My research laboratory focuses on the development of new microscopy techniques and, more specifically, single molecule microscopy approaches. Our theoretical and experimental investigations of the classical resolution problem showed that there is no resolution limit in a microscope, but that distances well below those estimated by Rayleighs criterion can be resolved. Using microscopy and other techniques, my research group and collaborators investigate the dynamics and transport of new therapeutics and their interactions with their target proteins in a cellular context; for example, engineered antibodies that target tumor cells. The main areas of application are cancer biology and immunology, autoimmunity, etc. We also have studied the molecular basis for the transport of therapeutic agents to specific subcellular compartment and related questions in pharmacokinetics.

education and training
selected publications
Academic Articles110
Conference Papers3
awards and honors
First Name
Last Name
mailing address
Texas A&M University; Biomedical Engineering; 3120 TAMU
College Station, TX 77843-3120