An expression system for Gustatory receptors—And why it failed | Academic Article individual record
abstract

A recent paper by the Dahankuar laboratory suggested that single Drosophila sugar receptors proteins accurately mediate sugar detection when ectopically expressed in olfactory neurons of the antenna. These findings contra-dict numerous previously published electrophysiological and behavioral investigations, which all point towards heteromultimeric sugar taste receptors. Here, I provide some explanation why this “pseudo-heterologous” expression system may have led to this misleading conclusion. © 2014 Taylor & Francis Group, LLC.

author list (cited authors)
Amrein, H.
publication date
2015
keywords
  • Taste Buds
  • Heterodimers
  • Gr Genes
  • Receptors, Cell Surface
  • Olfactony Learning And Memory
  • Taste Receptors
  • Olfactory Neuron
  • Taste
  • Drosophila
  • Animals
  • Expression System
citation count

2