overview

Mammalian comparative genomics, phylogeny, biogeography, and molecular evolution, with a specific emphasis on feline evolutionary genomics, including: gene mapping, sex chromosome genetics, speciation and mechanisms of male hybrid sterility.

education and training
selected publications
Academic Articles134
  • Myers, A. N., Lawhon, S. D., Diesel, A. B., Bradley, C. W., Rodrigues Hoffmann, A., Murphy, W. J., & 99 Lives Cat Genome Consortium. (2022). An ancient haplotype containing antimicrobial peptide gene variants is associated with severe fungal skin disease in Persian cats.. PLoS Genet. 18(2), e1010062-e1010062.
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  • Wang, R. J., Raveendran, M., Harris, R. A., Murphy, W. J., Lyons, L. A., Rogers, J., & Hahn, M. W. (2022). De novo Mutations in Domestic Cat are Consistent with an Effect of Reproductive Longevity on Both the Rate and Spectrum of Mutations.. Mol Biol Evol. 39(7), msac147.
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  • vonHoldt, B. M., Brzeski, K. E., Aardema, M. L., Schell, C. J., Rutledge, L. Y., Fain, S. R., ... Murphy, W. J. (2022). Persistence and expansion of cryptic endangered red wolf genomic ancestry along the American Gulf coast.. Mol Ecol. 31(21), 5440-5454.
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  • Harris, A. J., Foley, N. M., Williams, T. L., & Murphy, W. J. (2022). Tree House Explorer: A Novel Genome Browser for Phylogenomics.. Mol Biol Evol. 39(6), msac130.
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  • Lorenzana, G. P., Figueir, H. V., Kaelin, C. B., Barsh, G. S., Johnson, J., Karlsson, E., ... Eizirik, E. (2022). Whole-genome sequences shed light on the demographic history and contemporary genetic erosion of free-ranging jaguar (Panthera onca) populations.. J Genet Genomics. (1), 77-80.
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Chapters8
  • Murphy, W. J. (2016). Evolution, phylogeny, ecology, and conservation of the clade Glires: Lagomorpha and Rodentia. Wilson, D. E., Lacher, T. E., & Mittermeier, R. A. (Eds.), Handbook of the Mammals of the World. 15-26. Lynx Edicions.
  • Eizirik, E., & Murphy, W. J. (2009). Carnivores (Carnivora). Hedges, S. B., & Kumar, S. (Eds.), The Timetree of Life. 504-507. OUP Oxford.
  • Murphy, W. J., & Eizirik, E. (2009). Placental Mammals (Eutheria). Hedges, S. B., & Kumar, S. (Eds.), The Timetree of Life. 471-474. OUP Oxford.
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  • Page, J. E., & Murphy, W. J. (2008). Construction of radiation hybrid panels.. Methods in Molecular Biology. Murphy, W. J. (Eds.), Phylogenomics. 51-64. Springer Nature.
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  • Springer, M. S., Murphy, W. J., Eizirik, E., Madsen, O., Scally, M., Douady, C. J., ... O'Brien, S. J. (2007). A Molecular Classification for the Living Orders of Placental Mammals and the Phylogenetic Placement of Primates. Ravosa, M. J., & Dagosto, M. (Eds.), PRIMATE ORIGINS: Adaptations and Evolution. 1-28. Springer Nature.
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Repository Documents / Preprints8
  • Foley, N. M., Mason, V. C., Harris, A. J., Bredemeyer, K. R., Damas, J., Lewin, H. A., ... Murphy, W. J. (2022). A genomic timescale for placental mammal evolution.
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  • Harris, A. J., Foley, N. M., Williams, T. L., & Murphy, W. J. (2022). Tree House Explorer: A Novel Genome Browser for Phylogenomics.
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  • Wang, R. J., Raveendran, M., Harris, R. A., Murphy, W. J., Lyons, L. A., Rogers, J., & Hahn, M. W. (2021). De novo mutations in domestic cat are consistent with an effect of reproductive longevity on both the rate and spectrum of mutations.
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  • Dindot, S. V., Christian, S., Murphy, W. J., Berent, A., Panagoulias, J., Schlafer, A., ... Douville, J. (2021). Development of an ASO therapy for Angelman syndrome by targeting an evolutionarily conserved region at the start of the UBE3A-AS transcript.
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  • vonHoldt, B. M., Brzeski, K. E., Aardema, M. L., Schell, C., Rutledge, L. Y., Fain, S. R., ... Murphy, W. J. (2021). Persistence and expansion of cryptic endangered red wolf genomic ancestry along the American Gulf coast.
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editor of
Books1
in the news
chaired theses and dissertations
Email
wmurphy@tamu.edu
First Name
William
Last Name
Murphy
mailing address
Texas A&M University; Veterinary Integrative Biosciences; 4458 TAMU
College Station, TX 77843-4458
USA