer. Molecular Reproduction and Development. 81(2), 183-193.
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  • Cornetta, K., Tessanne, K., Long, C., Yao, J., Satterfield, C., & Westhusin, M. (2012). Transgenic sheep generated by lentiviral vectors: safety and integration analysis of surrogates and their offspring. Transgenic Research. 22(4), 737-745.
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Conference Papers18
  • Williams, D. K., Pinzon, C. A., Huggins, S., Pryor, J. H., Georges, H. M., Hermann, F., ... Suva, L. J. (2018). Genetically Engineering a Sheep Model of Hypophosphatasia. FASEB J. 32(S1), 859.10-859.10.
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  • Williams, D. K., Pryor, J. H., Huggins, S., Georges, H. M., Pinzon, C. A., Hermann, F., ... Suva, L. J. (2017). Genetic engineering a sheep model of Hypophosphatasia.. JOURNAL OF BONE AND MINERAL RESEARCH. 32, S397-S397.
  • WOLFE, B. A., WESTHUSIN, M. E., STEPP, P., & KRAEMER, D. C. (2016). EMBRYOS PRODUCED BY THE TRANSFER OF CAPRINE NUCLEI TO ENUCLEATED BOVINE OOCYTES ARE CAPABLE OF CLEAVAGE BUT DO NOT DEVELOP TO BLASTOCYSTS. Biology of Reproduction. 50, 72-72.
  • Long, C. R., Golding, M. C., & Westhusin, M. E. (2014). Lentivirus mediated transgenic livestock: applications in biomedical research. Transgenic Research. 23(1), 192-193.
  • Romano, J. E., Thompson, J. A., Kraemer, D. C., Westhusin, M. E., Forrest, D. W., & Tomaszweski, M. A. (2006). Early pregnancy diagnosis by palpation per rectum on embryo/fetus viability in dairy cattle. Theriogenology. 66(3), 667-667.
chaired theses and dissertations
Email
m-westhusin@tamu.edu
First Name
Mark
Last Name
Westhusin
mailing address
Texas A&M University; Vet Med - Physiology & Pharmacology; 4466 TAMU
College Station, TX 77843-4466
USA