Probing the metal specificity mechanism of superoxide dismutase from human pathogen Clostridium difficile | Academic Article individual record
abstract

The molecular mechanism of the metal specificity to superoxide dismutase from human pathogen C. difficile (SODcd) was investigated by X-ray crystallography, spectroscopy, SOD activity assay, electrochemistry, and DFT calculations, and the results indicate that the cognate metal characters tuned by the metal micro-environment dominate the metal specificity of the SODcd.

authors
author list (cited authors)
Li, W., Wang, H., Chen, Z., Ye, Q., Tian, Y., Xu, X., ... Tan, X.
publication date
2014
published in
keywords
  • Clostridium Difficile
  • Superoxide Dismutase
  • Electron Spin Resonance Spectroscopy
  • Metals
  • Protein Structure, Tertiary
  • Humans
altmetric score

0.5

citation count

4