Cho, Jae individual record
Assistant Professor
overview

Our research interests lie in the interface between biology and other areas of science (chemistry and physics). NMR is our primary tool for structural and biophysical analysis. We also extensively use other techniques including Circular Dichroism and Fluorescence spectroscopy, and Isothermal calorimetry. These biophysical analyses are corroborated by sophisticated engineering and tuning of target proteins using semi-synthetic chemical biology techniques, in addition to traditional molecular biology methods.

selected publications
Academic Articles29
  • Shi, J., Shen, Q., Cho, J., & Hwang, W. (2020). Entropy Hotspots for the Binding of Intrinsically Disordered Ligands to a Receptor Domain.. Biophys J. 118(10), 2502-2512.
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  • Shen, Q., Bhatt, V. S., Krieger, I., Sacchettini, J. C., & Cho, J. (2018). Structure-guided design of a potent peptide inhibitor targeting the interaction between CRK and ABL kinase.. Medchemcomm. 9(3), 519-524.
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  • Shen, Q., Zeng, D., Zhao, B., Bhatt, V. S., Li, P., & Cho, J. (2017). The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.. ACS Chem Biol. 12(5), 1199-1203.
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  • Sato, S., Cho, J., Peran, I., Soydaner-Azeloglu, R. G., & Raleigh, D. P. (2017). The N-Terminal Domain of Ribosomal Protein L9 Folds via a Diffuse and Delocalized Transition State.. Biophys J. (9),
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Email
jaehyuncho@tamu.edu
First Name
Jae
Last Name
Cho
mailing address
Texas A&M University; Biochemistry & Biophysics; 2128 TAMU
College Station, TX 77843-2128
USA