overview
Mammalian comparative genomics, phylogeny, biogeography, and molecular evolution, with a specific emphasis on feline evolutionary genomics, including: gene mapping, sex chromosome genetics, speciation and mechanisms of male hybrid sterility.
education and training
- Frederick National Laboratory for Cancer Research - (Frederick, Maryland, United States), Postdoctoral Training 2003
- Ph.D. in Biological Sciences, University of Tulsa - (Tulsa, Oklahoma, United States) 1997
- B.S. in Biological Sciences, Illinois State University - (Normal, Illinois, United States) 1992
selected publications
Academic Articles158
- Murphy, W. J., & Harris, A. J. (2024). Toward telomere-to-telomere cat genomes for precision medicine and conservation biology.. Genome Research. 34(5), 655-664.
- Bredemeyer, K. R., vonHoldt, B. M., Foley, N. M., Childers, I., Brzeski, K. E., & Murphy, W. J. (2024). The value of hybrid genomes: Building two highly contiguous reference genome assemblies to advance Canis genomic studies.. Journal of Heredity. esae013.
- Foley, N. M., Harris, A. J., Bredemeyer, K. R., Ruedi, M., Puechmaille, S. J., Teeling, E. C., Criscitiello, M. F., & Murphy, W. J. (2024). Karyotypic stasis and swarming influenced the evolution of viral tolerance in a species-rich bat radiation.. 4(2), 100482-100482.
- Yuan, J., Kitchener, A. C., Lackey, L. B., Sun, T., Jiangzuo, Q., Tuohetahong, Y., ... Li, G. (2024). The genome of the black-footed cat: Revealing a rich natural history and urgent conservation priorities for small felids.. Proceedings of the National Academy of Sciences of the United States of America. 121(2), e2310763120.
- Lescroart, J., Bonilla-Snchez, A., Napolitano, C., Buitrago-Torres, D. L., Ramrez-Chaves, H. E., Pulido-Santacruz, P., ... Eizirik, E. (2023). Extensive Phylogenomic Discordance and the Complex Evolutionary History of the Neotropical Cat Genus Leopardus.. Molecular Biology and Evolution (MBE). 40(12), msad255.
Chapters8
- Murphy, W. J. (2016). Evolution, phylogeny, ecology, and conservation of the clade Glires: Lagomorpha and Rodentia. Wilson, D. E., Lacher, T. E., & Mittermeier, R. A. (Eds.), Handbook of the Mammals of the World. 15-26. Lynx Edicions.
- Eizirik, E., & Murphy, W. J. (2009). Carnivores (Carnivora). Hedges, S. B., & Kumar, S. (Eds.), The Timetree of Life. 504-507. OUP Oxford.
- Murphy, W. J., & Eizirik, E. (2009). Placental Mammals (Eutheria). Hedges, S. B., & Kumar, S. (Eds.), The Timetree of Life. 471-474. OUP Oxford.
- Page, J. E., & Murphy, W. J. (2008). Construction of radiation hybrid panels.. Methods in molecular biology (Clifton, N.J.). Murphy, W. J. (Eds.), Phylogenomics. 51-64. Springer Nature.
- Springer, M. S., Murphy, W. J., Eizirik, E., Madsen, O., Scally, M., Douady, C. J., ... O'Brien, S. J. (2007). A Molecular Classification for the Living Orders of Placental Mammals and the Phylogenetic Placement of Primates. Ravosa, M. J., & Dagosto, M. (Eds.), PRIMATE ORIGINS: Adaptations and Evolution. 1-28. Springer Nature.
Repository Documents / Preprints7
- Mouton, A., Bird, D., Li, G., Craven, B. A., Levine, J. M., Morselli, M., ... Murphy, W. J. (2024). Genetic and anatomical determinants of olfaction in dogs and wild canids.
- Carroll, R. A., Rice, E. S., Murphy, W. J., Lyons, L. A., Coghill, L., Swanson, W. F., ... Warren, W. C. (2022). A novel fishing cat reference genome for the evaluation of potential germline risk variants.
- Foley, N. M., Mason, V. C., Harris, A. J., Bredemeyer, K. R., Damas, J., Lewin, H. A., ... Murphy, W. J. (2022). A genomic timescale for placental mammal evolution.
- vonHoldt, B. M., Brzeski, K. E., Aardema, M. L., Schell, C., Rutledge, L. Y., Fain, S. R., ... Murphy, W. J. (2021). Persistence and expansion of cryptic endangered red wolf genomic ancestry along the American Gulf coast.
- Wang, R. J., Raveendran, M., Harris, R. A., Murphy, W. J., Lyons, L. A., Rogers, J., & Hahn, M. W. (2021). De novo mutations in domestic cat are consistent with an effect of reproductive longevity on both the rate and spectrum of mutations.
editor of
Books1
in the news
researcher on
Principal Investigator3
awards and honors
recent teaching activities
- BICH491 Hnr-research Instructor
- BICH491 Research Instructor
- BIMS320 Biomedical Genetics Instructor
- BIMS320 Biomedical Genetics-costa Rica Instructor
- BIMS320 Biomedical Genetics: Cri Instructor
chaired theses and dissertations
- Davis, Brian W (2013-05). Genomics and Transcriptomics of Hybrid Male Sterility Assessed in Multiple Interspecies Feline Breeds. (Doctoral Dissertation)
- Davis, Brian W. (2010-10). Resolution of Phylogenetic Relationships and Characterization of Y-Linked Microsatellites within the Big Cats, Panthera. (Master's Thesis)
Email
wmurphy@tamu.edu
First Name
William
Last Name
Murphy
mailing address
Texas A&M University; Veterinary Integrative Biosciences; 4458 TAMU
College Station, TX 77843-4458
USA