Our lab aims to employ design-based engineering to address the challenges in energy, environment, and health. The design-based engineering strategies focused on chemical, computational, and systems biology analyses to understand the fundamental mechanisms and to guide the design of enzymes, processes, microorganisms, and plant for various applications. While the principle can be broadly applied, our research primarily focused on increasing biorefinery waste utilization, enhancing photosynthetic terpene production, and improving enzymes based on structure dynamics.

education and training
selected publications
Academic Articles87
  • Wang, B. o., Xu, Y., Wang, X., Yuan, J. S., Johnson, C. H., Young, J. D., & Yu, J. (2021). A guanidine-degrading enzyme controls genomic stability of ethylene-producing cyanobacteria. Nature Communications. 12(1), 5150.
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  • Hu, C., Zhao, M., Li, Q., Liu, Z., Hao, N., Meng, X., ... Yuan, J. S. (2021). Cover Feature: Phototunable Lignin Plastics to Enable Recyclability (ChemSusChem 19/2021). ChemSusChem. 14(19), 3980-3980.
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  • Arreola-Vargas, J., Meng, X., Wang, Y., Ragauskas, A. J., & Yuan, J. S. (2021). Enhanced medium chain length-polyhydroxyalkanoate production by co-fermentation of lignin and holocellulose hydrolysates. Green Chemistry. 23(20), 8226-8237.
  • Liu, Z., Hao, N., Wang, Y., Dou, C., Lin, F., Shen, R., ... Yuan, J. S. (2021). Transforming biorefinery designs with 'Plug-In Processes of Lignin' to enable economic waste valorization.. Nat Commun. 12(1), 3912.
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  • Li, Q., Hu, C., Li, M., Truong, P., Li, J., Lin, H., ... Yuan, J. S. (2021). Enhancing the multi-functional properties of renewable lignin carbon fibers via defining the structure–property relationship using different biomass feedstocks. Green Chemistry. 23(10), 3725-3739.
  • Liu, Z., & Yuan, J. S. (2018). Chapter 12. Systems Biology Analyses of Lignin Conversion. RSC Energy and Environment Series. Energy and Environment Series. 314-332. Royal Society of Chemistry.
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  • Holopainen, J. K., Himanen, S. J., Yuan, J. S., Chen, F., & Stewart, C. N. (2013). Ecological Functions of Terpenoids in Changing Climates. Natural Products. 2913-2940. Springer Berlin Heidelberg.
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  • Syrenne, R. D., Shi, W., Stewart, C. N., & Yuan, J. S. (2012). Omics Platforms: Importance of Twenty-First Century Genome-Enabled Technologies in Seed Developmental Research for Improved Seed Quality and Crop Yield. Seed Development: OMICS Technologies toward Improvement of Seed Quality and Crop Yield. 43-57. Springer Netherlands.
  • Stewart, C. N., Peng, Y., Abercrombie, L. G., Halfhill, M. D., Rao, M. R., Ranjan, P., ... Yuan, J. S. (2010). Genomics of Glyphosate Resistance. Glyphosate Resistance in Crops and Weeds. 149-164. John Wiley & Sons, Inc..
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  • Hu, J., Tranel, P. J., Stewart, C. N., & Yuan, J. S. (2009). Molecular and Genomic Mechanisms of Non-Target-Site Herbicide Resistance. Weedy and Invasive Plant Genomics. 149-161. Wiley-blackwell.
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Conference Papers5
  • Liu, Z. H., Olson, M. L., Shinde, S., Wang, X., Hao, N., Yoo, C. G., ... Yuan, J. S. (2017). Synergistic maximization of the carbohydrate output and lignin processability by combinatorial pretreatment. International Congress on Energy 2017 - Topical Conference at the 2017 AIChE Annual Meeting. 2, 1002-1018.
  • Altangerel, N., Ariunbold, G. O., Gorman, C., Bohlmeyer, D., Yuan, J., Hemmer, P., Scully, M. O., & IEEE. (2016). Early, in vivo, Detection of Abiotic Plant Stress Responses via Raman Spectroscopy. 2016 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO).
  • Sams, C. E., Panthee, D. R., Charron, C. S., Kopsell, D. A., Barickman, T. C., & Yuan, J. S. (2014). Microarray analysis reveals selenium down-regulates glucosinolate biosynthesis in Arabidopsis shoots. Acta Horticulturae. 1040, 277-280.
  • Yao, D., Wei, Q., Xu, W., Syrenne, R. D., Yuan, J. S., & Su, Z. (2012). Comparative genomic analysis of NAC transcriptional factors to dissect the regulatory mechanisms for cell wall biosynthesis.. BMC Bioinformatics. 13 Suppl 15(S15), S10.
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  • Yuan, J. S., Burris, J., Stewart, N. R., Mentewab, A., & Stewart, C. N. (2007). Statistical tools for transgene copy number estimation based on real-time PCR.. BMC Bioinformatics. 8 Suppl 7(S7), S6.
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chaired theses and dissertations
First Name
Last Name
mailing address
Texas A&M University; Plant Pathology & Microbiology; 2132 TAMU
College Station, TX 77843-2132