His research interests are in solving grand challenge problems in the broad areas of health and energy through the use of micro/nano systems technologies. His work in these areas has focused on the development of in vivo like in vitro systems through microfluidic lab-on-a-chip technologies (e.g., organ-on-a-chip & microphysiological systems, developmental neurobiology models of the central nervous system, blood-brain-barrier-on-a-chip, gastrointestinal tract-on-a-chip, high throughput live cell arrays), development of high throughput single-cell physio-chemical analysis platforms, and development of microbial systems as biorefineries for bioelectricity and biofuel production while simultaneously utilizing wastewater.
He has co-authored more than 80 peer-reviewed publications and has received funding from the Bill and Melinda Gates Foundation, National Institutes of Health (NIH), National Science Foundation (NSF), Defense Threat Reduction Agency (DTRA), United States Department of Agriculture (USDA), U.S. Army Corp of Engineers, Qatar National Research Foundation (QNRF), and several other international sponsors and private companies. He currently serves as the editorial board member of the journal PLoS ONE and as an associate editor for the journal Biomedical Microdevices.
- Ph.D. in , Georgia Institute of Technology - (Atlanta, Georgia, United States) 2005
- M.S. in , University of Cincinnati - (Cincinnati, Ohio, United States) 2000
- B.S. in , Seoul National University - (Seoul, South Korea) 1997
- Zhang, H., Anoop, K., Huang, C., Sadr, R., Gupte, R., Dai, J., & Han, A. (2022). A circular gradient-width crossflow microfluidic platform for high-efficiency blood plasma separation. Sensors and Actuators B: Chemical. 354, 131180-131180.
- Grattoni, A., & Han, A. (2022). Biomedical microdevices: the next phase of highlighting scientific discoveries in the field of micro-nanotechnologies for medicine. Biomedical Microdevices. 24(1), 1.
- Kim, S., Richardson, L., Radnaa, E., Chen, Z., Rusyn, I., Menon, R., & Han, A. (2022). Molecular mechanisms of environmental toxin cadmium at the feto-maternal interface investigated using an organ-on-chip (FMi-OOC) model. Journal of Hazardous Materials. 422, 126759-126759.
- Rogers, R. E., Haskell, A., White, B. P., Dalal, S., Lopez, M., Tahan, D., ... Kaunas, R. (2021). A Scalable System for Generation of Mesenchymal Stem Cells Derived from Induced Pluripotent Cells Employing Bioreactors and Degradable Microcarriers. Stem Cells Translational Medicine. 10(12), 1650-1665.
- Radnaa, E., Urrabaz-Garza, R., Elrod, N. D., de Castro Silva, M., Pyles, R., Han, A., & Menon, R. (2021). Generation and characterization of human Fetal membrane and Decidual cell lines for reproductive biology experiments. Biology of Reproduction.
- Purnima Kotu, S., Han, S., Han, A., Mannan, S., & Jayaraman, A. (2019). Lab-on-a-Chip Model for Investigating the Effect of Biocides on Co-Culture Biofilms. Oilfield Microbiology. 129-142. CRC Press.
- Park, J., Kim, S., Li, J., & Han, A. (2015). Multi-compartment NeuronGlia Coculture Microsystem. Neuromethods. Biffi, E. (Eds.), Neuromethods. 149-159. Springer New York.
- Park, J., Kim, S., Li, J., & Han, A. (2014). Axon length quantification microfluidic culture platform for growth and regeneration study.. Methods Mol Biol. Murray, A. J. (Eds.), Methods in Molecular Biology. 85-95. Springer New York.
- Hou, H., Li, L., Cho, Y., de Figueiredo, P., & Han, A. (2011). Microfabricated Microbial Fuel Cell Arrays. Recent Advances in Microbiology. 1-12. Apple Academic Press.
- Londe, G., Han, A., & Cho, H. J. (2008). MEMS for Nanotechnology: Top-down Perspective. Seal, S. (Eds.), Functional Nanostructures. 107-167. Springer New York.
- Tantengco, O., Richardson, L., Radnaa, E., Kammala, A. K., Kechichian, T., Ganguly, E., ... Menon, R. (2022). Cervix-on-a-chip for investigating ascending Ureaplasma parvum infection in pregnancy. American Journal of Obstetrics and Gynecology. 226(1), S12-S13.
- Richardson, L., Kammala, A. K., Kim, S., Han, A., & Menon, R. (2022). Novel Bench-To-Bedside Tools: Feto-Maternal Interface Organ-On-Chip’s. American Journal of Obstetrics and Gynecology. 226(1), S712-S712.
- Kammala, A. K., Richardson, L., Kim, S., Costantine, M. M., Taylor, R., Han, A., & Menon, R. (2022). Testing Pharmacokinetics and Efficacy of Pravastatin Using Feto-Maternal Interface Organ-On-Chips. American Journal of Obstetrics and Gynecology. 226(1), S496-S496.
- Kim, S., Richardson, L., Radnaa, E., Chen, Z., Rusyn, I., Menon, R., & Han, A. (2021). Determining the Impact of Environmental Toxin Cadmium at the Feto-Maternal Interface Using an Organ-on-Chip (FMi-OOC) Device.. REPRODUCTIVE SCIENCES. 28(SUPPL 1), 111A-111A.
- Tantengco, O., Richardson, L., Medina, P. M., Han, A., & Menon, R. (2021). Cervical epithelial organ-on-chip: a platform to study cellular remodeling of the cervix. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 224(2), S408-S408.
- Microfluidic System With Cell-Separating Powers May Unravel How Novel Pathogens Attack Texas A&M Today November 30, 2020
- NIH awards $35.5 million to use bioengineered organ models to improve clinical trials EurekAlert! September 30, 2020
- Texas A&M researchers developing device to identify antibodies to fight COVID-19 Homeland Preparedness News June 4, 2020
- Han, A., & Han, S. (2021). Dielectrophoretic in-droplet material concentrator.
- Han, A., & Kim, H. S. (2017). High-throughput mutagenized cell screening system for selective single cell extraction.
- Sobahi, Nebras Mohammedkamal A (2017-12). DEVELOPMENT OF HIGH-THROUGHPUT IMPEDANCE SPECTROSCOPY-BASED MICROFLUIDIC PLATFORM FOR DETECTING AND ANALYZING CELLS AND PARTICLES. (Doctoral Dissertation)
- Buonocore, John Edward (2017-05). Microfluidics Based Neuronal Aggregate Culturing Device for High Throughput Drug Screening. (Master's Thesis)
- Erbay, Celal (2016-08). Micro/Nano Technologies for Achieving Sustainable Microbial Electrochemical Cell Systems. (Doctoral Dissertation)
- Wang, Han (2015-08). Development of Acoustic Microfluidic Platforms for Separation and Analysis of Particles and Cells. (Doctoral Dissertation)
- Krenek, Keith (2015-05). Microfluidic Acoustic System to Generate Aged Yeast for Cell Aging Studies. (Master's Thesis)