overview
My laboratory is interested in developing transgenic animal models of disease and novel platforms for the production of biopharmaceuticals. We are currently exploring methods to produce vaccines in the milk of transgenic animals.
education and training
- Ph.D. in Veterinary Physiology, Texas A&M University - (College Station, Texas, United States) 1986
- M.S. in Veterinary Physiology, Texas A&M University - Corpus Christi - (Corpus Christi, Texas, United States) 1983
- B.S. in Animal Science, Kansas State University - (Manhattan, Kansas, United States) 1980
selected publications
Academic Articles95
- Williams, D. K., Pinzn, C., Huggins, S., Pryor, J. H., Falck, A., Herman, F., ... Gaddy, D. (2018). Genetic engineering a large animal model of human hypophosphatasia in sheep.. Sci Rep. 8(1), 16945.
- Skiles, W. M., Kester, A., Pryor, J. H., Westhusin, M. E., Golding, M. C., & Long, C. R. (2018). Oxygen-induced alterations in the expression of chromatin modifying enzymes and the transcriptional regulation of imprinted genes.. Gene Expr Patterns. 28, 1-11.
- Golding, M. C., & Westhusin, M. E. (2016). Analysis of DNA (cytosine 5) methyltransferase mRNA sequence and expression in bovine preimplantation embryos, fetal and adult tissues.. Gene Expr Patterns. 3(5), 551-558.
- Golding, M. C., Snyder, M., Williamson, G. L., Veazey, K. J., Peoples, M., Pryor, J. H., Westhusin, M. E., & Long, C. R. (2015). Histone-lysine N-methyltransferase SETDB1 is required for development of the bovine blastocyst.. Theriogenology. 84(8), 1411-1422.
- Long, C. R., Westhusin, M. E., & Golding, M. C. (2014). Reshaping the transcriptional frontier: epigenetics and somatic cell nuclear transfer.. Mol Reprod Dev. 81(2), 183-193.
Conference Papers18
- Williams, D. K., Pinzon, C. A., Huggins, S., Pryor, J. H., Georges, H. M., Hermann, F., ... Suva, L. J. (2018). Genetically Engineering a Sheep Model of Hypophosphatasia. FASEB JOURNAL. 32(1), 859.10-859.10.
- Williams, D. K., Pryor, J. H., Huggins, S., Georges, H. M., Pinzon, C. A., Hermann, F., ... Suva, L. J. (2017). Genetic engineering a sheep model of Hypophosphatasia.. JOURNAL OF BONE AND MINERAL RESEARCH. 32, S397-S397.
- Long, C. R., Golding, M. C., & Westhusin, M. E. (2014). Lentivirus mediated transgenic livestock: applications in biomedical research. TRANSGENIC RESEARCH. 23(1), 192-193.
- Romano, J. E., Thompson, J. A., Kraemer, D. C., Westhusin, M. E., Forrest, D. W., & Tomaszweski, M. A. (2006). Early pregnancy diagnosis by palpation per rectum on embryo/fetus viability in dairy cattle. THERIOGENOLOGY. 66(3), 667-667.
- Elhassan, Y. M., Zhang, X., Kramer, D. C., & Westhusin, M. E. (2000). Blastocyst development of in vitro produced morula-stage bovine embryos briefly exposed to Ultraviolet light following Hoechst staining.. BIOLOGY OF REPRODUCTION. 62, 253-253.
in the news
researcher on
Principal Investigator3
Co-Principal Investigator1
recent teaching activities
- BIOT684 Directed Prof Internship Instructor
- BIOT684 Directed Prof Intrn Instructor
- BIOT684 Directed Prof Intrn: In-ab Instructor
- BIOT685 Directed Studies Instructor
- BIOT685 Directed Studies: In-ab Instructor
chaired theses and dissertations
- Campbell, Scott Robert (2016-12). Development and Evaluation of an Oral Contraceptive for Wild Pigs. (Master's Thesis)
- Peoples, Michael D 1978- (2010-12). Identification and Characterization of Bovine Pol III Promoters to Express a Short-Hairpin RNA. (Master's Thesis)
- Tessanne, Kimberly J. (2009-12). Development of Transgenic Livestock with Reduced Myostatin Expression Using RNA Interference. (Doctoral Dissertation)
- Willingham-Rocky, Lauri A. (2008-12). Evaluation of oocyte competency in bovine and canine species via non-invasive assessment of oocyte quality. (Doctoral Dissertation)
- Liu, Jie (2008-05). Recovery and evaluation of somatic cells from ovine and bovine semen for use in nuclear transfer. (Doctoral Dissertation)
Email
m-westhusin@tamu.edu
First Name
Mark
Last Name
Westhusin
mailing address
Texas A&M University; Vet Med - Physiology & Pharmacology; 4466 TAMU
College Station, TX 77843-4466
USA