Serum feline trypsin-like immunoreactivity following administration of ceruletide to healthy cats. | Academic Article individual record
abstract

OBJECTIVE: To determine changes in serum feline trypsin-like immunoreactivity (fTLI) in response to administration of ceruletide to healthy cats. ANIMALS: 11 healthy cats. PROCEDURES: Serum fTLI was determined, using a radioimmunoassay, before and 10, 20, 30, 40, and 50 minutes after IM administration of ceruletide (0.3 mg/kg [0.14 mg/lb]). RESULTS: Mean +/- SD baseline serum fTLI was 23.1 +/- 4.1 mg/L. There was a statistically significant, but clinically unimportant, increase in serum fTLI 10 and 30 minutes after ceruletide administration. CONCLUSIONS AND CLINICAL RELEVANCE: In healthy cats, administration of ceruletide induced a statistically significant, but clinically unimportant, increase in serum fTLI. Whether responses in cats with exocrine pancreatic disorders would be different is unknown, but results suggest that a ceruletide stimulation test would likely not be useful for differentiating between healthy cats and cats with subclinical chronic exocrine pancreatic disorders.

author list (cited authors)
Spillmann, T., Jacob, I., Steiner, J. M., Williams, D. A., & Failing, K.
publication date
2000
keywords
  • Ceruletide
  • Caerulein
  • Pancreatic Diseases
  • Trypsin
  • Radioimmunoassay
  • Cats
  • Cat Diseases
  • Animals
citation count

1