Rimer, Mendell individual record
Associate Professor

Research in our lab centers on the molecular and cellular mechanisms underlying the formation, maintenance and pathology of synapses, the connections between nerve cells and their targets. Because of its simplicity and experimental accessibility we have used the vertebrate neuromuscular junction (NMJ) as our model system. The NMJ is the synapse between a motor neuron and a skeletal muscle fiber. We address these problems using state-of-the-art mouse molecular genetic techniques in combination with standard molecular, cellular, and immunological approaches.

selected publications
Academic Articles30
  • Lee, Y. I., & Rimer, M (2020). Wesley J. Thompson (1947-2019).. Front Mol Neurosci. 13, 91.
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  • Rimer, M., Seaberg, B. L., Yen, P., Lam, S., Hastings, R. L., Lee, Y. I., ... Ko, C (2019). Nerve sprouting capacity in a pharmacologically induced mouse model of spinal muscular atrophy.. Sci Rep. 9(1), 7799.
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  • Seaberg, B., Henslee, G., Wang, S., Paez-Colasante, X., Landreth, G. E., & Rimer, M (2015). Muscle-derived extracellular signal-regulated kinases 1 and 2 are required for the maintenance of adult myofibers and their neuromuscular junctions.. Mol Cell Biol. 35(7), 1238-1253.
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chaired theses and dissertations
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mailing address
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS
College Station, TX 77843-1114