To the Editor: Despite evidence demonstrating the effectiveness of donor-screening procedures for HIV type 1 (HIV-1),1,2there remains considerable concern among members of the general public about the safety of the blood supply. Both indirect and direct estimates of the risk of transfusion-transmitted HIV-1 infection have been reported. Cumming et al.1based their estimate of a risk of 0.00065 percent (1 in 153,000) on test results from donors at 41 regional blood centers in the United States and on the probability of a seropositive donation during an eight-week “window period.” We recently reported the interim results of a large, prospective. © 1990, Massachusetts Medical Society. All rights reserved.
- Blood TransfusionAIDS SerodiagnosisBlood DonorsHIV InfectionsHumansMaleMiddle AgedTransfusion Reaction