Scholars

Rajendran, Praveen

Associate Professor

Positions:

Associate Professor, Institute of Biosciences and Technology, School of Medicine

Research Areas:

Cancer--Research

Single Page Bio

Profile Summary

prajendran@tamu.edu

1 713 677 7522

Co-author Network

Map of Science

Co-investigator Network

ORCID

0000-0002-6221-7366

Research Areas:

Cancer--Research

overview

My research focuses on the discovery and development of novel therapies for colorectal cancer interception and investigating epigenetic pathways implicated in the early stages of the disease. As PI or co-Investigator on several NIH-funded grants, I laid the groundwork in identifying novel epigenetic mechanisms of dietary compounds that affect Wnt/?-catenin and DNA repair.

I also have extensive Pharma R&D expertise in developing novel anticancer drugs through close collaboration with R&D teams. As the Director of Antibody and Biopharmaceuticals Core (ABC), I support and advance the development of monoclonal antibodies.

education and training

Ph.D. in Pharmacology, Birla Institute of Technology and Science, Pilani - Goa Campus - (Sancoale, India) 2007

selected publications

Academic Articles41

Zhang, S., Kapoor, S., Tripathi, C., Perez, J. T., Mohan, N., Dashwood, W. M., ... Dashwood, R. (2023). Targeting ACE2-BRD4 crosstalk in colorectal cancer and the deregulation of DNA repair and apoptosis.. NPJ Precis Oncol. 7(1), 20.
Chen, Y., Li, J., Neja, S., Menon, R., Jayaraman, A., Lee, K., ... Dashwood, R. (2022). Abstract A013: Metabolomics of acute vs. chronic spinach intake in an Apc-mutant genetic background: linoleate and butanoate metabolites targeting HDAC activity and IFN- signaling. Cancer Prevention Research. 15(12_Supplement_2), a013-a013.
Kapoor, S., Damiani, E., Wang, S., Dharmanand, R., Tripathi, C., Tovar Perez, J. E., ... Dashwood, R. H. (2022). BRD9 Inhibition by Natural Polyphenols Targets DNA Damage/Repair and Apoptosis in Human Colon Cancer Cells.. Nutrients. 14(20), 4317-4317.
Chen, Y., Li, J., Neja, S., Kapoor, S., Tovar Perez, J. E., Tripathi, C., ... Dashwood, R. (2022). Metabolomics of Acute vs. Chronic Spinach Intake in an Apc-Mutant Genetic Background: Linoleate and Butanoate Metabolites Targeting HDAC Activity and IFN- Signaling.. Cells. 11(3), 573-573.
Demirhan, Y. E., Rajendran, P., Dashwood, W., Kapoor, S., Ulusan, A., Tripathi, C., ... Dashwood, R. (2021). S318 Optimized Lower Dose Combinations of Sulindac Plus Erlotinib Sustained Antitumor Efficacy and Reduced Toxicity in a Preclinical Model of FAP. The American Journal of Gastroenterology. 116(1), s138-s138.

Conference Papers13

Chen, Y., Li, J., Neja, S., Menon, R., Jayaraman, A., Lee, K., ... Dashwood, R. (2022). Metabolomics of acute vs. chronic spinach intake in an Apc-mutant genetic background: linoleate and butanoate metabolites targeting HDAC activity and IFN-gamma signaling. CANCER PREVENTION RESEARCH. 15(12),
Chen, Y., Li, J., Neja, S., Menon, R., Jayaraman, A., Lee, K., ... Dashwood, R. (2022). Metabolomics of acute vs. chronic spinach intake in an Apc-mutant genetic background: linoleate and butanoate metabolites targeting HDAC activity and IFN-gamma signaling.. CANCER PREVENTION RESEARCH. 15(12),
Kapoor, S., Gustafson, T., Zhang, M., Chen, Y., Li, J., Nhung, N., ... Dashwood, R. (2021). Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells.. CANCER RESEARCH. 81(13),
Demirhan, Y. E., Rajendran, P., Dashwood, W., Kapoor, S., Ulusan, A., Tripathi, C., ... Dashwood, R. (2021). Optimized Lower Dose Combinations of Sulindac Plus Erlotinib Sustained Antitumor Efficacy and Reduced Toxicity in a Preclinical Model of FAP. AMERICAN JOURNAL OF GASTROENTEROLOGY. 116, S138-S138.
Rajendran, P., Damiani, E., Wang, S., Dashwood, W., & Dashwood, R. H. (2020). Dietary polyphenols as epigenetic 'reader' inhibitors. CANCER RESEARCH. 80(16), 3477-3477.

patents

Patents10

RAJAGOPAL SRIRAM, .., PRAVEEN RAJENDRAN, .., RAJAGOPAL SRIDHARAN, .., KACHHADIA VIRENDRA, .., PONPANDIA THANASEKARAN, .., KEERI ABDUL RAHEEM, .., ANANDHAN KARNAMBARAM, .., & DAIVASIGAMANI PRABHU. (2010). HISTONE DEACETYLASE INHIBITORS.
RAJAGOPAL SRIDHARAN, .., SELVAKUMAR THANGAPAZHAM, .., BHARATHIMOHAN KUPPUSAMY, .., KACHHADIA VIRENDRA, .., RAJAGOPAL SRIRAM, .., PRAVEEN RAJENDRAN, .., & BALAJI RAMACHANDRAN. (2008). STILBENE DERIVATIVES AS PSTAT3/IL-6 INHIBITORS.
RAJAGOPAL SRIDHARAN, .., SELVAKUMAR THANGAPAZHAM, .., BHARATHIMOHAN KUPPUSAMY, .., KACHHADIA VIRENDRA, .., RAJAGOPAL SRIRAM, .., PRAVEEN RAJENDRAN, .., & BALAJI RAMACHANDRAN. (2008). STILBENE DERIVATIVES AS PSTAT3/IL-6 INHIBITORS.
RAJAGOPAL SRIDHARAN, .., KACHHADIA VIRENDRA, .., PONPANDIAN THANASEKARAN, .., KEERI ABDUL RAHEEM, .., ANANDHAN KARNAMBARAM, .., RAJAGOPAL SRIRAM, .., PRAVEEN RAJENDRAN, .., & DAIVASIGAMANI PRABHU. (2008). HISTONE DEACETYLASE INHIBITORS.
RAJAGOPAL SRIDHARAN, .., KACHHADIA VIRENDRA, .., PONPANDIAN THANASEKARAN, .., KEERI ABDUL RAHEEM, .., ANANDHAN KARNAMBARAM, .., RAJAGOPAL SRIRAM, .., PRAVEEN RAJENDRAN, .., & DAIVASIGAMANI PRABHU. (2008). HISTONE DEACETYLASE INHIBITORS.