Scholars

Rusyn, Ivan

Professor

Positions:

Faculty Fellow, Center for Health Systems and Design, College of Architecture
Professor, Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences

Research Areas:

Risk assessment, Toxicology

UN Sustainable Development Goals:

Single Page Bio

Profile Summary

irusyn@tamu.edu

1 979 458 9866

Co-author Network

Map of Science

Co-investigator Network

ORCID

0000-0001-9340-7384

UN Sustainable Development Goals:

Research Areas:

Risk assessment, Toxicology

overview

My laboratory has an active research portfolio funded by the National Institutes of Health and the US EPA with a focus on the mechanisms of action of environmental toxicants and the genetic determinants of the susceptibility to toxicant-induced injury. Through a combination of in vivo animal studies and experiments that utilize cellular and molecular models, we aim to better understand why certain chemicals cause cancer or organ damage in rodents and whether humans in general, or any susceptible sub-population in particular, are at risk from similar exposures.

The main focus of our inter-disciplinary research is on improving the linkages between exposures and adverse health effects Specifically, we develop innovative experimental methods and computational tools which enable analysis of data across multiple dimensions including SNPs, -omic endpoints, multiple chemicals and traditional toxicity phenotypes.

education and training

Ph.D. in Toxicology, University of North Carolina at Chapel Hill - (Chapel Hill, North Carolina, United States) 2000
M.D. in Medicine, Bogomolets National Medical University - (Kiev, Ukraine) 1994

selected publications

Academic Articles217

Erber, L., Goodman, S., Wright, F. A., Chiu, W. A., Tretyakova, N. Y., & Rusyn, I. (2021). Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following Inhalation Exposure to 1,3-Butadiene. Chemical Research in Toxicology. 34(11), 2375-2383.
Burnett, S. D., Blanchette, A. D., Chiu, W. A., & Rusyn, I. (2021). Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors. Chemical Research in Toxicology. 34(9), 2110-2124.
Burns, S. J. (2021). Linear dielectric thermodynamics: A new universal law for optical, dielectric constants. Journal of the American Ceramic Society. 104(5), 2087-2101.
Roman-Hubers, A. T., McDonald, T. J., Baker, E. S., Chiu, W. A., & Rusyn, I. (2021). A Comparative Analysis of Analytical Techniques for Rapid Oil Spill Identification.. Environ Toxicol Chem. 40(4), 1034-1049.
Aly, N. A., Casillas, G., Luo, Y., McDonald, T. J., Wade, T. L., Zhu, R., ... Rusyn, I. (2021). Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks.. J Expo Sci Environ Epidemiol. 31(5), 810-822.

Books2

Pogribny, I. P., & Rusyn, I. (2013). Environmental toxicants, epigenetics, and cancer.. Springer Nature.
Allen, N., Anderson, L. M., Beland, F. A., Bnichou, J., Beral, V., Bloomfield, K., ... Russell, D. (2010). Alcohol consumption and ethyl carbamate.

Chapters2

Onel, M., Beykal, B., Wang, M., Grimm, F. A., Zhou, L., Wright, F. A., ... Pistikopoulos, E. N. (2018). Optimal Chemical Grouping and Sorbent Material Design by Data Analysis, Modeling and Dimensionality Reduction Techniques.. 20TH EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING. Computer Aided Chemical Engineering. 421-426. Elsevier.
Starlard-Davenport, A., Tryndyak, V., Kosyk, O., Ross, S. R., Rusyn, I., Beland, F. A., & Pogribny, I. P. (2010). Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis.. RETURN OF OMEGA-3 FATTY ACIDS INTO THE FOOD SUPPLY. World Review of Nutrition and Dietetics. 123-130. KARGER.