Rimer, Mendell
individual record
Associate Professor
Positions:
- Associate Professor, Neuroscience and Experimental Therapeutics, College of Medicine
overview
Research in our lab centers on the molecular and cellular mechanisms underlying the formation, maintenance and pathology of synapses, the connections between nerve cells and their targets. Because of its simplicity and experimental accessibility we have used the vertebrate neuromuscular junction (NMJ) as our model system. The NMJ is the synapse between a motor neuron and a skeletal muscle fiber. We address these problems using state-of-the-art mouse molecular genetic techniques in combination with standard molecular, cellular, and immunological approaches.
education and training
- New York University - (New York, New York, United States), Postdoctoral Training 2000
- New Mexico State University - (Las Cruces, New Mexico, United States), Postdoctoral Training 1998
- Stanford University - (Stanford, California, United States), Postdoctoral Training 1997
- Ph.D. in Molecular and Cell Biology, University of Maryland, Baltimore - (Baltimore, Maryland, United States) 1993
- B.S. in Biology, University of the Andes - (Mérida, Venezuela) 1986
selected publications
Academic Articles22
- Rimer, M. (2020). Extracellular signal-regulated kinases 1 and 2 regulate neuromuscular junction and myofiber phenotypes in mammalian skeletal muscle. Neurosci Lett. 715, 134671-134671.
- Lee, Y. I., & Rimer, M. (2020). Wesley J. Thompson (1947–2019). FRONTIERS IN MOLECULAR NEUROSCIENCE. 13, 91.
- Rimer, M., Seaberg, B. L., Yen, P., Lam, S., Hastings, R. L., Lee, Y. I., ... Ko, C. (2019). Nerve sprouting capacity in a pharmacologically induced mouse model of spinal muscular atrophy. SCIENTIFIC REPORTS. 9(1), 7799.
- Wang, S., Seaberg, B., Paez-Colasante, X., & Rimer, M. (2017). Erratum: Corrigendum: Defective Acetylcholine Receptor Subunit Switch Precedes Atrophy of Slow-Twitch Skeletal Muscle Fibers Lacking ERK1/2 Kinases in Soleus Muscle. SCIENTIFIC REPORTS. 7(1), 45420.
- Seaberg, B., Henslee, G., Wang, S., Paez-Colasante, X., Landreth, G. E., & Rimer, M. (2015). Muscle-Derived Extracellular Signal-Regulated Kinases 1 and 2 Are Required for the Maintenance of Adult Myofibers and Their Neuromuscular Junctions. Mol Cell Biol. 35(7), 1238-1253.
teaching activities
- MSCI691 Research Credit: Medical Sci Instructor
- NRSC485 Directed Studies Instructor
- NRSC485 Hnr-directed Studies Instructor
- NRSC491 Hnr-research Instructor
- NRSC491 Research Instructor
chaired theses and dissertations
- Paez, Ximena (2014-08). Motor Neuron-Specific Restoration of SMN in Two SMA Mouse Models: Insights into the Role of Motor Neurons in Spinal Muscular Atrophy. (Doctoral Dissertation)
Email
rimer@tamu.edu
First Name
Mendell
Last Name
Rimer
mailing address
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS
College Station, TX 77843-1114
USA