Calcium Entry Channels in Non-Excitable Cells | Chapter individual record
abstract

2017 by Taylor & Francis Group, LLC. The calcium ion serves as a versatile and universal second messenger to control a myriad of biological processes, including muscle contraction, neurotransmission, hormone secretion, immune cell activation, cell motility, and apoptosis [1-3]. The calcium release-activated calcium (CRAC) channel mediated by ORAI and stromal interaction molecule (STIM) constitutes one of the primary Ca2++ entry routes in non-excitable cells [4-6] (see Chapter 2). The CRAC channel is regarded as a prototypical example of store-operated Ca2++ entry (SOCE), in which the depletion of Ca2++ store in the endoplasmic reticulum (ER) induces calcium inux from the extracellular space. Over the past decade, tremendous progress has been made with respect to.

book title

Calcium Entry Channels in Non-Excitable Cells

authors
author list (cited authors)
He, L., Zhang, Q., Zhou, Y., & Huang, Y.
editor list (cited editors)
Kozak, J. A., & Putney, J. W.
publication date
2017
publisher
CRC Press Publisher
identifier
372047SE
Digital Object Identifier (DOI)
International Standard Book Number (ISBN) 13
9781498752725
start page
145
end page
160