© The Editor(s) 2017. All rights are reserved. We present an overview of the positive youth development (PYD) perspective and the relational developmental systems (RDS) metatheory that frames this perspective. We describe the Lerner and Lerner model of PYD, and some of the findings from the 4-H Study of PYD regarding how thriving can be promoted among America's diverse youth. We also address limitations of this research, including the lack of a representative sample of minority youth participants in this study. We discuss how further RDS-based PYD research may be designed with the explicit goal of addressing some of the limitations of past work. We present implications for applying what we have learned from PYD research to programs that aim to promote thriving among minority youth in the U.S. and internationally.