Pietrantonio, Patricia individual record
Professor and Texas AgriLife Research Fellow

We work with important pests that are critical to Texas and the world focusing on public and animal health and on pests of cotton. We are interested in elucidating the functions of arthropod neuropeptides that signal through G protein-coupled receptors. Many of these neuropeptides are pleiotropic and many of their multiple functions are still unknown. We utilize loss-of-function experiments through RNAi, peptidomimetics, the discovery of antagonists through target-based high-throughput screening of small molecules on recombinant receptors expressed in mammalian cells, immunohistochemistry, and develop physiological in vitro and in vivo assays towards advancing arthropod endocrinology. The laboratory has pioneered the discovery of the first neuropeptide receptor in the Acari and the first insect prostaglandin receptor. The molecular and cell culture laboratories are BL2 and the Insect toxicology laboratory is BL1. We use state-of-the-art technologies and the lab is well equipped to do almost everything in-house.

selected publications
Academic Articles60
  • Xiong, C., Yang, Y., Nachman, R. J., & Pietrantonio, P. V. (2021). Tick CAPA propeptide cDNAs and receptor activity of endogenous tick pyrokinins and analogs: Towards discovering pyrokinin function in ticks. Peptides. 146, 170665-170665.
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  • Hernandez, J. R., Longnecker, M., Fredregill, C. L., Debboun, M., & Pietrantonio, P. V. (2021). Kdr genotyping (V1016I, F1534C) of the Nav channel of Aedes aegypti (L.) mosquito populations in Harris County (Houston), Texas, USA, after Permanone 31–66 field tests and its influence on probability of survival. PLOS Neglected Tropical Diseases. 15(11), e0009833-e0009833.
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  • Lee, H., Longnecker, M., Calkins, T. L., Renfro, A. D., Fredregill, C. L., Debboun, M., & Pietrantonio, P. V. (2020). Detection of the Nav channel kdr-like mutation and modeling of factors affecting survivorship of Culex quinquefasciatus mosquitoes from six areas of Harris County (Houston), Texas, after permethrin field-cage tests.. PLoS Negl Trop Dis. 14(11), e0008860-e0008860.
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  • Xiong, C., Kaczmarek, K., Zabrocki, J., Nachman, R. J., & Pietrantonio, P. V. (2020). Activity of native tick kinins and peptidomimetics on the cognate target G protein‐coupled receptor from the cattle fever tick, Rhipicephalus microplus (Acari: Ixodidae). Pest Manag Sci. 76(10), 3423-3431.
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  • Nachman, R. J., & Pietrantonio, P. V. (2010). Interaction of mimetic analogs of insect kinin neuropeptides with arthropod receptors.. MATHEMATICAL MODELLING IN EXPERIMENTAL NUTRITION. Neuropeptide Systems as Targets for Parasite and Pest Control. 27-48. Springer US.
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  • Pietrantonio, P. (2005). Driving forces for target-based insecticide design in the twenty-first century. Entomology at the Land Grant University: Perspectives from the Texas A&M University Department Centenary. 328-338.
  • Pietrantonio, P. V., & Gill, S. S. (1996). Bacillus thuringiensis endotoxins: action on the insect midgut. Biology of the Insect Midgut. 345-372. Springer Netherlands.
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Conference Papers12
  • Pietrantonio, P. (2016). Neuropeptide signaling in the red imported fire ant in nutrition, reproduction, and division of labor. 2016 International Congress of Entomology, 2016 International Congress of Entomology.
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  • Kaczmarek, K. K., Pietrantonio, P., Coast, G., Zabrocki, J., & Nachman, R. (2010). A non-peptide mimetic insect kinin agonist interacts with an expressed receptor and an in vitro diuretic assay in the mosquito Aedes aegypti. JOURNAL OF PEPTIDE SCIENCE. 16, 154-154.
  • Nachman, R. J., Pietrantonio, P. V., & Coast, G. M. (2009). Toward the development of novel pest management agents based upon insect kinin neuropeptide analogues.. Ann N Y Acad Sci. 1163(1), 251-261.
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  • Junck, T., Bogran, C. E., & Pietrantonio, P. (2008). Monitoring Bemisia resistance to neonicotinoid insecticides in floriculture crops. JOURNAL OF INSECT SCIENCE. 8, 25-25.
recent teaching activities
chaired theses and dissertations
First Name
Last Name
mailing address
Texas A&M University; Entomology; 2475 TAMU
College Station, TX 77843-2475